Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,080.00 | |
50 mg | 6-8 weeks | $ 1,410.00 | |
100 mg | 6-8 weeks | $ 2,140.00 |
Description | BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively. |
Targets&IC50 | Trypsin:326 nM , FD:96 nM , C1s:1.6 nM |
In vitro | BCX 1470 methanesulfonate is an inhibitor serine protease. BCX 1470 blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro. |
In vivo | BCX 1470 methanesulfonate blocked the development of RPA-induced edema in the rat. |
Molecular Weight | 398.48 |
Formula | C15H14N2O5S3 |
CAS No. | 217099-44-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 33.33 mg/mL (83.64 mM)
You can also refer to dose conversion for different animals. More
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BCX 1470 methanesulfonate 217099-44-0 Proteases/Proteasome Serine Protease inhibitor inhibit