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Search Result

Search Results for " pci "

Targets

Apoptosis HDAC

29

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6325 PCI-34051 PCI 34051 Apoptosis , HDAC
PCI-34051 is an effective and selective HDAC8 inhibitor (IC50: 10 nM).
T4337 PCI 29732 PCI29732,PCI-29732 Others , BCRP , BTK
PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.
T3469 PCI-27483 PCI27483 Others
PCI-27483 is an activated coagulation factor VIIa inhibitor with antithrombotic effects in a baboon model of arterial thrombosis. It also inhibits the growth of BxPC3 xenografts by 42% and 85% at doses of 60 and 90 mg/kg...
T1835 Ibrutinib PCI-32765 Tyrosine Kinases , Src , BTK , Ligands for Target Protein for PROTAC
Ibrutinib (PCI-32765) is an irreversible inhibitor of BTK (IC50: 0.5 nM) that selectively blocks B cell activation.
T0431 Abexinostat CRA 24781,PCI24781,PCI-24781,PCI 24781,CRA 024781 HDAC
PCI-24781 (Abexinostat (PCI24781)) is a new pan-HDAC inhibitor mainly targeting HDAC1 (Ki: 7 nM), also have moderate inhibitory for HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2.
T16441 PCI-33380 BTK
PCI-33380 is an irreversible inhibitor of Bruton's Tyrosine Kinase.
T10883 CRA-026440 PCI-34051 HDAC
CRA-026440(PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7 and 20 nM, respectively. CRA-026440 has anti-tumor and anti-a...
T33487 Motexafin gadolinium PCI0120,Gd texaphyrin,PCI-0120,PCI 0120,Gd-Texgadolinium,API-GP 3
Motexafin gadolinium, also known as PCI 0120, is a synthetic metallotexaphyrin with radiosensitizing and chemosensitizing properties. Motexafin gadolinium accumulates in tumor cells preferentially due to their increased ...
T16440 Ibrutinib Racemate PCI-32765 (Racemate) Others
Ibrutinib is a selective, irreversible Btk inhibitor (IC50: 0.5 nM). Ibrutinib Racemate is the racemate of Ibrutinib.
T11601 Ibrutinib-d5 PCI-32765 D5,Ibrutinib D5 Others
Ibrutinib D5 is a deuterium-labeled Ibrutinib. Ibrutinib is an irreversible Btk inhibitor.
T36429 Dihydrodiol-Ibrutinib
PCI 45227 is an active metabolite of the Bruton's tyrosine kinase inhibitor ibrutinib .1PCI 45227 is formed from ibrutinib by the cytochrome P450 (CYP) isoform CYP3A. 1.Veeraraghavan, S., Viswanadha, S., Thappali, S., et...
T8561 Apcin APC
Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substr...
T61144 Hepcidin antagonist-1 Others
Hepcidin antagonist-1 is an iron-modulating antagonist.Hepcidin antagonist-1 can be used to study metabolic disorders such as iron-deficiency diseases and anemia.
T64339 Apcin A HCL APC
Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to...
T76828 Sonepcizumab LT 1009 LPL Receptor
Sonepcizumab (LT 1009) is a fully humanized monoclonal antibody against S1P. Sonepcizumab has anti-cancer activity and can be used to study metastatic renal cell carcinoma (mRCC) to prevent eye scarring after glaucoma fi...
T76271 Hepcidin-25 (human)
Hepcidin-25 (human), an iron metabolism modulator, exhibits both anti-inflammatory and antibacterial activity through the modulation of iron-mediated oxidant injury [1].
T80108 Hepcidin-1 (mouse)
Hepcidin-1 (mouse) is a peptide hormone that regulates iron balance, elevates mRNA for TRAP, cathepsin K, and MMP-9, and promotes TRAP-5b protein secretion. This compound also reduces FPN1 protein levels and boosts intra...
T76585 Hepcidin-20 (human)
Hepcidin-20 (human), a peptide characterized by its histidine content, cysteine-rich composition, and β-sheet structure, exhibits antifungal properties. Furthermore, it effectively inhibits biofilm formation and disrupts...
T25298 Dealanylalahopcin
Dealanylalahopcin is a procollagen prolyl-4-hydroxylase inhibitor.
T78037 Hepcidin-1 (mouse) TFA
Hepcidin-1 (mouse) TFA, an endogenous peptide hormone, regulates iron homeostasis by upregulating mRNA levels of TRAP, cathepsin K, and MMP-9, enhancing TRAP-5b protein secretion, and downregulating FPN1 protein levels, ...
T80413 Bass hepcidin
Bass hepcidin exhibits antimicrobial activity against Escherichia coli [1].
T80082 Hepcidin-25 (human) (acetate) Endogenous Metabolite
Hepcidin-25 (human) acetate is a modulator of iron metabolism that demonstrates anti-inflammatory and antibacterial effects through the modulation of iron-mediated oxidant injury [1].
T25022 Alahopcin Nourseimycin,Antibiotic B 52653,B-52653,Antibiotic T 804A
Alahopcin is a new dipeptide antibiotic generated by Streptomyces albulus subsp. ochragerus subsp. nov.
T24495 MPCI
MPCI is a selective melanocortin-4 receptor antagonist.
T80341 Seabream hepcidin
Seabream hepcidin, an antimicrobial peptide, exhibits antibacterial (V. anguillarum), antifungal (S. cerevisiae), and antiviral activities against hemorrhagic septicemia virus [1].
T10345 Apcin-A Others
Apcin-A is an anaphase-promoting complex (APC) inhibitor. It interacts strongly with Cdc20 and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be used to synthesize the PROTAC CP5V.
T82888 Bibapcitide
Bibapcitide, a 26-amino-acid peptide, acts as a thrombosis inhibitor [1].
T22323 Enoxaparin sodium Thrombin
Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment myocardial infarction (STEMI), or STEMI with subsequent percu...
T31793 Fimaporfin TPCS2a,Disulfonated tetraphenyl chlorin
Fimaporfin, also known as TPCS2a, is a potent chlorin-based photosensitizer, Fimaporfin is consisted of a mixture of three isomers A, B and C (25%,50%,25%). Fimaporfin has been developed by di-imide reduction of disulfon...

