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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5283 | NADH disodium salt | Disodium NADH,NADH, disodium salt hydrate | Others , Endogenous Metabolite |
NADH disodium salt (Disodium NADH) hydrate is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process, NADH disodium salt hydrate becomes oxid... | |||
T8347 | Rifamycin S | Reactive Oxygen Species , ROS , Antibacterial , Antibiotic | |
Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteria | |||
T36420 | IM-156 acetate | HL271 acetate | |
IM-156 acetate, an activator of NADH dehydrogenase (IC50=2.2 μM) and AMP-activated protein kinase alpha (AMPKα), is an orally available and bioavailable inhibitor of mitochondrial oxidative phosphorylation (OxPhos).IM-15... | |||
TN1774 | Isobavachromene | Others , Antibacterial | |
Isobavachromene is an inhibitor of NADH-Ubiquinone oxidoreductase and ornithine decarboxylase. Isobavachromene has antifungal activity. | |||
T19343 | Sn-Glycerol 3-phosphate | Glycerol 3-phosphate,sn-Glycerol 3-phosphate lithium salt | Endogenous Metabolite |
sn-Glycerol 3-phosphate is produced by the reduction of dihydroxyacetone phosphate by NADH formed during glycolysis of the cytoplasmic glycerol 3-phosphate dehydrogenase pathway. | |||
T73486 | RIG012 | Others | |
RIG012 is a potent RIG-I inhibitor with an IC50 value of 0.71 μM measured by NADH-coupled ATPase.RIG012 inhibited the expression of IFN-β and ISG hRsad2. | |||
T7575L1 | [Sar1, Ile8]-Angiotensin II acetate | RAAS | |
[Sar1, Ile8]-Angiotensin II acetate activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells. [Sar1, Ile8]-Angiotensin II acetate has multiple effects on vascu... | |||
T20067 | WST-1 | WST 1 | |
WST-1 is a cytotoxic, water-soluble tetrazolium salt that induces intracellular mitochondrial dehydrogenases to undergo NADH-dependent enzymatic reactions, releasing water-soluble methylbenzene products.WST-1 can be used... | |||
T60774 | NITD-916 | NITD916,NITD 916 | Antibiotic |
NITD-916 is an orally active and highly lipophilic inhibitor of Mycobacterium enoyl reductase InhA with an IC50 of 570 nM.NITD-916 is a potent 4-hydroxy-2-pyridone derivative that forms a ternary complex with InhA and NA... | |||
T9558 | KL-11743 | transporter | |
KL-11743 specifically blocks glucose metabolism, triggering an acute collapse in NADH pools and a striking accumulation of aspartate, indicating a dramatic shift toward oxidative phosphorylation in the mitochondria. | |||
T22223 | 3PO | Glucokinase , Autophagy | |
3PO is a small-molecule inhibitor of PFKFB3 (IC50: 22.9 μM), inhibiting the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines (IC50: 1.4-24 μM). It suppresses glucose uptake, and decrea... | |||
T1609 | NAD+ | Cozymase,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD | NADPH , Endogenous Metabolite |
NAD+ (β-Nicotinamide Adenine Dinucleotide) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous... | |||
T19343L | Glycerol 3-phosphate biscyclohexylammonium salt | Endogenous Metabolite | |
Glycerol 3-phosphate biscyclohexylammonium salt is an endogenous metabolite produced by cytosolic glycerol 3-phosphate dehydrogenase pathway. | |||
T16342 | KL1333 | NQO1 activator 1 | NADPH , Mitochondrial Metabolism |
KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 ... | |||
T71866 | Cochlioquinone B | ||
Cochlioquinone B is a phytotoxin that inhibits NADH oxidase and NADH-2,3-dimethoxy-5-pentyl-1,4-benzoquinone reductase from heart mitochondria. | |||
T81570 | Paecilaminol | FKI-0550 | |
Paecilaminol (FKI-0550) is a potent inhibitor of the NADH-fumarate reductase enzyme, demonstrating an inhibitory concentration (IC50) of 5.1 µM against the NADH-fumarate reductase derived from Ascaris suum [1]. | |||
T70935 | Phenoxan | ||
Phenoxan is isolated from Polyangium; inhibits electron transport at NADH-ubiquinone oxidoreductase. | |||
T74201 | 3′-Hydroxy-4′-O-methylglabridin | ||
3′-Hydroxy-4′-O-methylglabridin effectively prevents NADH-dependent peroxidation, exhibiting potent antioxidant properties [1]. | |||
T36875 | Sartorypyrone D | ||
Sartorypyrone D is a fungal metabolite that has been found inN. fischeri.1It inhibits NADH fumarate reductase (NFRD; IC50= 1.7 μM inA. suummitochondria) and NADH oxidase (IC50= 3 μM in bovine heart mitochondria). Sartory... | |||
T75289 | NAD sodium | ||
NAD sodium (β-Nicotinamide Adenine Dinucleotide sodium) is an analogue of NAD that can be reduced to β-nicotinamide adenine dinucleotide (NADH) through reactions that oxidize organic substrates. Furthermore, NAD sodium c... |