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Search Results for " vn "

Targets

25

Compounds

8

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6509 Galeterone VN-124-1,TOK-001,VN/124-1,VN 124 P450 , Androgen Receptor
Galeterone (VN 124) is an orally bioavailable small-molecule androgen receptor modulator and CYP17 lyase inhibitor with potential antiandrogen activity. Galeterone exhibits three distinct mechanisms of action: 1) as an a...
T1979 AVN-944 VX-944 Dehydrogenase
AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
T9346 CVN424 GPR
CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.
T5179 AVN-492 AVN492 5-HT Receptor
AVN-49 is a potent and selective 5-HT6R Antagonist (Ki: 91 pM).
T26690 AVN-101 5-HT Receptor , Adrenergic Receptor , Histamine Receptor
AVN-101 is a potent 5-HT7 receptor antagonist.
T9787 Suvn-911 AChR
suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.
T39218 (S)-CVN424 (S)-CVN424
(S)-CVN424 is a powerful modulator of G-Protein-Coupled Receptor 6 (GPR6), known for its involvement in neurological and psychiatric disorders research, such as Parkinson's disease.
T81836 Mca-SEVNLDAEFK(Dnp)-NH2
Mca-SEVNLDAEFK(Dnp)-NH2 is a fluorogenic substrate featuring a 7-methoxycoumarin moiety whose fluorescence is quenched by the adjacent 2,4-dinitrophenyl group through resonance energy transfer. This compound serves as a ...
TP1505 MCA-SEVNLDAEFR-K(Dnp)-RR, amide
MCA-SEVNLDAEFR-K(Dnp)-RR, amide is a FRET-based substrate.
T71593 AVN-101 free base
AVN-101 is a very potent 5-HT7 receptor antagonist, with slightly lesser potency toward 5-HT6, 5-HT2A, and 5HT-2C receptors. It is a multi-target drug candidate for the treatment of CNS disorders.
T78007 Vasonatrin Peptide (VNP) TFA
Vasonatrin Peptide (VNP) TFA, a chimeric compound derived from atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP), exhibits venodilating properties reminiscent of CNP, natriuretic effects akin to ANP, ...
T80128 RE(EDANS)EVNLDAEFK(DABCYL)R Beta-Secretase
RE (EDANS) EVNLDAEFK (DABCYL) R is a double-labeled peptide with EDANS and DABCYL, functioning as a fluorescent substrate for BACE1 with an emission wavelength of 360 nm and an excitation wavelength of 528 nm. Its utilit...
T83848 VnP-16 TFA
VnP-16, a synthetic peptide fragment mirroring amino acids 270-281 of vitronectin (a multifunctional glycoprotein involved in cell attachment, migration, and spreading), promotes attachment and spreading of isolated huma...
T76562 VLVNTFCDSCIPKTYWNLGY TFA
VLVNTFCDSCIPKTYWNLGY TFA, an antigenic peptide of the M3 muscarinic receptor (M3R), is utilized in Enzyme-Linked Immunosorbent Assay (ELISA) [1].
TP1872 Vasonatrin Peptide (VNP) Vasonatrin Peptide VNP
Vasonatrin peptide (VNP) is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP) with potent venodilating and natriuretic activity.
T28008 MDVN1003 MDVN 1003,MDVN-1003
MDVN1003 is a potent inhibitor of BTK amd PI3Kδ, two proteins regulated by the B cell receptor (BCR) that drive the growth of many NHLs. MDVN1003 induces cell death in a B cell lymphoma cell line but not in an irrelevant...
T30230 AVN-211 CD-008-0173,AVN 211
AVN-211 (CD-008-0173) is a novel and highly selective 5-HT6 receptor small molecule antagonist for the treatment of Alzheimer's disease.
T17251 VNA-932 WAY-VNA 932 Others
VNA-932 is an agonist of the vasopressin V2-receptor (IC50: 80.3 nM and 778 nM in human-V2 binding and V1a binding assay).
T83686 Mca-SEVNLDAEFR-K(Dnp)-RR-NH2 acetate
Mca-SEVNLDAEFR-K(Dnp)-RR-NH2 is a fluorogenic substrate designed for the quantification of β-secretase (BACE) activity. When cleaved by BACE, it liberates 7-methoxycoumarin-4-acetyl (Mca), a compound whose fluorescence, ...
T80529 VnP-16 Integrin
VnP-16 enhances bone formation by stimulating the differentiation and activity of osteoblasts via direct β1 integrin engagement, which subsequently activates FAK [1].
T78090 CVN636
CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for human mGluR7.
T78827 CVN417
CVN417 is an orally active antagonist of nAChR containing the α6 subunit, modulating phasic dopaminergic neurotransmission in an impulse-dependent fashion. It inhibits Ca(2+) efflux through nAChR subunits, displaying IC5...
T26691 AVN-322 AVN 322
AVN-322 is a 5-HT6 receptor antagonist. 5-HT6R antagonists improves cognition in animal models of cognitive impairment.
T126173 Gypenoside VN3
Gypenoside VN3 is a useful organic compound for research related to life sciences. The catalog number is T126173 and the CAS number is 1235721-51-3.
T24942 VNRX-5133 VNRX 5133
VNRX-5133 is an injectable broad-spectrum β-lactamase inhibitor. VNRX-5133 is a novel β-lactamase inhibitor with potent and selective direct inhibitory activity against both serines- and Metallo-β-lactamases.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01861 Vitronectin Protein, Mouse, Recombinant (His) Mouse HEK293
Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exis...
TMPY-00121 Vitronectin Protein, Human, Recombinant (His) Human HEK293
Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exis...
TMPJ-00472 Vitronectin Protein, Human, Recombinant (Truncated, His) Human Human Cells
Vitronectin, also known as VTN, is a large glycoprotein found in blood and the extracellular matrix (ECM). Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood ...
TMPY-01403 VNN1 Protein, Human, Recombinant (His) Human HEK293
Pantetheinase, also known as Pantetheine hydrolase, Vascular non-inflammatory molecule 1, Vanin-1, and VNN1, is a cell membrane protein which belongs to the CN hydrolase family and BTD/VNN subfamily. Vanin-1 contains one...
TMPY-02529 VNN1 Protein, Mouse, Recombinant (His) Mouse HEK293
Pantetheinase, also known as Pantetheine hydrolase, Vascular non-inflammatory molecule 1, Vanin-1, and VNN1, is a cell membrane protein which belongs to the CN hydrolase family and BTD/VNN subfamily. Vanin-1 contains one...
TMPY-01614 VNN2 Protein, Human, Recombinant (His) Human HEK293
Vascular non-inflammatory molecule 2, also known as glycosyl-phosphatidyl inositol-anchored protein GPI-8, Vanin-2, Protein FOAP-4 and VNN2, is a cell membrane protein that belongs to the CN hydrolase family and Vanin su...
TMPY-05937 Influenza A H1N1 (A/Sw/Bulnes/VN1401-P6SP/2018) Neuraminidase/NA Protein (His) H1N1 HEK293
Neuraminidases are enzymes that cleave sialic acid groups from glycoproteins. Influenza neuraminidase is a type of neuraminidase found on the surface of influenza viruses that enables the virus to be released from the ho...
TMPY-02730 VNN1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Pantetheinase, also known as Pantetheine hydrolase, Vascular non-inflammatory molecule 1, Vanin-1, and VNN1, is a cell membrane protein which belongs to the CN hydrolase family and BTD/VNN subfamily. Vanin-1 contains one...
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