Compounds

PCI-34051
T6325
Synonym: PCI 34051
Target: Apoptosis, HDAC
PCI 29732
T4337
Synonym: PCI29732,PCI-29732
Target: Others, BCRP, BTK
PCI-27483
T3469
Synonym: PCI27483
Target: Others
Ibrutinib
T1835
Synonym: PCI-32765
Target: Tyrosine Kinases, Src, BTK, Ligands for Target Protein for PROTAC
Abexinostat
T0431
Synonym: CRA 24781,PCI24781,PCI-24781,PCI 24781,CRA 024781
Target: HDAC
PCI-33380
T16441
Synonym:
Target: BTK
CRA-026440
T10883
Synonym: PCI-34051
Target: HDAC
Motexafin gadolinium
T33487
Synonym: PCI0120,Gd texaphyrin,PCI-0120,PCI 0120,Gd-Texgadolinium,API-GP 3
Target:
Ibrutinib Racemate
T16440
Synonym: PCI-32765 (Racemate)
Target: Others
Ibrutinib-d5
T11601
Synonym: PCI-32765 D5,Ibrutinib D5
Target: Others
Dihydrodiol-Ibrutinib
T36429
Synonym:
Target:
Apcin
T8561
Synonym:
Target: APC
Hepcidin antagonist-1
T61144
Synonym:
Target: Others
Apcin A HCL
T64339
Synonym:
Target: APC
Sonepcizumab
T76828
Synonym: LT 1009
Target: LPL Receptor
Hepcidin-25 (human)
T76271
Synonym:
Target:
Hepcidin-1 (mouse)
T80108
Synonym:
Target:
Hepcidin-20 (human)
T76585
Synonym:
Target:
Dealanylalahopcin
T25298
Synonym:
Target:
Hepcidin-1 (mouse) TFA
T78037
Synonym:
Target:
Bass hepcidin
T80413
Synonym:
Target:
Hepcidin-25 (human) (acetate)
T80082
Synonym:
Target: Endogenous Metabolite
Alahopcin
T25022
Synonym: Nourseimycin,Antibiotic B 52653,B-52653,Antibiotic T 804A
Target:
MPCI
T24495
Synonym:
Target:
Seabream hepcidin
T80341
Synonym:
Target:
Apcin-A
T10345
Synonym:
Target: Others
Bibapcitide
T82888
Synonym:
Target:
Enoxaparin sodium
T22323
Synonym:
Target: Thrombin
Fimaporfin
T31793
Synonym: TPCS2a,Disulfonated tetraphenyl chlorin
Target:

Recombinant Proteins

Species：
Human (1)
Larimichthys crocea (1)
Mouse (1)
Expression System：
E. coli (2)
HEK293 Cells (1)
Tag：
C-6xHis (1)
N-GST (1)
Tag Free (1)
Cat No. Product Name Species Expression System
TMPJ-00490 Serpin A5 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent i...
TMPH-02389 Hepcidin Protein, Larimichthys crocea, Recombinant Larimichthys crocea E. coli
Hepcidin Protein, Larimichthys crocea, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 2.5 kDa and the accession number is A1Z0M0.
TMPK-01170 Hepcidin/HAMP Protein, Mouse, Recombinant (GST) Mouse E. coli
Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of ge...
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