Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Lidorestat (IDD-676) is an aldose reductase inhibitor (IC50: 5 nM) with effective, selective and oral activity. Lidorestat improves nerve conduction and reduces the formation of cataracts. Lidorestat can be used to treat complications of chronic diabetes.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 42.00 | |
10 mg | In stock | $ 66.00 | |
50 mg | In stock | $ 197.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 46.00 |
Description | Lidorestat (IDD-676) is an aldose reductase inhibitor (IC50: 5 nM) with effective, selective and oral activity. Lidorestat improves nerve conduction and reduces the formation of cataracts. Lidorestat can be used to treat complications of chronic diabetes. |
Targets&IC50 | Rldose reductase:5 nM |
In vivo | Lidorestat (25 mg/kg/day; oral administration; twice daily; 6 weeks) in diabetic mice results in reduced fructose levels and lower mortality rates in hAR-expressing mice. And Lidorestat does not affect weight.[1] |
Synonyms | IDD-676 |
Molecular Weight | 376.35 |
Formula | C18H11F3N2O2S |
CAS No. | 245116-90-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45.0 mg/mL (119.6 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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Lidorestat 245116-90-9 Endocrinology/Hormones Metabolism Reductase IDD676 IDD-676 IDD 676 inhibitor inhibit