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Choline chloride

Catalog No. T1039 CAS 67-48-1

Synonyms: Biocolina, Biocoline, Hepacholine

Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

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Choline chloride, CAS 67-48-1

Pack Size	Availability	Price/USD
50 mg	In stock	$ 33.00
100 mg	In stock	$ 47.00
200 mg	In stock	$ 60.00
500 mg	In stock	$ 95.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 99.89%

Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
In vitro	After oral administration of Choline chloride, clinical symptoms include restlessness, accelerated respiration, reduced activity, convulsions, wrinkled fur, unsteady gait, and respiratory distress. Choline chloride exhibits low acute oral toxicity. Some animals exhibit diarrhea following ingestion of Choline chloride. In one study, the autopsy revealed pulmonary inflammation in 30% of the rats in the high-dose group.
In vivo	In cell culture, a deficiency of choline can lead to apoptosis, also known as programmed cell death.

Synonyms	Biocolina, Biocoline, Hepacholine
Molecular Weight	139.63
Formula	C5H14ClNO
CAS No.	67-48-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 27 mg/mL (193.4 mM)

H2O: 26 mg/mL (186.2 mM)

DMSO: 27 mg/mL (193.4 mM)

References and Literature

1. Lu XZ, et al. Br J Pharmacol. 2015 May 8

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Traditional Chinese Medicine Monomer Library Miao medicine Compound Library Anti-Neurodegenerative Disease Compound Library Membrane Protein-targeted Compound Library Natural Product Library Natural Product Library for HTS Anti-COVID-19 Traditional Chinese Medicine Compound Library Food as Medicine Compound Library Clinical Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Choline chloride 67-48-1 Neuroscience AChR anti-inflammatory alpha7 nicotinic receptor Nicotinic acetylcholine receptors Choline Biocolina inhibit Biocoline Inhibitor Choline Chloride Hepacholine Endogenous Metabolite analgesic nAChR inhibitor

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