cough — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5S0691	Shionone	Shionon	Others
	1. Shionone (Shionon) has anti-tussive and anti-inflammatory effects.		Others
T9353	OXOMEMAZINE		AChR , Histamine Receptor
	Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic activity. Oxomemazine is a selective antagonist of mycotoxins M1 receptors, showing high (Ki=84 nM, M1 receptors) and low ...		AChR , Histamine Receptor
T9519	Eliapixant	BAY 1817080	P2X Receptor
	Eliapixant (BAY 1817080) (BAY 1817080) is a potent and selective P2X3 receptor antagonist, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.		P2X Receptor
T0739	Guaifenesin	Glycerol guaiacolate,Guaiacol glyceryl ether,Guaiphenesin	Others
	Guaifenesin (Guaiphenesin) is an expectorant that also has some muscle relaxing action. It is used in many cough preparations.		Others
T0828	Bromhexine hydrochloride	Bromhexine HCl,Auxit,Bisolvon	SARS-CoV , HIV Protease , Autophagy
	Bromhexine hydrochloride (Bisolvon) is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.		SARS-CoV , HIV Protease , Autophagy
T5S0106	Peimisine	Ebeiensine	RAAS , AChR
	1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe...		RAAS , AChR
T5099	Gefapixant	RO 4926219,AF219,MK-7264	P2X Receptor
	Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.		P2X Receptor
T3267	Potassium guaiacolsulfonate hemihydrate	Potassium guaiacolsulfonate,Potassium 4-guaiacolsulfonate hemihydrate	Antibacterial , Antibiotic
	Potassium guaiacolsulfonate hemihydrate (Potassium guaiacolsulfonate) is an aromatic sulfonic acid used in medicine as an expectorant.		Antibacterial , Antibiotic
T5007	Benproperine phosphate	Blascorid,Pirexyl phosphate	Others , Microtubule Associated
	Benproperine phosphate (Pirexyl phosphate) is a cough suppressant.		Others , Microtubule Associated
T0768	Oxolamine citrate	AF-438 citrate,SKF-9976 citrate	Others
	Oxolamine citrate (AF-438 citrate) is a cough suppressant that is able to be used as a generic drug in many jurisdictions.		Others
T8333	Aurintricarboxylic acid	ATA,NSC-4056,NSC4056,NSC 4056	Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase
	Aurintricarboxylic acid (NSC-4056) is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme.		Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase
T0284	Sulfogaiacol	guaiacolsulfonate	Others , Antibacterial
	Sulfogaiacol (guaiacolsulfonate) is an antitussive agent, used for acute respiratory tract infections and cough.		Others , Antibacterial
T12489L	Pimethixene maleate	Pimetixene maleate	Dopamine Receptor , 5-HT Receptor , AChR , Histamine Receptor
	Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as we...
T28728	SCH-486757
	SCH-486757, a nociceptin receptor (NOP) agonist, is used potentially for the treatment of cough.
T3370	Hederacoside C	Kalopanaxsaponin B,Hederasaponin C	Others , Antibacterial
	Hederacoside C (Hederasaponin C) is expectorant for Cold and cough relief, Bronchitis.		Others , Antibacterial
T0452	Dropropizine	(±)-Dropropizine,UCB-196,UCB-1967	Others
	Dropropizine (UCB-1967), a racemic non-opiate antitussive agent, is served as a cough suppressant.		Others
T0464	Carbetapentane citrate	Pentoxyverine citrate	AChR
	Carbetapentane citrate (Pentoxyverine citrate) , an antitussive (cough suppressant), is frequently used for a cough related to illnesses like the common cold.		AChR
T0576	Diethylaminoethoxyethanol		Others
	Diethylaminoethoxyethanol is served in the production of cough medicine Toclase and so on.		Others
T0217L	(+)-Dropropizine	(+)-Dropropizine	Histamine Receptor
	(+)-Dropropizine can inhibit histamine receptor, anti-allergic, and reduce a cough by modulation of neuropeptides involved in the cough reflex and by interfering with stimulus activation of peripheral endings of sensory ...		Histamine Receptor
T0056	Oxeladin citrate		Others
	Oxeladin citrate is a highly potent and effective cough suppressant, which can treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment with oxeladin is no risk of add...		Others