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Search Results for " t-25 "

Targets

32

Compounds

3

Natural Products

11

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T64387 2-Nitrobenzoic acid o-Nitrobenzoic acid Others
2-Nitrobenzoic acid (o-Nitrobenzoic acid) is a antiproliferation agent. 2-Nitrobenzoic acid shows IC50 of 8.3 μM to jurkat cell line expressing T type calcium channel alpha 1H or its splice variant delta 25.
T73463 NX-2127 NX2127,NX 2127 BTK
NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferative activity and inhibits the proliferation of BTKC481S mutant TMD8 ...
T6410 Bexarotene Ro 26-4455,Targretin,LGD1069 Retinoid Receptor , Autophagy
Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).
T8867 RO2959 Hydrochloride RO2959 HCl IL Receptor , Calcium Channel , Interleukin
RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
T5114 Pyridaben Calcium Channel , Parasite
Pyridaben is a METI acaricide that inhibits mitochondrial electron transport at complex I (METI; Ki = 0.36 nmol/mg protein in rat brain mitochondria).
TP1727 Gp100 (25-33), human
Gp100 (25-33), human is the amino acids 25-33 fragment of the human melanoma antigen. It is a 9-amino acid (AA) epitope restricted by H-2Db and recognized by the T cells.This is amino acids 25 to 33 fragment of human mel...
TP1416 Gp100 (25-33), human TFA (212370-40-6 free base) Gp100 (25-33), human TFA
Gp100 (25-33), human TFA is a 25-33 amino acid fragment of human melanoma antigen.Gp100 (25-33), human TFA is a 9-amino acid (AA) epitopes restricted by h-2db and recognized by T cells.
T63329 PD-1/PD-L1-IN-25
PD-1/PD-L1-IN-25 is an inhibitor of PD-1/PD-L1 interaction (IC50: 16.17 nM) that effectively activates anti-tumor immunity of T cells in PBMCs. PD-1/PD-L1-IN-25 can be used to study cancer.
T82179 HOXB7 8–25 MDM2 32-46
HOXB7 8–25 (MDM2 32-46) is a peptide epitope derived from MDM2 that can induce both antigen-specific and tumor-reactive CD4+ T cell responses [1].
T82485 ELAAWCRWGFLLALLPPGIAG
ELAAWCRWGFLLALLPPGIAG (P5), a 21-amino acid peptide (aa 5-25) derivative of the rat HER2/neu protein, has been shown to elicit cytotoxic T lymphocyte (CTL) responses in mice with HER2-positive tumors [1].
T82484 ELAAWCRWGFLLALLPPGIAG TFA
ELAAWCRWGFLLALLPPGIAG TFA (P5), a 21-amino-acid peptide (aa 5-25) originating from the rat HER2/neu protein, has been shown to elicit cytotoxic T lymphocyte (CTL) responses in mice with HER2-positive tumors [1].
T37370 Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red an...
T37553 (-)-Mycousnine
(-)-Mycousnine is a microbial metabolite and derivative of usnic acid originally isolated fromM. nawaethat has antibacterial and antifungal activities.1,2It is active against the Gram-positive bacteriaB. subtilis,K. rhiz...
T81308 RDN2150
RDN2150 (Compound 25), a ZAP-70 inhibitor with an IC50 of 14.6 nM, covalently binds to the C346 residue of ZAP-70, suppressing the expression of CD25 and CD69 and inhibiting the activation of CD4+ T cells, making it suit...
T83846 HOXB7 (8-25) TFA Homeobox B7 (8-25)
HOXB7 (8-25), a peptide fragment derived from homeobox B7 (HOXB7)—a key controller of cell growth and oncogene activator—facilitates antigen presentation when pulsed onto dendritic cells obtained from human peripheral bl...
T80411 Bactenecin 5
Bactenecin 5, a bovine antibacterial peptide, exhibits activity against Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae, with minimum inhibitory concentration (MIC) values ranging from 12-25 μg/mL [1]...
