lateral — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T39924	NF-κΒ activator 2		NF-κB
	NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM. By enhancing NF-κB expression and activation, it induces SOD 2 synthesis, rendering it useful for amyo...		NF-κB
T22911	β-N-methylamino-L-alanine hydrochloride	L-BMAA hydrochloride	Others
	β-N-methylamino-L-alanine hydrochloride (L-BMAA hydrochloride) is a neurotoxin produced by cyanobacteria. L-BMAA hydrochloride could cause amyotrophic lateral sclerosis (ALS) and possibly other neurodegenerative diseases...		Others
T13553	Arimoclomol	BRX-220 free base	HSP
	Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).		HSP
T60120	SOD1-Derlin-1 inhibitor 56-59		Others
	SOD1-Derlin-1 inhibitor 56-59 is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor 56-59 is potential in Amyotrophic lateral sclerosis (ALS) research.		Others
T0349	Riluzole	PK 26124,RP-54274	GABA Receptor , Sodium Channel , NMDAR
	Riluzole (RP-54274) is a glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.		GABA Receptor , Sodium Channel , NMDAR
T21995	XAP044		GluR
	XAP044 is a mGlu7-selective antagonist which inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice with a half-maximal blockade at 88 nm[1].		GluR
TMS2179	Zeatin		Others
	Zeatin is a cytokinin derived from adenine. Zeatin was discovered in immature corn kernels from the genus Zea. It promotes growth of lateral buds and when sprayed on meristems stimulates cell division to produce bushier ...		Others
T60108	PDGFR Tyrosine Kinase Inhibitor III	PDGF Receptor Tyrosine Kinase Inhibitor III	PDGFR
	PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor that inhibits PDGFR, EGFR, FGFR, PKA, and PKC, respectively. PDGF...		PDGFR
T60119	SOD1-Derlin-1 inhibitor-1	SOD1-Derlin-1 Inhibitor 56-20	Others
	SOD1-Derlin-1 inhibitor-1 (SOD1-Derlin-1 Inhibitor 56-20) (compound 56-20) is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor-1 inhibits SOD1 G93A -Derlin-1 complex with an IC 50 value of 7.11 μM. SOD1...		Others
T77484	Atibuclimab		TNF
	Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region. Atibuclimab can be used to treat amyotrophic lateral sclerosis. Atibuclimab reduces LPS-indu...		TNF
T2532	Tauroursodeoxycholate	Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA	Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
	Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. Tauroursodeoxycholate is the more hydrophilic form of ursode...		Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
T14390L	(2R,3S)-Azelaprag		Apelin receptor
	(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist with an EC50 for Apelin receptors of 0.012 µM.(2R,3S)-N-(4-(...		Apelin receptor
T37298	Spinacine		Endogenous Metabolite
	Spinacine has been isolated from spinach and the roots of Panax ginseng. This conformationally constrained amino acid is a structural element in certain biologically active compounds as glucagon antagonists and angiotens...		Endogenous Metabolite
T35689	MTP 131 acetate		Others
	MTP 131 is a mitochondria-targeted peptide antioxidant.1,2It localizes to the mitochondria and reducestert-butyl hydroperoxide-induced lipid peroxidation and apoptosis in SH-SY5Y cells when used at concentrations ranging...		Others
T31978	GM-608	GM-606,GM-607,GM-604,GM-603,GM-605,GM-602
	GM-604(alirinetide) is a potential treatment for amyotrophic lateral sclerosis and ischemic stroke.
T25852	Naxillin
	Naxillin is the first non-auxin-like molecule that promotes root branching which acts as a specific lateral root development modulator.
T24814	Sortin2	Sortin-2,Sortin 2
	Sortin2 is a sorting inhibitor that acts upstream from the morphological marker of lateral root primordium formation, the mitotic activity.
T35135	WN1316	WN 1316,WN-1316
	WN1316 is a unique neuroprotectant against oxidative injury, being a highly promising remedy for the treatment of amyotrophic lateral sclerosis (ALS).
T70892	K812
	K812 is an ASK1-specific inhibitor discovered to prolong survival in a mouse model of amyotrophic lateral sclerosis.
T11214	EPI-589		Others
	EPI-589, a quinone derivative and oxidoreductase enzyme inhibitor, is considered safe and well tolerated, showing promise for the treatment of amyotrophic lateral sclerosis (ALS).		Others