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Cat No. | Product Name | Synonyms | Targets |
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T12697 | Refametinib R enantiomer | RDEA119 R enantiomer,Refametinib R enantiomer,BAY 869766 R enantiomer | MEK |
Refametinib R enantiomer (RDEA119 R enantiomer) is an MEK inhibitor with an EC50 of 2.0-15 nM.Refametinib (R enantiomer) has anticancer activity and can be used in cancer research. | |||
T12064 | Niraparib (R-enantiomer) | MK 4827 (R-enantiomer),Niraparib R-enantiomer | PARP |
Niraparib R-enantiomer (MK 4827 R-enantiomer) is an inhibitor of PARP1(IC50 of 2.4 nM). | |||
T13140 | Umbralisib R-enantiomer | TGR-1202 R-enantiomer,RP5264 R-enantiomer | PI3K |
Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202. The IC50 of Umbralisib R-enantiomers against δPI3 kinase is at least 20 times lower than that of the in... | |||
T15263 | Selisistat R-enantiomer | EX-527 (R-enantiomer) | Sirtuin |
Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM). | |||
T7058 | Selisistat S-enantiomer | EX-527 S-enantiomer,EX-527 (S-enantiomer) | Sirtuin |
Selisistat S-enantiomer (EX-527 S-enantiomer) is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3. | |||
T17102 | Tipifarnib (S enantiomer) | Tipifarnib S enantiomer,(S)-(-)-R-115777,(S)-Tipifarnib,IND-58359 S enantiomer | Transferase |
Tipifarnib S enantiomer ((S)-(-)-R-115777) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50: 0.6 nM). | |||
T11129L | Duvelisib (R enantiomer) hydrochloride | IPI-145 R enantiomer HCl,Duvelisib (R enantiomer) hydrochloride(1261590-48-0 Free base),INK1197 R enantiomer HCl | PI3K |
Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) is a PI3K inhibitor. Duvelisib (R enantiomer) hydrochloride is the less active enantiomer of Duvelisib. | |||
T6156 | Ruxolitinib (S enantiomer) | S-Ruxolitinib,Ruxolitinib S enantiomer,INCB018424,INCB18424 | Tyrosine Kinases , JAK |
Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor. | |||
T12831 | SAR405 R enantiomer | Others | |
SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is an inhibitor of PIK3C3/Vps34. | |||
T19618 | (R)-(-)-JQ1 Enantiomer | Epigenetic Reader Domain | |
(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay) | |||
T9825 | CORT-108297 Enantiomer | Others | |
CORT-108297 Enantiomer is an enantiomer of CORT-108297 which is an antagonist of the Glucocorticoid Receptor. | |||
T10819 | Cipropride S enantiomer | Others | |
Cipropride S enantiomer is the S enantiomer of cipropride which is an antiemetic drug. | |||
T19112L | Sacubitril Enantiomer | 2R,4S-Sacubitril,ahu377 isomer 2 | Others |
Sacubitril Enantiomer (ahu377 isomer 2) is the enantiomer of Sacubitril which is a neprilysin inhibitor. | |||
T7695 | PNU-282987 S enantiomer free base | AChR | |
PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR). | |||
T67881 | Acalabrutinib enantiomer | R-Acalabrutinib | BTK |
Acalabrutinib enantiomer (R-Acalabrutinib) is a chemical compound that belongs to the class of Bruton’s tyrosine kinase (BTK) inhibitors. Acarabitinib enantiomers can be used in the study of cancer, autoimmune diseases a... | |||
T22450 | Tyrphostin B44, (+) enantiomer | EGFR | |
Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer. | |||
T80678 | (S)-AK-242 | (-)-Resatorvid,(S)-Resatorvid,AK-242 (S enantiomer),(-)-AK-242 | Others |
(S)-AK-242 ((S)-Resatorvid) is a cytokine inhibitor used in the treatment of heart disease, autoimmune disease, and inflammatory disease. | |||
T10552 | Bitopertin (R enantiomer) | RO4917838 (R enantiomer),RG1678 (R enantiomer),Bitopertin R enantiomer | GlyT |
Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a noncompetitive glycine reuptake inhibitor and inhibits glycine uptake at human GlyT1 (IC50: 25 nM). | |||
T11391 | Gepotidacin S enantiomer | GSK2140944 S enantiomer | Others |
Gepotidacin S enantiomer is an S enantionmer of gepotidacin. | |||
T11173 | Elacestrant S enantiomer | RAD1901 S enantiomer | Others |
Elacestrant S enantiomer is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively. |