T79822 DGKα-IN-3
DGKα-IN-3 (example 25), with an IC50 of 283 nM, is a selective DGKα inhibitor that augments anti-PD-1's anti-tumor activity by promoting T cell proliferation and function, showing promise for cancer and immunology resear...
T37723 IT-143A
IT-143A is a bacterial metabolite originally isolated fromStreptomycessp. IT-143.1It is active against the bacteriumM. luteus(MIC = 6.25 μg/ml) and the fungiA. fumigatusandT. rubrumin vitro(MICs = 12.5-25 μg/ml). 1.Uraka...
T37536 Carbazomycin A
Carbazomycin A is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities.1,2It is active againstS. aureus,T. asteroides, andT. mentagrophytes(MIC = 12.5 μg/ml for all), as well a...
T83852 EGFRvIII Peptide TFA PEGFRvIII (9-mer),Epidermal Growth Factor Receptor Variant III Peptide
EGFRvIII peptide, a synthetic peptide mirroring the EGFRvIII fusion junction—a tumor-specific, perpetually active EGFR variant missing amino acids 6-273 of the wild-type—binds to HLA-A*0201-positive T2 cells under MHC cl...
T37537 Carbazomycin D
Carbazomycin D is a bacterial metabolite that has been found inStreptomycesand has diverse biological activities.1,2It is active against the fungiT. asteroidesandT. mentagrophytes(MIC = 100 μg/ml for both) and the bacter...
T36779 NG 25 (hydrochloride hydrate)
NG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1 (IC50s = 21.7 and 149 nM, respectively).1It also inhibits the Src family kinases Src and LYN (IC50s = 113 and 12.9 nM, respectively) and Abl family kinase...
T37594 Pericosine A
Pericosine A is a fungal metabolite that has been found inP. byssoidesand has anticancer activity.1It inhibits the growth of a variety of cancer cells, including breast, colon, lung, ovary, stomach, and prostate cell lin...
T35789 Palmitic acid-1-13C
Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plas...
T35517 4-deoxy Nivalenol-13C15 4-deoxy Nivalenol-13C15
4-deoxy Nivalenol-13C15is intended for use as an internal standard for the quantification of 4-deoxy nivalenol by GC- or LC-MS. 4-deoxy Nivalenol is a trichothecene mycotoxin that has been found inFusarium.1It binds to e...
T35680 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide
2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is an antimicrobial agent.1It is active against the Gram-negative bacteriaE. coli,P. aeruginosa, andS. marcescens(MICs = 64, 100, and 70 μg/ml, respectively), the Gr...
T35791 Palmitic acid-13C
Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid i...
T35775 HT-2 Toxin-13C22 HT-2 Toxin-13C22
HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene...
T35428 β-Rubromycin
β-Rubromycin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities.1 It inhibits the growth of HMO2, KATO-III, and MCF-7 cells with GI50 values of 0.5, 0.84, and <0.1 μM, ...
T35814 Urocortin III (human) (trifluoroacetate salt)
Urocortin III is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin II , frog sauvagine, and piscine urotensin I.1 Human urocortin II...
T35504 (±)10-HDHA
(±)10-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.[1][2] It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.[3][4][5] (±)10-HDHA is a potential marker of...
T36400 Para-amino-Blebbistatin
para-amino-Blebbistatin is a more water-soluble form of (S)-4'-nitro-blebbistatin , which is a more stable and less phototoxic form of (-)-blebbistatin .1,2,3 (-)-Blebbistatin is a selective cell-permeable inhibitor of n...

