Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2, and can be used in studies of dry and irritant cough in children. irritant cough in children.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 30.00 | |
10 mg | In stock | $ 48.00 | |
25 mg | In stock | $ 77.00 | |
50 mg | In stock | Inquiry | |
1 mL * 10 mM (in DMSO) | In stock | $ 53.00 |
Description | Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2, and can be used in studies of dry and irritant cough in children. irritant cough in children. |
Targets&IC50 | 5-HT2A receptor:10.22 (pKi), M2 mAChR:9.38 (pKi), 5-HT2C receptor:8.42 (pKi), 5-HT2B receptor:10.44 (pKi), H1 receptor:10.14 (pKi), DD4.4 receptor:7.54 (pKi), 5-HT1A receptor:7.63 (pKi), D2 receptor:8.19 (pKi), M1 receptor:8.61 (pKi) |
Synonyms | Pimetixene maleate |
Molecular Weight | 409.5 |
Formula | C23H23NO4S |
CAS No. | 13187-06-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (195.36 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Pimethixene maleate 13187-06-9 GPCR/G Protein Immunology/Inflammation Neuroscience Dopamine Receptor 5-HT Receptor AChR Histamine Receptor Pimetixene maleate inhibitor inhibit