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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7775 | A2764 dihydrochloride | Potassium Channel | |
A2764 dihydrochloride is a highly selective inhibitor of TRESK. | |||
T8682 | Vazegepant hydrochloride | Vazegepant HCl | CGRP Receptor |
Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study. | |||
T1092 | Zolmitriptan | 311C90,BW-311C90 | 5-HT Receptor |
Zolmitriptan (311C90) selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries and 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and... | |||
T0203 | Sumatriptan succinate | GR 43175 | 5-HT Receptor |
Sumatriptan succinate (GR 43175), a serotonin1 (5-HT1) receptor agonist, is used in the acute treatment of a migraine headache. | |||
T1602 | Valproic acid sodium salt | Sodium Valproate | Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , HDAC , Autophagy |
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into its active form, valproate ion, in blood. Although the mecha... | |||
T11326 | Frovatriptan succinate hydrate | Frovelan,Frova | 5-HT Receptor |
Frovatriptan succinate hydrate (Frova) is effective in treating the full spectrum of migraine including the associated symptoms of nausea, vomiting, photophobia, and phonophobia. Frovatriptan succinate hydrate can also b... | |||
T6474 | Divalproex Sodium | Valproate semisodium,Epival | HDAC |
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme... | |||
T7064 | Valproic Acid | Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid | Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy |
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research. | |||
T17194 | Ubrogepant | MK-1602 | CGRP Receptor |
Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies. | |||
T8993L | BGC-20-1531 hydrochloride(1186532-61-5 free base) | BGC-20-1531 hydrochloride,GTPL3380 hydrochloride,AP-1531 hydrochloride | Prostaglandin Receptor |
BGC-20-1531 hydrochloride(1186532-61-5 free base) (GTPL3380 hydrochloride) is a EP4 antagonist for the treatment of acute migraine. | |||
T68067L | Etilefrine pivalate HCl | Etilefrine pivalate HCl(100696-30-8 Free base) | |
Etilefrine pivalate HCl is an orally active compound for the treatment of migraine headaches. | |||
T5479 | AMG 333 | AMG-333 | TRP/TRPV Channel |
AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the Treatment of Migraine. | |||
T6571 | Lomerizine dihydrochloride | Terranas,Lomerizine 2HCl,Lomerizine hydrochloride,KB-2796 | Calcium Channel |
Lomerizine dihydrochloride (KB-2796) is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine. | |||
T68145 | Stacofylline | ||
Stacofylline is a xanthine derivative that is used to treat migraine headaches. | |||
T27932 | LY-2300559 | LY2300559 | GluR |
LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine. | |||
T31208 | Dasolampanel | NGX-426,NGX 426,NGX426 | GluR , iGluR |
Dasolampanel (NGX-426) is an orally available ionotropic glutamate receptor AMPA and Kainate receptor antagonist for the study of chronic pain disorders, including neuropathic pain and migraine. | |||
T25615 | Lanepitant | LY303870,LY-303870,LY 303870 | Others |
Lanepitant (LY303870) is a nonpeptide neurokinin-1 (NK-1) antagonist with analgesic activity that inhibits neurogenic dura mater inflammation and is used for the prevention of migraine. | |||
T69096 | Femoxetine hydrochloride | 5-HT Receptor | |
Femoxetine hydrochloride is a selective 5-hydroxytryptamine reuptake inhibitor used in the study of migraine, depression and eating disorders. | |||
T8666 | Naratriptan | 5-HT Receptor | |
Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches. | |||
T76874 | Erenumab | AMG-334 | CGRP Receptor |
Erenumab is a whole-human monoclonal antibody. Erenumab inhibits calcitonin gene-related peptide (CGRP) receptors. Erenumab can be used to prevent migraine attacks. |