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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7799 | BMP signaling agonist sb4 | SB 4 | TGF-beta/Smad |
BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM) | |||
T1726 | SB-431542 | SB 431542 | ALK , TGF-beta/Smad |
SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiatio... | |||
T23321 | SB 328437 | (S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate,ZINC29222893 | CCR |
SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM). | |||
T6658 | SB-408124 | OX Receptor | |
SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor. | |||
T6659 | SB 415286 | SB415286 | Apoptosis , GSK-3 |
SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β. | |||
T2278 | Piboserod | SB-207266 | 5-HT Receptor |
Piboserod (SB-207266) (SB 207266) is a selective 5-HT(4) receptor antagonist. | |||
T1764 | Adezmapimod | PB 203580,RWJ 64809,SB203580 | Mitophagy , p38 MAPK , Autophagy |
Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive. Adezmapimod possesses autophagy and mitochondrial autophagy activating activity. Adezmapimod displays more than 100... | |||
T38602 | (E/Z)-Eltrombopag 13C4 | (E/Z)-Eltrombopag 13C4,(E/Z)-SB-497115 13C4 | |
(E/Z)-Eltrombopag 13C4 ((E/Z)-SB-497115 13C4) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead... | |||
T6644 | Rolipram | SB 95952,ZK 62711,(R,S)-Rolipram | HIV Protease , Antibacterial , PDE |
Rolipram (SB 95952) is a phosphodiesterase 4 inhibitor with antidepressant properties. | |||
T77426 | Pascolizumab | SB-240683 | IL Receptor |
Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis. | |||
T6445 | Cilomilast | SB-207499,Ariflo | PDE |
Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3. | |||
T4674 | SB297006 | SB 297006 | CCR |
SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ... | |||
T124135 | Antibiotic SB 202742 | ||
Antibiotic SB 202742 is a useful organic compound for research related to life sciences. The catalog number is T124135 and the CAS number is 83173-24-4. | |||
T36376 | SB-612111 | ||
SB-612111 is a novel and potent human opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). SB-612111 exhibits selectivity for μ-, κ- and δ-receptors with Ki values of 57.6... |