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Cat No. | Product Name | Synonyms | Targets |
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T6509 | Galeterone | VN-124-1,TOK-001,VN/124-1,VN 124 | P450 , Androgen Receptor |
Galeterone (VN 124) is an orally bioavailable small-molecule androgen receptor modulator and CYP17 lyase inhibitor with potential antiandrogen activity. Galeterone exhibits three distinct mechanisms of action: 1) as an a... | |||
T1979 | AVN-944 | VX-944 | Dehydrogenase |
AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2. | |||
T9346 | CVN424 | GPR | |
CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease. | |||
T5179 | AVN-492 | AVN492 | 5-HT Receptor |
AVN-49 is a potent and selective 5-HT6R Antagonist (Ki: 91 pM). | |||
T26690 | AVN-101 | 5-HT Receptor , Adrenergic Receptor , Histamine Receptor | |
AVN-101 is a potent 5-HT7 receptor antagonist. | |||
T9787 | Suvn-911 | AChR | |
suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity. | |||
T39218 | (S)-CVN424 | (S)-CVN424 | |
(S)-CVN424 is a powerful modulator of G-Protein-Coupled Receptor 6 (GPR6), known for its involvement in neurological and psychiatric disorders research, such as Parkinson's disease. | |||
T81836 | Mca-SEVNLDAEFK(Dnp)-NH2 | ||
Mca-SEVNLDAEFK(Dnp)-NH2 is a fluorogenic substrate featuring a 7-methoxycoumarin moiety whose fluorescence is quenched by the adjacent 2,4-dinitrophenyl group through resonance energy transfer. This compound serves as a ... | |||
TP1505 | MCA-SEVNLDAEFR-K(Dnp)-RR, amide | ||
MCA-SEVNLDAEFR-K(Dnp)-RR, amide is a FRET-based substrate. | |||
T71593 | AVN-101 free base | ||
AVN-101 is a very potent 5-HT7 receptor antagonist, with slightly lesser potency toward 5-HT6, 5-HT2A, and 5HT-2C receptors. It is a multi-target drug candidate for the treatment of CNS disorders. | |||
T78007 | Vasonatrin Peptide (VNP) TFA | ||
Vasonatrin Peptide (VNP) TFA, a chimeric compound derived from atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP), exhibits venodilating properties reminiscent of CNP, natriuretic effects akin to ANP, ... | |||
T80128 | RE(EDANS)EVNLDAEFK(DABCYL)R | Beta-Secretase | |
RE (EDANS) EVNLDAEFK (DABCYL) R is a double-labeled peptide with EDANS and DABCYL, functioning as a fluorescent substrate for BACE1 with an emission wavelength of 360 nm and an excitation wavelength of 528 nm. Its utilit... | |||
T83848 | VnP-16 TFA | ||
VnP-16, a synthetic peptide fragment mirroring amino acids 270-281 of vitronectin (a multifunctional glycoprotein involved in cell attachment, migration, and spreading), promotes attachment and spreading of isolated huma... | |||
T76562 | VLVNTFCDSCIPKTYWNLGY TFA | ||
VLVNTFCDSCIPKTYWNLGY TFA, an antigenic peptide of the M3 muscarinic receptor (M3R), is utilized in Enzyme-Linked Immunosorbent Assay (ELISA) [1]. | |||
TP1872 | Vasonatrin Peptide (VNP) | Vasonatrin Peptide VNP | |
Vasonatrin peptide (VNP) is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP) with potent venodilating and natriuretic activity. | |||
T28008 | MDVN1003 | MDVN 1003,MDVN-1003 | |
MDVN1003 is a potent inhibitor of BTK amd PI3Kδ, two proteins regulated by the B cell receptor (BCR) that drive the growth of many NHLs. MDVN1003 induces cell death in a B cell lymphoma cell line but not in an irrelevant... | |||
T30230 | AVN-211 | CD-008-0173,AVN 211 | |
AVN-211 (CD-008-0173) is a novel and highly selective 5-HT6 receptor small molecule antagonist for the treatment of Alzheimer's disease. | |||
T17251 | VNA-932 | WAY-VNA 932 | Others |
