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Search Results for " arachidonic "

20

Compounds

Cat No. Product Name Synonyms Targets
T4129 Arachidonic acid Immunocytophyte,arachidonate,Immunocytophyt,Vevodar Others , Endogenous Metabolite
Arachidonic acid (Immunocytophyte) is an unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is for...
T14021 20-HETE 20-hydroxy Arachidonic Acid Others
20-HETE (20-hydroxy Arachidonic Acid) is a CYP450 metabolite and a potent vasoconstrictor and it is an endogenous inhibitor of the large-conductance Ca2+-activated K+ channel in renal arterioles. 20-HETE increases NADPH ...
T38070 Arachidonic Acid-biotin
Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient, critical substrate f...
T22581 Arachidonic Acid Leelamide Others
Arachidonic acid leelamide is a phospholipase A2 inhibitor. Phospholipase A is a hydrolase responsible for the release of arachidonic acid from the sn2 position of phospholipids. The released arachidonic acid is then con...
T38067 5,6-dehydro Arachidonic Acid
5,6-dehydro Arachidonic acid is an analog of arachidonic acid with an acetylene in the 5,6 position. It inhibits 5-LO in rat basophilic leukemia cells, with a Ki value of 15 μM. In guinea pig leukocytes, 5-LO is inhibite...
T36232 20-carboxy Arachidonic Acid
20-carboxy Arachidonic acid (20-COOH-AA) is the major metabolite of 20-HETE that is produced in renal tubular epithelial, endothelial, and microvascular smooth muscle cell cultures. This ω-oxidation conversion can take p...
T81609 Omega-3 Arachidonic acid ethyl ester (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester,ω-3 Arachidonic acid ethyl ester
Omega-3 Arachidonic Acid ethyl ester, a rare polyunsaturated fatty acid with limited presence in dietary sources, is crucial for infant growth and development and offers protection against heart disease, blood clots, hig...
T21815 ONO-RS-082 Others
ONO-RS-082 is a Ca2+-independent phospholipase A2 inhibitor.
T2367 SKF-86002 SKF86002 p38 MAPK , TNF
SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).
T0412 Idebenone CV-2619 Apoptosis , Antioxidant , Mitochondrial Metabolism
Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).
T4P2931 Linoleic acid 9,12-octadecadienoic acid,acidelinoleique,9,12-Linoleic acid Others , Endogenous Metabolite
Linoleic acid (9,12-octadecadienoic acid) is an essential fatty acid. Prostaglandin precursor.
T27026 CJ-13,610 CJ 13610,CJ-13610 Lipoxygenase
CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expression of IL-6 mRNA in macrophages.
T62606 ALOX15-IN-2 Lipoxygenase
ALOX15-IN-2 is a potent inhibitor of ALOX15 linoleate oxygenase activity, inhibiting the oxidation of linoleic acid (LA) and arachidonic acid (AA), the immediate homologs of ALOX15, with IC50s of 1.55 and 2.79 μM, respec...
T13632 D-Erythro-dihydrosphingosine Dihydrosphingosine,Octadecasphinganine,C18-Dihydrosphingosine,D-erythro-Sphinganine Phospholipase , Endogenous Metabolite
D-Erythro-dihydrosphingosine (C18-Dihydrosphingosine) inhibits arachidonic acid release and cPLA2α activity.
TN1643 Ferulamide 4-Hydroxy-3-methoxycinnamide PAFR , AChR
Ferulamide (4-Hydroxy-3-methoxycinnamide), a Ferulic acid derivative, shows potent inhibitory activity against arachidonic acid-induced platelet aggregation.
T70188 ER-34122 Lipoxygenase
ER-34122, a novel orally available dual 5-lipoxygenase/cyclooxygenase inhibitor, exhibits potent anti-inflammatory activity in an arachidonic acid-induced ear inflammation model.
T60061 RU-TRAAK-2 Potassium Channel
RU-TRAAK-2 is a reversible inhibitor of TWIK-related arachidonic acid-stimulated K+ channel with no activity for non-K2P channels including Kv1.2, GIRK2, and Slo1.
T0961 Trometamol Tromethamine COX
Trometamol (Tromethamine) is a proton acceptor used to treat acidemia. It inhibits both isoforms of cyclooxygenases (COX1 and COX2), thereby blocking the conversion of arachidonic acid to pro-inflammatory pro-prostagland...
T1420 Diethylcarbamazine citrate Caritrol,Loxuran,Dicarocide Lipoxygenase , COX , Parasite
Diethylcarbamazine citrate (Caritrol) is an anthelmintic used primarily as the citrate in the treatment of filariasis, particular infestations with Wucheria bancrofti or Loa loa. It is an inhibitor of arachidonic acid me...
TN1873 Lirinidine Others
(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, a...

Compounds

Arachidonic acid
T4129
Synonym: Immunocytophyte,arachidonate,Immunocytophyt,Vevodar
Target: Others, Endogenous Metabolite
20-HETE
T14021
Synonym: 20-hydroxy Arachidonic Acid
Target: Others
Arachidonic Acid-biotin
T38070
Synonym:
Target:
Arachidonic Acid Leelamide
T22581
Synonym:
Target: Others
5,6-dehydro Arachidonic Acid
T38067
Synonym:
Target:
20-carboxy Arachidonic Acid
T36232
Synonym:
Target:
omega-3 Arachidonic acid ethyl ester
T81609
Synonym: (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester,ω-3 Arachidonic acid ethyl ester
Target:
ONO-RS-082
T21815
Synonym:
Target: Others
SKF-86002
T2367
Synonym: SKF86002
Target: p38 MAPK, TNF
Idebenone
T0412
Synonym: CV-2619
Target: Apoptosis, Antioxidant, Mitochondrial Metabolism
Linoleic acid
T4P2931
Synonym: 9,12-octadecadienoic acid,acidelinoleique,9,12-Linoleic acid
Target: Others, Endogenous Metabolite
CJ-13,610
T27026
Synonym: CJ 13610,CJ-13610
Target: Lipoxygenase
ALOX15-IN-2
T62606
Synonym:
Target: Lipoxygenase
D-Erythro-dihydrosphingosine
T13632
Synonym: Dihydrosphingosine,Octadecasphinganine,C18-Dihydrosphingosine,D-erythro-Sphinganine
Target: Phospholipase, Endogenous Metabolite
Ferulamide
TN1643
Synonym: 4-Hydroxy-3-methoxycinnamide
Target: PAFR, AChR
ER-34122
T70188
Synonym:
Target: Lipoxygenase
RU-TRAAK-2
T60061
Synonym:
Target: Potassium Channel
Trometamol
T0961
Synonym: Tromethamine
Target: COX
Diethylcarbamazine citrate
T1420
Synonym: Caritrol,Loxuran,Dicarocide
Target: Lipoxygenase, COX, Parasite
Lirinidine
TN1873
Synonym:
Target: Others
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TargetMol