Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RH1 is an effective bioreductive agent.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 197.00 | |
5 mg | In stock | $ 446.00 | |
10 mg | In stock | $ 718.00 | |
25 mg | In stock | $ 1,450.00 | |
50 mg | In stock | $ 1,980.00 |
Description | RH1 is an effective bioreductive agent. |
In vitro | RH1 causes apoptosis in a time- and concentration-dependent manner in NQ16 cells. Treatment of NQ16 cells with RH1 (50 and 100 nM) for 60 and 120 min causes a significant increase (p< 0.05) in cross-linked DNA [1]. |
In vivo | RH1 displays antitumor activity in a dose-dependent manner against NQ16 tumors growing in athymic mice. Low-dose RH1 (0.1 mg/kg) also causes a significant reduction in tumor volume between treated mice and controls. RH1 treatment (0.4 mg/kg and 0.2 mg/kg) of mice bearing NQ16 tumors induces an obvious reduction in tumor volume between treated groups and controls as early as 5 days after the treatment period ended [2]. |
Synonyms | NSC 697726 |
Molecular Weight | 234.25 |
Formula | C12H14N2O3 |
CAS No. | 221635-42-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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RH1 221635-42-3 Others NSC697726 NSC 697726 RH-1 RH 1 NSC-697726 inhibitor inhibit