line — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T21588	Olomoucine		ERK , CDK
	Olomoucine is an ATP competitive inhibitor of Cdk2/cyclin A, Cdc2/CyclinB, CDK2/CyclinE, CDK5/p35, and ERK1/p44 MAP kinase with IC50s of 7, 7, 7, 3 and 25 µM, respectively. Olomoucine regulates cell cycle and exhibits an...		ERK , CDK
T6798	Tretazicar	5-Aziridino-2,4-dinitrobenzamide,CB1954,NSC 115829	DNA Alkylator/Crosslinker , DNA Alkylation
	CB1954(Tretazicar (NSC-115829)), an anticancer prodrug, is activated by NAD(P)H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cy...		DNA Alkylator/Crosslinker , DNA Alkylation
T4297	Flibanserin	BIMT-17BS,Girosa,BIMT-17	Dopamine Receptor , 5-HT Receptor
	Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor serum aminotransferase elevations during treatment but has n...		Dopamine Receptor , 5-HT Receptor
T9340	1-phenyl-3,4-dihydroisochinoline	3,4-Dihydro-1-phenylisoquinoline	Others
	1-phenyl-3,4-dihydroisochinoline is a structural analog of the neurotransmitter dopamine that interacts with dopamine receptors in the central nervous system. It has been studied as a potential therapeutic agent for the ...		Others
T4713	Phosphorylcholine chloride calcium salt tetrahydrate	Phosphocholine chloride calcium salt tet,CalciuM Phosphorylcholine Tetrahydrate	Others , Endogenous Metabolite
	Phosphorylcholine chloride calcium salt tetrahydrate (Phosphocholine chloride calcium salt tet) is a small haptenic molecule, is found in a wide variety of organisms. Human hepatic tumors undergo an elevation in the conc...		Others , Endogenous Metabolite
T2O2683	L-Proline	L-(-)-Proline,proline	Endogenous Metabolite
	L-Proline (proline) is a nonessential amino acid in humans. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles.		Endogenous Metabolite
T11054	DL-Norvaline	2-Aminopentanoic acid	Arginase , Endogenous Metabolite
	DL-Norvaline (2-Aminopentanoic acid) is a non-competitive inhibitor of arginase.		Arginase , Endogenous Metabolite
T0268	Lobeline hydrochloride	α-Lobeline hydrochloride,L-Lobeline hydrochloride	AChR
	Lobeline hydrochloride (α-Lobeline hydrochloride) is a nicotinic receptor agonist, acting as an effective antagonist at both α4β2 and α3β2 neuronal nicotinic receptor subtypes.		AChR
T8634	8-Bromotheophylline	Bromotheophylline	Others
	8-Bromotheophylline (Bromotheophylline) is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline. From this mixture, 8-Bromotheophylline acts as a weak diuretic that has been used al...		Others
T6703	Tetrahydrozoline hydrochloride	Murine Plus,Tetryzoline hydrochloride,Tyzine,Tetrahydrozoline HCl	Adrenergic Receptor
	Tetrahydrozoline hydrochloride (Murine Plus) is an imidazoline derivative with alpha receptor agonist activity.		Adrenergic Receptor
T0248	Clorprenaline hydrochloride	Clorprenaline HCl,NSC 334693	Adrenergic Receptor
	Clorprenaline hydrochloride (Clorprenaline HCl) is a beta-2 adrenergic agonist with bronchodilator activity.		Adrenergic Receptor
T1208	Citicoline sodium	Citicoline sodium salt,CDP-choline	Apoptosis , Others , Endogenous Metabolite
	Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demons...		Apoptosis , Others , Endogenous Metabolite
T6805	Choline bitartrate	2,3,4-trihydroxy-4-oxobutanoate,2-hydroxyethyl(trimethyl)azanium	Others , AChR
	Choline bitartrate (2-hydroxyethyl(trimethyl)azanium) is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acetylcho...		Others , AChR
T27636	Ispronicline	AZD-3480,RJR-1734,AZD 3480,TC 1734,AZD3480,TC-01734,TC-1734-112	AChR
	Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitive effects.Ispronicline has a high affinity for the α4β2 nAChR with ...		AChR
T3978	Linerixibat	GSK2330672,Iinerixibat	HBV
	Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties.		HBV
TN2549	1-Methoxycarbonyl-β-carboline	1-Methoxycarbonyl-beta-carboline	Others
	1-Methoxycarbonyl-β-carboline (1-Methoxycarbonyl-beta-carboline) is an alkaloid from Ailanthus altissima.		Others
T25441	Fructosylvaline	Fru-val,N-Fructosyl Valine	Others
	Fructosylvaline（Fru-val） is present in miso, white wine and sake and has been associated with oxidative browning of white wine and sake.		Others
T68135L	(Rac)-Sabcomeline HCl	sabcomeline HCl(149156-36-5 Free base)	AChR
	Sabcomeline HCl is an M1 receptor agonist that can be used to study Alzheimer's disease.		AChR
T2285	Encenicline hydrochloride	EVP-6124 (hydrochloride),EVP-6124 hydrochloride	AChR
	Encenicline hydrochloride (EVP-6124 hydrochloride) is a new-type partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).		AChR
T1039	Choline chloride	Biocolina,Biocoline,Hepacholine	AChR
	Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in li...		AChR