coagulation — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP2234	coagulation factor II (thrombin) B chain fragment [Homo sapiens]		Others
	Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a ser...		Others
T81655	Nonacog alfa	BAX326,Coagulation Factor IX [Recombinant]
	Nonacog alfa (BAX326), a recombinant human factor IX, is utilized in the study of hemophilia B [1].
T4502	BISMUTH SUBGALLATE	Dermatol Puder,Bismuth Gallate	Others
	Bismuth subgallate (Dermatol Puder) is an astringent and antiseptic and is applied to skin diseases such as eczema.		Others
T67853	Rivaroxaban Impurity	Rivaroxaban-10	Factor Xa
	Rivaroxaban Impurity (Rivaroxaban-10) is a potent Blood-coagulation factor Xa inhibitor, IC50= 66 nM.		Factor Xa
T19603	Vitamin K	Kephton,Vitamin K1(20)	Endogenous Metabolite
	Vitamin K (Kephton) has blood coagulation action and is important for coagulation factors, matrix-Gla protein, and osteocalcin.		Endogenous Metabolite
T27920	LY 517717	LY-517717,LY517717	Factor Xa
	LY 517717 is an orally active inhibitor of coagulation factor Xa with antithrombotic activity for the study of venous thromboembolism (VTE).		Factor Xa
T2570	Vitamin K4	Kapilin,Menadiol Diacetate,acetomenaphthone	Apoptosis , Endogenous Metabolite
	Vitamin K4 (Menadiol Diacetate) is a vitamin medicine for the treatment of blood coagulation disorders that caused by the lack of VK4.		Apoptosis , Endogenous Metabolite
T11012	Dextran	Dextran 40	Platelet aggregation
	Dextran has an inhibitory effect on platelet aggregation and coagulation factors, and is used as an agent for increasing plasma volume.		Platelet aggregation
T3469	PCI-27483	PCI27483	Others
	PCI-27483 is an activated coagulation factor VIIa inhibitor with antithrombotic effects in a baboon model of arterial thrombosis. It also inhibits the growth of BxPC3 xenografts by 42% and 85% at doses of 60 and 90 mg/kg...		Others
T7674	Thrombin Receptor Activator for Peptide		Protease-activated Receptor
	Thrombin Receptor Activator for Peptide is also called Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), used in the research of coronary heart disease (CHD).		Protease-activated Receptor
T83969	Casein		Hydroxylase
	Casein is a milk protein with multiple roles in a novel drug delivery system that affects postprandial amino acid delivery in different ways through its intragastric coagulation properties.		Hydroxylase
T13693	Fibrin		Others
	Fibrin, the primary constituent of blood clots, is an insoluble protein essential for coagulation. Isolated from bovine blood, this protein is notably synthesized in response to bleeding.		Others
T4S1658	Benzoyloxypaeoniflorin	Benzoyloxypeoniflorin	NF-κB , Tyrosinase
	Benzoyloxypaeoniflorin (Benzoyloxypeoniflorin) is a natural product,contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coagulation.		NF-κB , Tyrosinase
T0372	Gabexate mesylate	FOY	Factor Xa , Serine Protease , Proteasome
	Gabexate mesylate (FOY) is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inh...		Factor Xa , Serine Protease , Proteasome
T5968	DL-Homocysteine thiolactone hydrochloride	DL-Homocysteinethiolactone hydrochloride	Endogenous Metabolite
	DL-Homocysteine thiolactone hydrochloride (DL-Homocysteinethiolactone hydrochloride) is a cysteine derivative that binds to and induces conformational changes in various plasma proteins, slowing coagulation and inducing ...		Endogenous Metabolite
T1736	Apixaban	BMS-562247-01	Factor Xa
	Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and pr...		Factor Xa
TL0001	Dencichine	L-Dencichin,ODAP,Dencichin	Others , HIF/HIF Prolyl-Hydroxylase
	Dencichine (ODAP) is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic system. It has renoprotective effec...		Others , HIF/HIF Prolyl-Hydroxylase
T66256	Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate		Factor Xa
	Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate has an inhibitory effect on coagulation factor Xa, and it can be used in the study of thrombop...		Factor Xa
T1184	Rivaroxaban	BAY 59-7939	Factor Xa , Thrombin
	Rivaroxaban (BAY 59-7939) is an orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administration, rivaroxaban selectively binds to both ...		Factor Xa , Thrombin
T11994	Melagatran		Thrombin
	Melagatran, a direct and orally active thrombin inhibitor, specifically inhibits thrombin without affecting other enzymes in the coagulation cascade or fibrinolytic enzymes. It does not rely on endogenous co-factors to e...		Thrombin