methanesulfonate — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3111	Abemaciclib methanesulfonate	abemaciclib mesylate,LY2835219,LY2835219 mesylate,LY2835219 (methanesulfonate)	CDK
	Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM).		CDK
T21518	Colistin methanesulfonate sodium salt	Colistin Methanesulfonate (sodium salt)	Cell wall , Antibacterial
	Colistin methanesulfonate sodium salt (Colistimethate Sodium) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.		Cell wall , Antibacterial
T9985	Methyl methanesulfonate		DNA Alkylation
	Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders.		DNA Alkylation
T12425	PF-06424439 methanesulfonate		Acyltransferase , Transferase
	PF-06424439 methanesulfonate, an orally administered, potent, and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM, demonstrates slow reversibility and time-dependent inh...		Acyltransferase , Transferase
T21483	Tricaine methanesulfonate	MS-222	Others
	Tricaine methanesulfonate (MS-222) (TMS) is an anesthetic. Many hatcheries and research studies use TMS to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures.		Others
T9894	2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate		Others
	2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate is a natural product that can be used as reference standards.		Others
T38979	CYH33 methanesulfonate	CYH33 methanesulfonate
	CYH33 methanesulfonate is a highly selective and orally active inhibitor of PI3Kα, with IC50 values of 5.9 nM, 598 nM, 78.7 nM, and 225 nM against the α, β, δ, and γ isoforms, respectively. This compound effectively inhi...
T13087	Tariquidar methanesulfonate, hydrate	XR9576 methanesulfonate, hydrate	Others
	Tariquidar methanesulfonate, hydrate is a potent and specific P-glycoprotein (P-gp) inhibitor(Kd of 5.1 nM).		Others
T1072	Loxeen	Pridinol methanesulfonate	AChR
	Loxeen (Pridinol methanesulfonate) is used as an anticholinergic and as an antiparkinsonian agent.		AChR
T1275	Phentolamine mesylate	Phentolamine methanesulfonate,Phentolamine mesilate	Adrenergic Receptor
	Phentolamine mesylate (Phentolamine methanesulfonate) is a nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEAS...		Adrenergic Receptor
T68534	FK-448 methanesulfonate
	FK-448 methanesulfonate is a chymotrypsin inhibitor that has been shown to affect intestinal absorption of insulin in rats and dogs .
T69185	INO-1001 methanesulfonate
	INO-1001 methanesulfonate is an isoindolinone derivative and potent inhibitor of the nuclear enzyme poly (ADP-ribose) polymerase (PARP) with chemosensitization and radiosensitization properties.
T25722	Lifarizine methanesulfonate
	Lifarizine methanesulfonate is a modulator of sodium-calcium channel that reduces ischemic brain damage.
T5133	Dabigatran Etexilate Mesylate	BIBR 1048MS,Dabigatran etexilate methanesulfonate	Thrombin
	Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI, Ki: 4.5 nM).		Thrombin
T23148	Phenamil methanesulfonate	Phenamil	Others
	TRPP3 channel inhibitor		Others
T34224	Quinacrine methanesulfonate	Mepacrine dimethanesulfonate salt
	Quinacrine methanesulfonate is a bioactive chemical.
T12417	PF-04217903 methanesulfonate		c-Met/HGFR
	PF-04217903 methanesulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for human c-Met).		c-Met/HGFR
T71096	GCC-4401C methanesulfonate
	GCC-4401C methanesulfonate is a factor Xa inhibitor similar to rivaroxaban that is currently under development for venous thromboembolic disease (VTE).
T13567	BCX 1470 methanesulfonate		Serine Protease
	BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.		Serine Protease
T2226	Pergolide mesylate	Pergolide mesylate salt,LY127809,Pergolide methanesulfonate	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
	Pergolide mesylate salt(LY127809) is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES.		Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor