silybin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T75437	Silybin
	Silybin, a flavonolignan extracted from milk thistle (Silybum marianum) seeds, effectively induces apoptosis and demonstrates hepatoprotective, antioxidant, anti-inflammatory, and anti-cancer activities [1] [2].
TN2211	Silybin B	Silibinin B	Apoptosis , Beta Amyloid , Bcr-Abl
	Silybin B (Silibinin B) is an effective inhibitor of raloxifene 4 '- and 6-glucosalylation, an effective anti-fibrinogenic and anti-oligomeric component of Silymarin, with free radical scavenging activity of 1, 1-dipheny...		Apoptosis , Beta Amyloid , Bcr-Abl
T6670	Silymarin	Silybin B	SARS-CoV
	Silymarin (Silybin B) (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases.		SARS-CoV
T1660	Silibinin	Silibinin A,Silybin,Silymarin I	Reactive Oxygen Species , Autophagy
	Silibinin (Silybin) is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin an...		Reactive Oxygen Species , Autophagy
T3797	Isosilybin	Isosilybinin,Isosilibinin,Silymarin,Silybin B,Q-100795	P450
	Isosilybin (Isosilibinin) and Silybin might be suitable candidates to design potent PXR antagonists to prevent drug-drug interactions via CYP3A4 in cancer patients.		P450
TN1805	Isosilybin B		Apoptosis , Androgen Receptor
	Isosilybin B is a flavonolignan extracted from silymarin that exhibits anti-prostate cancer (PCA) activity, inhibits cancer cell proliferation, and contributes to G1-phase blockade and apoptosis.Isosilybin B induces degr...		Apoptosis , Androgen Receptor
TN1804	Isosilybin A		Apoptosis , Tyrosinase , PPAR , ABC
	Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC50=12.1-44.9μM) of tyrosinase. Isosilybin A shows anti-angio...		Apoptosis , Tyrosinase , PPAR , ABC
T125202	2,3-Dehydrosilybin A
	2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.
T125883	2,3-Dehydrosilybin B
	2,3-Dehydrosilybin B is a useful organic compound for research related to life sciences and the catalog number is T125883.
TN5154	Torilolone		Others
	Torilin and torilolone show hepatoprotective effects on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells,the EC50 values are 20.6 +/- 1.86 and 3.6 +/- 0.1 microM, respectively; and silybin as a positive c...		Others
T15886	M-PEG4-Tos		Others
	m-PEG4-Tos, a PEG-based PROTAC linker derived from silybin ethers, finds application in the synthesis of Silymarin[1].		Others
T15939	M-PEG8-Tos		Others
	Tos-PEG8-m, a PEG-based PROTAC linker, is a derivative of silybin ethers. It is utilized in the synthesis of Silymarin[1].		Others
T15903	M-PEG5-Tos		Others
	m-PEG5-Tos is a PEG-based PROTAC linker derived from silybin ethers. This compound serves as an essential component in the synthesis of Silymarin[1].		Others