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KL1333

Catalog No. T16342 CAS 1800405-30-4

Synonyms: NQO1 activator 1

KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 is an orally available NAD+ modulator. It reacts with NAD(P)H: NQO1 as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation.

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KL1333, CAS 1800405-30-4

Pack Size	Availability	Price/USD
1 mg	In stock	$ 140.00
2 mg	In stock	$ 197.00
5 mg	In stock	$ 288.00
10 mg	In stock	$ 449.00
25 mg	In stock	$ 739.00
50 mg	In stock	$ 987.00
100 mg	In stock	$ 1,390.00
1 mL * 10 mM (in DMSO)	In stock	$ 276.00

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Purity: 99.27%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	NQO1 activator 1
Molecular Weight	240.26
Formula	C14H12N2O2
CAS No.	1800405-30-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 245 mg/mL (1019.73 mM), Sonification is recommended.

References and Literature

1. Seo KS, et al. KL1333, a Novel NAD+ Modulator, Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts. Front Neurol. 2018 Jul 5;9:552.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Clinical Compound Library Orally Active Compound Library Bioactive Compounds Library Max Anti-Aging Compound Library Bioactive Compound Library Mitochondria-Targeted Compound Library Metabolism Compound Library Cuproptosis Compound Library

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Related compounds with same targets

AKR1C3-IN-1 Casein kinase 1δ-IN-9 Setanaxib Carvedilol phosphate hemihydrate Resveratrol HTS07545 NQO1 substrate S19-1035

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

KL1333 1800405-30-4 Metabolism Mitochondrial Metabolism NADPH Inhibitor KL-1333 inhibit KL 1333 NQO1 activator 1 inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.