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Search Result

Search Results for " ms-5 "

Targets

Others PROTAC Linker

43

Compounds

3

Natural Products

11

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T18588 Propargyl-PEG5-Ms Propargyl-PEG6-Ms Others , PROTAC Linker
Propargyl-PEG5-Ms (Propargyl-PEG6-Ms) is a PEG-based PROTAC linker. Propargyl-PEG5-Ms can be used in the synthesis of PROTACs.
T9146 ms48107 Benzenemethanol, 2-[4-amino-6-[[(4-phenoxyphenyl)methyl]amino]-1,3,5-triazin-2-yl]-3-fluoro- Others
MS48107 is a potent, selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68), demonstrating specificity for GPR68 over closely related proton GPCRs, neurotransmitter transporters, and hERG ion ch...
T14541 Benzyl-PEG5-Ms Others
Benzyl-PEG5-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi...
T15894 M-PEG5-Ms Others
m-PEG5-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
T17650 Boc-N-Amido-PEG5-Ms Others
Boc-N-Amido-PEG5-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syst...
T16150 Ms-PEG5-t-butyl ester Ms-PEG4-t-butyl ester Others
Ms-PEG5-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sy...
T6923 Ozanimod RPC-1063 S1P Receptor , LPL Receptor
Ozanimod (RPC-1063) (RPC1063) is a specific oral S1P Receptor 1 modulator. Ozanimod has been used in trials studying the treatment of Crohn's Disease, Ulcerative Colitis, Multiple Sclerosis, and Relapsing Multiple Sclero...
T23029 MS 245 oxalate Others
MS 245 oxalate is a 5-HT6 antagonist.
T62732 S1P1 agonist 5
S1P1 agonist 5 is a selective, orally active S1P1 agonist. S1P1 agonist 5 inhibits the drainage of lymphocytes from lymphoid tissue into peripheral blood. S1P1 agonist 5 has potential for studies in multiple sclerosis (M...
T36895 5-Fluorouracil-13C,15N2 5-Fluorouracil-13C,15N2
5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking...
T41156 MS 39
MS 39 is a highly effective, highly affinity and selective depressant of mutant epidermal growth factor receptor (EGFR) with high efficiency, high affinity and selectivity. MS 39, conjured by gefitinib to VHL ligand via ...
T38037 Caffeic Acid-13C3 Caffeic Acid-13C3
Caffeic acid-13C3 is an isotopically enriched form of caffeic acid that is intended for use as an internal standard for the quantification of caffeic acid by GC- or LC-MS. Caffeic acid is an inhibitor of 5-LO , with IC50...
T71211 Rizatriptan-d6 benzoate salt
Rizatriptan-d6 is intended for use as an internal standard for the quantification of rizatriptan by GC- or LC-MS. Rizatriptan is an agonist of the serotonin receptor subtypes 5-HT1B and 5-HT1D. It is selective for 5-H...
T36556 (±)5(6)-DiHET lactone
5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-δ-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS. 5,6-DiHET potently induces...
T71302 Norfluoxetine-d5 HCl
Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine b...
T71893 Clobetasol Propionate-d5
Clobetasol propionate-d5 is intended for use as an internal standard for the quantification of clobetasol propionate by GC- or LC-MS. Clobetasol propionate is a corticosteroid. It binds to glucocorticoid receptors in a c...
T35718 N-desmethyl Rosuvastatin (sodium salt hydrate)
N-desmethyl Rosuvastatin is an active metabolite of the HMG-CoA reductase inhibitor rosuvastatin .1,2N-desmethyl Rosuvastatin is formed when rosuvastatin undergoes demethylation, primarily by the cytochrome P450 (CYP) is...
T35513 13C15-Nivalenol 13C15-Nivalenol
13C15-Nivalenol is intended for use as an internal standard for the quantification of nivalenol by GC- or LC-MS. Nivalenol is a trichothecene mycotoxin that has been found inFusarium.1It is lethal to mice (LD50= 6.9 mg/k...
T71300 Pentoxifylline-d6
Pentoxifylline-d6 is intended for use as an internal standard for the quantification of pentoxifylline by GC- or LC-MS. Pentoxifylline is a hemorrheologic agent. It increases the deformability of washed isolated human er...
T36660 Olsalazine-13C6 Olsalazine-13C6
Olsalazine-13C6is intended for use as an internal standard for the quantification of olsalazine by GC- or LC-MS. Olsalazine is an orally bioavailable prodrug form of the anti-inflammatory agent 5-aminosalicylic acid that...
T36070 (±)5(6)-EET
5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5(6)-EET degrades into 5,6-DiHET and 5(6)-δ-lactone, which can be converted to 5...
T70960 Maprotiline-d3 hydrochloride
