antidepressants — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0084	Moclobemide	Ro111163	MAO , Monoamine Oxidase
	Moclobemide (Ro111163) is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.		MAO , Monoamine Oxidase
T1045	Trimipramine maleate	Surmontil maleate	Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Norepinephrine , Histamine Receptor
	Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Mal...
T20025	Imipramine	Melipramine,HSDB3100,HSDB 3100,Dimipressin,HSDB-3100
	Imipramine is an agent of tricyclic antidepressants.
T0172	Maprotiline hydrochloride	Maprotiline HCl,Psymion,Deprilept,Ludiomil	5-HT Receptor , Adrenergic Receptor , AChR , Norepinephrine , Autophagy , Histamine Receptor
	Maprotiline hydrochloride (Psymion) is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.
T0450L	Fluoxetine hydrochloride	Fluoxetine HCl,LY-110140,Lilly110140	5-HT Receptor , Serotonin Transporter , Autophagy
	Fluoxetine hydrochloride (Lilly110140) is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.		5-HT Receptor , Serotonin Transporter , Autophagy
T0185	Escitalopram	Seroplex,S-(+)-Citalopram,(S)-Citalopram	Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor
	Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patien...
T0943	Carbamazepine	NSC 169864	Mitophagy , Sodium Channel , Autophagy
	Carbamazepine (NSC-169864) is a tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing polysyna...		Mitophagy , Sodium Channel , Autophagy
T23628	AD-2646	AD2646
	AD-2646 is a new quinoline derivative. It also has similar pharmacological properties to tricyclic antidepressants.
T31604	Edivoxetine	LY-2216684,LY 2216684,LY2216684
	Edivoxetine( LY2216684) is a selective norepinephrine reuptake inhibitor being developed as a treatment for attention deficit hyperactivity disorder (ADHD) and antidepressants.
T25047	Alfetamine	alpha-allyl-phenethylamine
	Alfetamine is a chemical compound of the phenethylamine family. It is similar to imipramine and amitriptyline, two tricyclic antidepressants.
T68327	Dexnafenodone Free Base
	Dexnafenodone Free Base is a potent inhibitor of noradrenaline, and to a lesser degree of serotonin reuptake, induced changes in the pattern of sleep which are comparable to those of non‐sedating tricyclic antidepressant...
T37307	Nordoxepin hydrochloride
	Doxepin is a tricyclic antidepressant. Desmethyldoxepin is the primary metabolite of doxepin, produced by metabolism at the liver. The metabolism of tricyclic antidepressants, including doxepin, is affected by a variety ...
T69943	Citalopram oxalate
	Citalopram oxalate is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients wh...
T60265	NV-5138 hydrochloride
	NV-5138 hydrochloride is a leucine analog and is the first selective and orally active brain mTORC1 activator, binding to Sestrin2. NV-5138 hydrochloride can be used in the research of antidepressants [1] [2].