Compounds

2-Nitrobenzoic acid
T64387
Synonym: o-Nitrobenzoic acid
Target: Others
NX-2127
T73463
Synonym: NX2127,NX 2127
Target: BTK
Bexarotene
T6410
Synonym: Ro 26-4455,Targretin,LGD1069
Target: Retinoid Receptor, Autophagy
RO2959 Hydrochloride
T8867
Synonym: RO2959 HCl
Target: IL Receptor, Calcium Channel, Interleukin
Pyridaben
T5114
Synonym:
Target: Calcium Channel, Parasite
Gp100 (25-33), human
TP1727
Synonym:
Target:
Gp100 (25-33), human TFA (212370-40-6 free base)
TP1416
Synonym: Gp100 (25-33), human TFA
Target:
PD-1/PD-L1-IN-25
T63329
Synonym:
Target:
HOXB7 8–25
T82179
Synonym: MDM2 32-46
Target:
ELAAWCRWGFLLALLPPGIAG
T82485
Synonym:
Target:
ELAAWCRWGFLLALLPPGIAG TFA
T82484
Synonym:
Target:
Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
T37370
Synonym:
Target:
(-)-Mycousnine
T37553
Synonym:
Target:
RDN2150
T81308
Synonym:
Target:
HOXB7 (8-25) TFA
T83846
Synonym: Homeobox B7 (8-25)
Target:
Bactenecin 5
T80411
Synonym:
Target:
DGKα-IN-3
T79822
Synonym:
Target:
IT-143A
T37723
Synonym:
Target:
Carbazomycin A
T37536
Synonym:
Target:
EGFRvIII Peptide TFA
T83852
Synonym: PEGFRvIII (9-mer),Epidermal Growth Factor Receptor Variant III Peptide
Target:
Carbazomycin D
T37537
Synonym:
Target:
NG 25 (hydrochloride hydrate)
T36779
Synonym:
Target:
Pericosine A
T37594
Synonym:
Target:
Palmitic acid-1-13C
T35789
Synonym:
Target:
4-deoxy Nivalenol-13C15
T35517
Synonym: 4-deoxy Nivalenol-13C15
Target:
2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide
T35680
Synonym:
Target:
Palmitic acid-13C
T35791
Synonym:
Target:
HT-2 Toxin-13C22
T35775
Synonym: HT-2 Toxin-13C22
Target:
β-Rubromycin
T35428
Synonym:
Target:
Urocortin III (human) (trifluoroacetate salt)
T35814
Synonym:
Target:
(±)10-HDHA
T35504
Synonym:
Target:
para-amino-Blebbistatin
T36400
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T3794 Pentagalloylglucose Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose Influenza Virus
1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses poten...
T14063 7α,25-Dihydroxycholesterol 7α,25-OHC EBI2/GPR183 , Endogenous Metabolite
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cel...
T36438 Sporogen-AO 1
Sporogen-AO 1 is a fungal metabolite originally isolated fromA. oryzaethat has diverse biological activities.1,2,3,4,5It inhibits HIV-1 Tat transactivation in a cell-based assay with an IC50value of 15.8 μM.4Sporogen-AO ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01473 Thy1/CD90 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Thy1/CD90 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.2 kDa and the accession number is P01831.
TMPY-02245 SNAP-25 Protein, Human, Recombinant (His) Human E. coli
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains...
TMPJ-00140 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated Cynomolgus HEK293 Cells
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats...
TMPK-01141 TIM-4/TIMD4 Protein, Human, Recombinant (aa 25-314, His) Human HEK293 Cells
Tim4 is a transmembrane protein as the phosphatidylserine (PS) receptor, known as T cell immunoglobulin and mucin domain containing protein-4. It is expressed highly in macrophages, and macrophage Tim-4 inhibits inflamma...
TMPK-00059 CD94 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
CD94 is an approximately 25 kDa type 2 transmembrane protein that plays an important role in regulating natural killer (NK) cell activation.CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecul...
TMPK-00058 CD94 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
CD94 is an approximately 25 kDa type 2 transmembrane protein that plays an important role in regulating natural killer (NK) cell activation.CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecul...
TMPK-00688 PD-1 Protein, Canine, Recombinant (aa 25-170, hFc) Canine HEK293 Cells
Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the ...
TMPK-00180 PD-1 Protein, Human, Recombinant (aa 25-167, hFc & Avi), Biotinylated Human HEK293 Cells
Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the ...
TMPJ-00353 ILDR2 Protein, Human, Recombinant (His) Human HEK293 Cells
ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasis. The human ILDR2 lumenal domain shares a 99% and 98% homo...
TMPH-00895 Human adenovirus B serotype 3 Hexon protein (His & Myc) HAdV-3 E. coli
Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. ...
TMPY-02440 SAP/SH2D1A Protein, Human, Recombinant (His) Human E. coli
SH2domain-containing protein 1A (SH2D1A / SAP) is a 128 amino acid protein, containing a single Src homology 2 (SH2) domain, flanked by 5 amino acids at the N-terminus and 25 amino acids at the C-terminus. The absence of...
TargetMol