developmental — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7440	P,p'-DDE	p,p'-dichlorodiphenyldichloroethylene,4,4'-DDE,Dichlorodiphenyldichloroethylene	Androgen Receptor , Drug Metabolite
	p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT		Androgen Receptor , Drug Metabolite
TN3910	Ecdysone		Apoptosis , ATPase , Glucocorticoid Receptor , Potassium Channel , Sodium Channel , Endogenous Metabolite , Autophagy
	Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signaling through Ecdysone receptor isoform B1 is required cell a...
T19739	Simazine	Tafazine,Aquazine,Radocon,Herbex	Others
	Simazine (Tafazine) is a chlorotriazine herbicide and pesticide. Simazine may lead to testicular degeneration, neuroendocrine disruption, mammary cancer, and fetal developmental delays.		Others
T12360	Para-Nitroblebbistatin	p-Nitroblebbistatin	Myosin
	para-Nitroblebbistatin (p-Nitroblebbistatin) is a non-cytotoxic, fluorescent, photostable and specific Myosin II inhibitor. para-Nitroblebbistatin can be used in the study of the special role of myosin II in developmenta...		Myosin
T7913	2-Bromobiphenyl		Others
	2-Bromobiphenyl is a persistent organic pollutant (POP) found primarily in soil and water. It is a known human carcinogen and has been linked to a variety of health effects including reproductive and developmental toxici...		Others
T39252L	5-[(1S,2S)-2-[(Cyclopropylmethyl)amino]cyclopropyl]-N-(tetrahydro-2H-pyran-4-yl)thiophene-3-carboxamide hydrochloride		Others
	5-[(1S,2S)-2-[(Cyclopropylmethyl)amino]cyclopropyl]-N-(tetrahydro-2H-pyran-4-yl)thiophene-3-carboxamide hydrochloride is a cyclopropanoid enzyme compound that acts as a lysine-specific demethylase-1 inhibitor for schizop...		Others
T6368	Abscisic Acid	Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin）	Others , Proton pump , Endogenous Metabolite
	Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth.		Others , Proton pump , Endogenous Metabolite
T5061	Lumichrome	7,8-Dimethylalloxazine	Others
	Lumichrome (7,8-Dimethylalloxazine) is a natural metabolite of riboflavin. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at nanomolar concentrations. Lumichrom...		Others
T5623	Bisphenol A		Others , Endogenous Metabolite
	Bisphenol A is an endogenous metabolic compound of phenols and is widely used in the production of epoxy resins and polycarbonate plastics. It is reproductive, developmental and systemic toxicant and is often classified ...		Others , Endogenous Metabolite
T3746	Dimethyl phthalate	Solvanom,Avolin,Fermine	Others
	Dimethyl phthalate (Fermine) has many uses, including in solid rocket propellants, plastics, and insect repellants. Acute (short-term) exposure to dimethyl phthalate, via inhalation in humans and animals, results in irri...		Others
T0976	Propoxur	Aprocarb,Propoxure,Baygon	AChR , Antifungal
	Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red b...		AChR , Antifungal
T4867	Erucic acid	Prifac 2990,13(Z)-Docosenoic Acid,cis-13-docosenoic acid	PI3K , Endogenous Metabolite
	Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ). Erucic acid (13(Z)-Docosenoic Acid) is broken down long-chain...		PI3K , Endogenous Metabolite
T4716	Pyrrole-2-carboxylic acid	2-Pyrrolecarboxylic acid,Minaline	Endogenous Metabolite
	Pyrrole-2-carboxylic acid (Minaline) was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxidase. The latter rela...		Endogenous Metabolite
T4776	Glycerol	Glycerin	Endogenous Metabolite
	Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol...		Endogenous Metabolite
T34949	Trimethylolpropane caprate	UNII-X307CM75YF,Trimethylolpropane tridecanoate,Trimethylolpropane tricaprate
	Trimethylolpropane caprate has developmental toxicity in Sprague-Dawley rats.
T12640	(R,R)-Glycopyrrolate	(R,R)-Glycopyrronium bromide,(R,R)-Glycopyrrolate bromide	Others
	(R,R)-Glycopyrrolate is an agent of anticholinergic, has the ability to reduce the frequency of drooling in vivo with developmental disabilities.		Others
T14963	CI-943	(±)-CI-943	Others
	CI-943 is a novel potential antipsychotic drug that does not bind to dopamine (DA) receptors and has some developmental neurotoxicity.		Others
T61592	Thalidomide-piperazine hydrochloride
	Thalidomide-piperazine hydrochloride is a chemical compound with potential applications in the research of leprosy and multiple myeloma. It serves as a valuable tool in developmental biology, facilitating significant dis...
T29886	Almestrone	BA-38372,BA 38372,Ciba-38372,BA38372,Ciba 38372
	Almestrone (developmental code names Ba 38372, Ciba 38372), also known as 7α-methylestrone, is a synthetic, steroidal estrogen which was synthesized in 1967 but was never marketed. It is used as a precursor in the synthe...
T36092	Fenobucarb
	Fenobucarb, a widely employed carbamate insecticide, poses potential risks to the cardiovascular and cerebrovascular systems in animals[1][2]. It triggers developmental neurotoxicity in zebrafish by engaging pathways rel...