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Search Results for " first-generation "

20

Compounds

Cat No. Product Name Synonyms Targets
T8134 Cefathiamidine Antibacterial , Antibiotic
Cefathiamidine exhibits a wide spectrum of antimicrobial activity against bacteria. Cefathiamidine is used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis
T8345 Carbutamide Others
Carbutamide is a sulfonylurea antidiabetic agent with hypoglycemic activity.
T6451 Clodronic acid disodium salt Loron,Clodronate Disodium,Lodronate Others
Clodronic acid disodium salt (Lodronate), a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.
T0370 Pheniramine maleate Daneral,Inhiston,Trimetose 5-HT Receptor , Histamine Receptor
Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re...
T0141 Cephalonium Cefalonium Others
Cephalonium (Cefalonium) is a first-generation cephalosporin antibiotic.
T8063 Cephapirin Benzathine Others , Antibacterial , Antibiotic
Cephapirin Benzathine is a semisynthetic, broad-spectrum, first-generation cephalosporin with antibacterial activity.
T0141L Cefalonium Dihydrate(5575-21-3 free base) Cefalonium Dihydrate Others
Cefalonium Dihydrate(5575-21-3 free base) is a first-generation cephalosporin antibiotic.
T0371 Gliquidone AR-DF 26,Glurenorm Potassium Channel
Gliquidone (AR-DF 26) is a potent, second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds, gliquidone exerts greater binding affinity to SUR1 and increased potency compared...
T8062 Cefazedone Refosporen Others , Antibacterial , Antibiotic
Cefazedone (Refosporen) is a semisynthetic first-generation cephalosporin with activity against Gram-positive and Gram-negative bacteria[1].
T9225 Vebicorvir ABI-H0731 HBV
Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor, has demonstrated effective antiviral activity.
T8457 NPS2390 GluR
NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)
T0092 Antazoline hydrochloride Phenazocine HCl,Phenazoline hydrochloride,Antazoline HCl Histamine Receptor
Antazoline hydrochloride (Phenazoline hydrochloride), a first-generation antihistamine, can bind to the histamine H1 receptor and block the action of endogenous histamine.
T21419 Diphenhydramine Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255 Histamine Receptor
Diphenhydramine (Syntedril), a first-generation antihistamine possessing antiemetic, antitussive, anticholinergic, and sedative properties, is mainly used in the treatment of allergies. Diphenhydramine is also used in th...
T0445L Promethazine hydrochloride Promethazine HCl,Phenergan Adrenergic Receptor , Histamine Receptor
Promethazine hydrochloride (Promethazine HCl) , the first-generation antihistamine, is a strong antagonist of the H1 receptor and a moderate antagonist of the mACh receptor, moderate affinity for 5-HT2A, 5-HT2C, D2 and α...
T0199 Cephradine Anspor,Cephradin,Velosef,SQ-11436,Sefril TOPK , Antibacterial , Antibiotic
Cephradine (Anspor) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.
T7941 Imipramine hydrochloride Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine Serotonin Transporter
Imipramine hydrochloride (Imipramine HCl) is a first generation tricyclic antidepressant that acts primarily as an inhibitor of serotonin and norepinephrine transporters (Kds = 1.4 and 37 nM, respectively).Imipramine hyd...
T16472 Pericyazine Propericiazine,RP 8909 Dopamine Receptor
Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist. Pericyazine is a first-generation antipsychotic drug that is used as an adjunct to the short-term management of severe anxiety states and psych...
T0059 Diphenylpyraline hydrochloride 4-Diphenylmethoxy-1-methylpiperidine hydrochloride Histamine Receptor
Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) is used in the treatment of Parkinsonism.It is a first-generation antihistamine with anticholinergic effects, functions as a dopamine re...
T21390 Fexofenadine Carboxyterfenadine,Telfast,MDL 16.455,Allegra Histamine Receptor
Fexofenadine (Carboxyterfenadine), an antihistamine pharmaceutical drug, is used to treat allergy symptoms, such as nasal congestion, hay fever, and urticaria. Compared to first-generation antihistamines, Fexofenadine is...
T0816 Acetohexamide Acetohexamid,Dymelor,Gamadiabet Potassium Channel , NADPH
Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (KIR6.2) wi...

Compounds

Cefathiamidine
T8134
Synonym:
Target: Antibacterial, Antibiotic
Carbutamide
T8345
Synonym:
Target: Others
Clodronic acid disodium salt
T6451
Synonym: Loron,Clodronate Disodium,Lodronate
Target: Others
Pheniramine maleate
T0370
Synonym: Daneral,Inhiston,Trimetose
Target: 5-HT Receptor, Histamine Receptor
Cephalonium
T0141
Synonym: Cefalonium
Target: Others
Cephapirin Benzathine
T8063
Synonym:
Target: Others, Antibacterial, Antibiotic
Cefalonium Dihydrate(5575-21-3 free base)
T0141L
Synonym: Cefalonium Dihydrate
Target: Others
Gliquidone
T0371
Synonym: AR-DF 26,Glurenorm
Target: Potassium Channel
Cefazedone
T8062
Synonym: Refosporen
Target: Others, Antibacterial, Antibiotic
Vebicorvir
T9225
Synonym: ABI-H0731
Target: HBV
NPS2390
T8457
Synonym:
Target: GluR
Antazoline hydrochloride
T0092
Synonym: Phenazocine HCl,Phenazoline hydrochloride,Antazoline HCl
Target: Histamine Receptor
Diphenhydramine
T21419
Synonym: Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255
Target: Histamine Receptor
Promethazine hydrochloride
T0445L
Synonym: Promethazine HCl,Phenergan
Target: Adrenergic Receptor, Histamine Receptor
Cephradine
T0199
Synonym: Anspor,Cephradin,Velosef,SQ-11436,Sefril
Target: TOPK, Antibacterial, Antibiotic
Imipramine hydrochloride
T7941
Synonym: Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine
Target: Serotonin Transporter
Pericyazine
T16472
Synonym: Propericiazine,RP 8909
Target: Dopamine Receptor
Diphenylpyraline hydrochloride
T0059
Synonym: 4-Diphenylmethoxy-1-methylpiperidine hydrochloride
Target: Histamine Receptor
Fexofenadine
T21390
Synonym: Carboxyterfenadine,Telfast,MDL 16.455,Allegra
Target: Histamine Receptor
Acetohexamide
T0816
Synonym: Acetohexamid,Dymelor,Gamadiabet
Target: Potassium Channel, NADPH
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TargetMol