VNA-932 is an agonist of the vasopressin V2-receptor (IC50: 80.3 nM and 778 nM in human-V2 binding and V1a binding assay). | |||
T83686 | Mca-SEVNLDAEFR-K(Dnp)-RR-NH2 acetate | ||
Mca-SEVNLDAEFR-K(Dnp)-RR-NH2 is a fluorogenic substrate designed for the quantification of β-secretase (BACE) activity. When cleaved by BACE, it liberates 7-methoxycoumarin-4-acetyl (Mca), a compound whose fluorescence, ... | |||
T80529 | VnP-16 | Integrin | |
VnP-16 enhances bone formation by stimulating the differentiation and activity of osteoblasts via direct β1 integrin engagement, which subsequently activates FAK [1]. | |||
T78090 | CVN636 | ||
CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for human mGluR7. | |||
T78827 | CVN417 | ||
CVN417 is an orally active antagonist of nAChR containing the α6 subunit, modulating phasic dopaminergic neurotransmission in an impulse-dependent fashion. It inhibits Ca(2+) efflux through nAChR subunits, displaying IC5... | |||
T26691 | AVN-322 | AVN 322 | |
AVN-322 is a 5-HT6 receptor antagonist. 5-HT6R antagonists improves cognition in animal models of cognitive impairment. | |||
T126173 | Gypenoside VN3 | ||
Gypenoside VN3 is a useful organic compound for research related to life sciences. The catalog number is T126173 and the CAS number is 1235721-51-3. | |||
T24942 | VNRX-5133 | VNRX 5133 | |
VNRX-5133 is an injectable broad-spectrum β-lactamase inhibitor. VNRX-5133 is a novel β-lactamase inhibitor with potent and selective direct inhibitory activity against both serines- and Metallo-β-lactamases. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01861 | Vitronectin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exis... | |||
TMPY-00121 | Vitronectin Protein, Human, Recombinant (His) | Human | HEK293 |
Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exis... | |||
TMPJ-00472 | Vitronectin Protein, Human, Recombinant (Truncated, His) | Human | Human Cells |
Vitronectin, also known as VTN, is a large glycoprotein found in blood and the extracellular matrix (ECM). Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood ... | |||
TMPY-01403 | VNN1 Protein, Human, Recombinant (His) | Human | HEK293 |
Pantetheinase, also known as Pantetheine hydrolase, Vascular non-inflammatory molecule 1, Vanin-1, and VNN1, is a cell membrane protein which belongs to the CN hydrolase family and BTD/VNN subfamily. Vanin-1 contains one... | |||
TMPY-02529 | VNN1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Pantetheinase, also known as Pantetheine hydrolase, Vascular non-inflammatory molecule 1, Vanin-1, and VNN1, is a cell membrane protein which belongs to the CN hydrolase family and BTD/VNN subfamily. Vanin-1 contains one... | |||
TMPY-01614 | VNN2 Protein, Human, Recombinant (His) | Human | HEK293 |
Vascular non-inflammatory molecule 2, also known as glycosyl-phosphatidyl inositol-anchored protein GPI-8, Vanin-2, Protein FOAP-4 and VNN2, is a cell membrane protein that belongs to the CN hydrolase family and Vanin su... | |||
TMPY-05937 | Influenza A H1N1 (A/Sw/Bulnes/VN1401-P6SP/2018) Neuraminidase/NA Protein (His) | H1N1 | HEK293 |
Neuraminidases are enzymes that cleave sialic acid groups from glycoproteins. Influenza neuraminidase is a type of neuraminidase found on the surface of influenza viruses that enables the virus to be released from the ho... | |||
TMPY-02730 | VNN1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Pantetheinase, also known as Pantetheine hydrolase, Vascular non-inflammatory molecule 1, Vanin-1, and VNN1, is a cell membrane protein which belongs to the CN hydrolase family and BTD/VNN subfamily. Vanin-1 contains one... |