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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19486 | Nucleoside-Analog-2 | Others | |
Nucleoside-Analog-2 is a 4'-Azidocytidine analogue, used to against Hepatitis C virus (HCV) replication. | |||
T9727 | 2'-Fluoro-2'-Deoxyadenosine | Nucleoside Antimetabolite/Analog | |
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors ex... | |||
T9726 | 2’-OMe-Guanosine | Apoptosis , Nucleoside Antimetabolite/Analog | |
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect. | |||
T38238 | 2'-Deoxy-2'-fluorocytidine | Nucleoside Antimetabolite/Analog , Influenza Virus | |
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency o... | |||
T7514 | N2-Methylguanosine | Nucleoside Antimetabolite/Analog , Endogenous Metabolite | |
N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA's | |||
T38236 | 2′-Deoxy-2′-fluoroguanosine | Nucleoside Antimetabolite/Analog , Influenza Virus | |
2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respirator... | |||
T19382 | Isoguanine | Nucleoside Antimetabolite/Analog | |
Isoguanine is a purine base that is an isomer of guanine. A building block in organic synthesis. | |||
T38958 | DMT-2′Fluoro-dU Phosphoramidite | 2'-F-dU Phosphoramidite | Nucleoside Antimetabolite/Analog |
DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides. | |||
T10066 | 2',5'-Dideoxyadenosine | Adenylyl cyclase , Adrenergic Receptor , AChR | |
2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site (IC50: 3 μM). | |||
T12399 | Peldesine | BCX 34 | Nucleoside Antimetabolite/Analog , HIV Protease |
Peldesine (BCX 34) is an effective, competitive, reversible, and orally active inhibitor of purine nucleoside phosphorylase. Peldesine inhibits T-cell proliferation with an IC50 of 800 nM. Peldesine can be used in resear... | |||
T7518 | Deoxycytidine triphosphate trisodium salt | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Antibiotic |
Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria. | |||
T40192 | DGTP | 2'-Deoxyguanosine-5'-triphosphate | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP. | |||
T6603 | Nelarabine | GW 506U78,Nelzarabine,506U78 | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells. | |||
T1508 | Decitabine | Dacogen,NSC 127716,Deoxycytidine,5-Aza-2'-deoxycytidine | Apoptosis , Nucleoside Antimetabolite/Analog , DNA Methyltransferase |
Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis... | |||
T6794 | 5-BrdU | BUdR,Broxuridine,5-bromo-2'-deoxyuridine,Bromodeoxyuridine,BRDU | Nucleoside Antimetabolite/Analog , Others |
5-BrdU (Broxuridine) , a nucleoside analog, are used in the detection of proliferating cells and competes with thymidine for incorporation into DNA. | |||
T0688 | Ganciclovir | BW 759,RS-21592,2'-Nor-2'-deoxyguanosine | Nucleoside Antimetabolite/Analog , Others , Antibiotic , Antifection , HSV |
Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegaloviru... | |||
T0964 | Floxuridine | 5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640 | Apoptosis , Nucleoside Antimetabolite/Analog , Others , DNA/RNA Synthesis , Antibacterial , HSV |
Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity. | |||
T22337 | Ganciclovir sodium | RS-21592 sodium,Cytovene IV sodium,2'-Nor-2'-deoxyguanosine sodium,BW 759 sodium | Nucleoside Antimetabolite/Analog , Others , Antifection , HSV |
Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1). | |||
TNU0159 | FMAU | 2'-Deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine | Apoptosis |
FMAU (2'-Deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine) is a thymine nucleoside analog with insertional activity on replicating DNA.FMAU can be used to label cells and track DNA synthesis. | |||
T16325 | NITD008 | 7-Deaza-2'-C-acetylene-adenosine | Others |
NITD008 (7-Deaza-2'-C-acetylene-adenosine) is a potent and selective adenosine nucleoside inhibitor.NITD008 is an adenosine nucleoside analog with broad-spectrum antiviral activity that inhibits dengue, animal cupripoxvi... |