ptp — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7541	PTP inhibitor 1	PTP Inhibitor II	Phosphatase
	PTP inhibitor 1 is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)),with Ki of128 μM.		Phosphatase
T22137	PTP Inhibitor IV		Others
	PTP Inhibitor IV is an effective protein tyrosine phosphatase (PTP) inhibitor, which can selectively inhibit DUSP14 phosphatase activity (IC50.5.21μm). PTP Inhibitor IV inhibited SHP-2, PTP1B, PTp-ε, PTP Meg-2, PTP-σ, PT...		Others
T10927	Cyt-PTPε Inhibitor-1	Cyt-PTP\|A Inhibitor-1	Phosphatase , Src
	Cyt-PTPε Inhibitor-1 (A Inhibitor-1) is an inhibitor of cytosolic protein tyrosine phosphatase ε. Cyt-PTPε Inhibitor-1 blocks the dephosphorylation of c-Src and exhibits anti-osteoclastic activity.		Phosphatase , Src
T6667	SF1670	PTP CD45 Inhibitor,PTPase CD45 Inhibitor	Phosphatase , PTEN , Autophagy
	SF1670 (PTPase CD45 Inhibitor) is a specific PTEN inhibitor with IC50 of 2 μM.		Phosphatase , PTEN , Autophagy
T80870	VE-PTP-IN-1
	VE-PTP-IN-1 (compound 2) is a selective inhibitor of the vascular endothelial protein tyrosine phosphatase (VE-PTP), possessing weakly acidic properties. It is associated with the regulation of vascular homeostasis and a...
T7084	2-Bromo-4'-hydroxyacetophenone	SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide	Phosphatase
	2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SH...		Phosphatase
T15243	Ertiprotafib	PTP 112	Phosphatase , PPAR
	Ertiprotafib is a PTP1B, IkB kinase β (IKK-β), and a dual PPARα and PPARβ agonist inhibitor ( IC50s: 1.6 μM for PTP1B, 400 nM for IKK-β, an EC50 of ~1 μM for PPARα/PPARβ).		Phosphatase , PPAR
T39856	Purine riboside triphosphate	PTP,Purine riboside triphosphate
	Purine riboside triphosphate, a derivative of purine riboside, exhibits structural similarity to adenosine. This naturally occurring base analog possesses inhibitory effects on carcinogenic growth, particularly in cancer...
T12577	PTP1B-IN-3		Phosphatase
	PTP1B-IN-3 is a selective and potent PTP1B inhibitor with anticancer activity that inhibits PTP1B and TCPTP.PTP1B-IN-3 is used in the study of diabetes.		Phosphatase
T4256	PTP1B-IN-2		Phosphatase
	PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM).		Phosphatase
T4340	SPI-112		Phosphatase
	SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinetics to Shp2.		Phosphatase
T7356	PTP1B-IN-1	PTP1B inhibitor	Phosphatase
	PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)		Phosphatase
T40745	PTP1B-IN-13	PTP1B-IN-13
	PTP1B-IN-13, a potent and selective inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B), effectively targets the allosteric site, exhibiting an IC50 value of 1.59 μM.
T40835	PTP1B-IN-14	PTP1B-IN-14
	PTP1B-IN-14 is a selective inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) that targets the allosteric site, exhibiting an inhibitory concentration (IC50) value of 0.72 μM.
T22276	Bis(maltolato)oxovanadium(IV)	BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV)	Phosphatase , Others
	Bis(maltolato)oxovanadium(IV) (BMOV) is a potent, reversible, competitive and orally active pan-PTP (protein tyrosine phosphatases)inhibitor with insulin-mimicking effects and anti-diabetic properties. BMOV is a potent i...		Phosphatase , Others
T24073	PTP1B-IN-4	NUN 17724,PTP1B-inhibitor-2,PTP1B IN 2,PTP1B-IN-2,PTP1B-inhibitor-4,FRJ,PTP1B inhibitor 4,NUN17724,PTP1B inhibitor 2,PTP1BIN2,NUN-17724	Phosphatase
	PTP1B-IN-4 (NUN-17724) is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes.		Phosphatase
T4491	LMPTP INHIBITOR 1 hydrochloride	LMPTP INHIBITOR 1 hydrochloride (1908414-82-3(free base))	Phosphatase
	LMPTP INHIBITOR 1 hydrochloride is a selective inhibitor of low molecular weight protein tyrosine phosphatase ( LMPTP ), with an IC 50 of 0.8 μM for LMPTP-A.		Phosphatase
T41298	LMPTP INHIBITOR 1 dihydrochloride		Phosphatase
	LMPTP Inhibitor 1 Dihydrochloride is a compound selectively targeting low molecular weight protein tyrosine phosphatase (LMPTP), exhibiting potent inhibitory activity with an IC50 value of 0.8 μM for LMPTP-A.		Phosphatase
T4081	MPTP hydrochloride	MPTP-hydrochloride	Apoptosis , Dopamine Receptor
	MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability. MPTP hydrochloride is toxic to dopaminergic neurons, which can lead to Parkinson's disease, and is widely used in th...		Apoptosis , Dopamine Receptor
T67893	PTP1B-IN-22		Phosphatase
	PTP1B-IN-22 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that inhibits glucose uptake in skeletal muscle L6 myotubes.		Phosphatase