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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0386L | Ropivacaine | LEA-103 HCl | Potassium Channel , Sodium Channel |
Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group. | |||
T0386 | Ropivacaine hydrochloride | Ropivacaine monohydrochloride | Potassium Channel , Sodium Channel |
Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity. | |||
T6645 | Ropivacaine hydrochloride monohydrate | Ropivacaine HCl,Ropivacaine HCl monohydrate,LEA 103,LEA-103 HCl | Potassium Channel , Sodium Channel |
Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly. | |||
T15756 | Lidorestat | IDD-676 | Reductase |
Lidorestat (IDD-676) is an aldose reductase inhibitor (IC50: 5 nM) with effective, selective and oral activity. Lidorestat improves nerve conduction and reduces the formation of cataracts. Lidorestat can be used to treat... | |||
T6476 | Dofetilide | UK 68789,UK-68798,Tikosyn | Potassium Channel |
Dofetilide (UK 68789) is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ik... | |||
T0030 | Bupivacaine hydrochloride | Vivacaine,Bupivacaine HCl | Sodium Channel |
Bupivacaine hydrochloride (Vivacaine) is a long-acting, amide-type local anesthetic. Bupivacaine hydrochloride reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the vol... | |||
T0802 | Procaine hydrochloride | Novocaine HCl,Procaine HCl | Histone Demethylase , 5-HT Receptor , DNA/RNA Synthesis , Sodium Channel , NMDAR , AChR |
Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannel... | |||
T6541 | Ibutilide Fumarate | Corvert Fumarate,U70226E | Calcium Channel , Sodium Channel |
Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outwar... | |||
T15257 | Etripamil | MSP-2017,(-)-MSP-2017 | Calcium Channel |
Etripamil (MSP-2017) displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells... | |||
T9857 | Vasopressin | antidiuretic hormone (ADH),argipressin,arginine vasopressin (AVP) | Endogenous Metabolite |
Vasopressin (argipressin), a cyclic nine-peptide synthesized by hypothalamic neurons, is one of the hormones involved in peptide prohormone synthesis. Vasopressin is involved in the regulation process of hypothalamic-pit... | |||
T68252 | Mesotrin | ||
Mesotrin is a calcium antagonist that influences atrial and ventricular conduction, but has been linked with side effects of euphoria, ventigo and heavyheadedness. | |||
T69144 | Hexylcaine HCl | ||
Hexylcaine HCl also called cyclaine or osmocaine, is a short-acting local anesthetic. It acts by inhibiting sodium channel conduction. Overdose can lead to headache, tinnitus, numbness and tingling around the mouth and t... | |||
T26230 | Stilbamidine dihydrochloride | NSC 35605,NCI 174 | |
Stilbamidine dihydrochloride is a blocker of neuromuscular transmission and axonal conduction used to study the distribution of the drug in the organs and tissues of rats following intravenous injection. | |||
T31119 | CVT-2759 | UNII-42E8N8RC9Z,CVT2759 | |
CVT-2759 is A potential partial agonist for A(1)-ADORs, and it may be useful to slow atrioventricular node conduction to reduce ventricular rate without causing the atrioventricular block, bradycardia, atrial arrhythmias... | |||
T24623 | PF-06807656 | PF 06807656 | |
PF-06807656 is insensitive to the introduction of the N171D mutation in the ROMK conduction pore that greatly diminishes the activity of other small-molecule inhibitors. PF-06807656 is an effective ROMK inhibitor (Tl+ fl... | |||
TN4616 | N-Methyltaxol C | Others | |
N-methyltaxol C and paclitaxel can produce a positive inotropic effect in papillary muscle, without alterations in the action potential. They can induced conduction arrhythmias and reduce coronary flow and left ventricul... | |||
T71559 | Melanotan II acetate | ||
Melanotan II acetate is an agonist of melanocortin receptor 1 (MC1R), MC3R, MC4R, and MC5R. It has been shown to improve recovery of sciatic nerve function after mechanical injury and increase cisplatin-induced decreases... | |||
T82567 | Di-4-ANEPPS | ||
Di-4-ANEPPS, a voltage-sensitive dye, is utilized for detecting membrane potential changes, offering a time resolution under 1 ms and fluorescence variations up to 10% per 100 mV. Widely used for cardiac electrical activ... | |||
T71228 | Adaprolol maleate | ||
Adaprolol maleate is a beta-blocker and opthalmic which may be used in the treatment of Glaucoma or other ailments of the eye. Adaprolol has marked electrophysiologic effects. Its major action was on sinus node; it prolo... | |||
T61475 | Ropivacaine mesylate | ||
Ropivacaine mesylate, a long-acting amide local anaesthetic, is used for spinal block and effectively mitigates neuropathic pain. It achieves analgesia by reversibly inhibiting sodium ion influx in nerve fibers, thus blo... |