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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0131 | Cepharanthine | NSC-623442 | Apoptosis , TNF , HIV Protease , Autophagy |
Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and inhibits cytokine production. | |||
T26396 | 6-Hydroxy-DOPA | 6-Hydroxy-DL-DOPA | DNA/RNA Synthesis |
6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1. | |||
T9318 | TP0586532 | Others | |
TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk. | |||
T8055 | TFEB activator 1 | (1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,,Curcumin analog compound C1,Curcumin analog C1,RPN77612 | Others , Autophagy |
TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer's disease. | |||
T16740 | RH1 | NSC 697726 | Others |
RH1 is an effective bioreductive agent. | |||
T16802 | Lonapalene | RS4317 | Others |
Lonapalene is a topically effective inhibitor of 5-lipoxygenase. | |||
T16427 | Padsevonil | UCB-0942 | Others |
Padsevonil is an effective antiepileptic compound. | |||
T10718L | CCT241533 hydrochloride | Chk | |
CCT241533 hydrochloride is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM). | |||
T39764 | ALK2-IN-4 | ALK2-IN-4 | |
ALK2-IN-4, a highly effective ALK2 inhibitor. | |||
T26360 | Benperidol | R4584,R-4584,Anquil,McN-JR-4584,R 4584 | |
Benperidol (Anquil) is a butanone analog with antipsychotic and stabilizing properties, and has been shown to be effective in blocking D2 receptors.Benperidol can be used in positron emission tomography (PET) scanning to... | |||
T3453 | WAY-100635 maleate | 5-HT Receptor | |
WAY-100635 is a specific and effective 5-HT receptor antagonist (IC50=0.95 nM). | |||
T15643 | Kainic acid | Others | |
In the CNS, Kainic acid is an effective agonist at excitatory amino acid receptor subtypes. | |||
T16557 | PNU-159682 | Topoisomerase | |
PNU-159682 is a highly effective metabolite of the anthracycline nemorubicin. PNU-159682 has outstanding cytotoxicity. PNU-159682 is an effective ADCs cytotoxin. | |||
T15811 | LY2955303 | Others , Retinoid Receptor | |
LY2955303 is an effective and selective antagonist of retinoic acid receptor gamma (RARγ, Ki = 1.09 nM). | |||
T15649 | KDM5-IN-1 | Histone Demethylase | |
KDM5-IN-1 is an effective and selective inhibitor of KDM5 with an IC50 of 15.1 nM. | |||
T15628 | JT010 | TRP/TRPV Channel | |
JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM). | |||
T14522 | Beaucage reagent | DNA/RNA Synthesis | |
Beaucage reagent, which is found to be effective in causing DNA cleavage. | |||
T34793 | TC-T 6000 | TCT6000,TC-T6000,TCT 6000 | |
TC-T 6000 is an effective inhibitor of balanced nucleoside transporter protein 4 (ENT4) (IC50 = 74.4 nM). | |||
T3434 | BAY1217389 | Kinesin | |
BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM). | |||
T15820 | Mibampator | LY451395 | iGluR |
Mibampator (LY451395) is an effective and selective AMPA receptor potentiator. |