Maprotiline-d3 is intended for use as an internal standard for the quantification of maprotiline by GC- or LC-MS. Maprotiline is a tricyclic antidepressant. It binds to the norepinephrine transporter (NET) and is selecti...
T71981 Gliclazide-d4
Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. ...
T36408 Rhein-13C4 Rhein-13C4
Rhein-13C4 is intended for use as an internal standard for the quantification of rhein by GC- or LC-MS. Rhein is an anti-inflammatory anthraquinone found in rhubarb and is the bioactive derivative of its prodrug diacerei...
T38118 Zanamivir-13C,15N2 Zanamivir-13C,15N2
Zanamivir-13C,15N2is intended for use as an internal standard for the quantification of zanamivir by GC- or LC-MS. Zanamivir is a sialic acid analog that inhibits neuraminidase release of newly replicated influenza virus...
T35783 Zearalenone-13C18 Zearalenone-13C18
Zearalenone-13C18is intended for use as an internal standard for the quantification of zearalenone by GC- or LC-MS. Zearalenone is a mycotoxin that has been found inFusariumand has estrogenic activities.1It binds to huma...
T71401 Oxaliplatin-d10
Oxaliplatin-d10 is intended for use as an internal standard for the quantification of oxaliplatin by GC- or LC-MS. Oxaliplatin is a platinum-containing DNA-crosslinking agent. It induces the formation of DNA inter- and i...
T35695 Oleic Acid-13C
Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been fo...
T35517 4-deoxy Nivalenol-13C15 4-deoxy Nivalenol-13C15
4-deoxy Nivalenol-13C15is intended for use as an internal standard for the quantification of 4-deoxy nivalenol by GC- or LC-MS. 4-deoxy Nivalenol is a trichothecene mycotoxin that has been found inFusarium.1It binds to e...
T71328 Theobromine-d6
Theobromine-d6 is intended for use as an internal standard for the quantification of theobromine by GC- or LC-MS. Theobromine is a methylxanthine alkaloid and derivative of caffeine that has been found in cocoa beans and...
T36844 Inostamycin A
Inostamycin A is a bacterial metabolite that has been found inStreptomycesand has anticancer activity.1It is an inhibitor of CDP-diacylglycerol:inositol 3-phosphatidyltransferase (IC50= 0.02 μg/ml in A431 cell membranes)...
T69966 Roxadustat-d5
Roxadustat-d5 is intended for use as an internal standard for the quantification of roxadustat by GC- or LC-MS. Roxadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH; IC50s = 1.4, 1.26, and 1....
T70313 Indoxyl Sulfate-d5 potassium salt
Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of in...
T35591 Guanfacine-13C,15N3 Guanfacine-13C,15N3
Guanfacine-13C,15N3is intended for us as an internal standard for the quantification of guanfacine by GC- or LC-MS. Guanfacine is an α2-adrenergic receptor (α2-AR) agonist with Kivalues of 93, 1,380, and 3,890 nM for α2A...
T35775 HT-2 Toxin-13C22 HT-2 Toxin-13C22
HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene...
T35789 Palmitic acid-1-13C
Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plas...
T35683 2-deoxy-D-Glucose-13C6 2-deoxy-D-Glucose-13C6
2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits h...
T35791 Palmitic acid-13C
Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid i...
T36881 NHC-diphosphate triammonium
NHC-triphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form[1]. NHC-triphosphate triammonium is a weak alternative substrate for the viral poly...
T36903 Rasagiline-13C3 (mesylate) Rasagiline-13C3 (mesylate)
Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is se...
T38297 Ribavirin-13C5 Ribavirin-13C5
Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to a...
T35929 O-Demethyl Apremilast
O-Demethyl apremilast is an active metabolite of the phosphodiesterase 4 (PDE4) inhibitor apremilast .1It inhibits the activity of PDE4 isolated from U937 cells and LPS-induced TNF-α production in isolated human peripher...
T37847 Zonisamide-13C2,15N Zonisamide-13C2,15N
Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels ...

Compounds

Propargyl-PEG5-Ms
T18588
Synonym: Propargyl-PEG6-Ms
Target: Others, PROTAC Linker
ms48107
T9146
Synonym: Benzenemethanol, 2-[4-amino-6-[[(4-phenoxyphenyl)methyl]amino]-1,3,5-triazin-2-yl]-3-fluoro-
Target: Others
Benzyl-PEG5-Ms
T14541
Synonym:
Target: Others
m-PEG5-Ms
T15894
Synonym:
Target: Others
Boc-N-Amido-PEG5-Ms
T17650
Synonym:
Target: Others
Ms-PEG5-t-butyl ester
T16150
Synonym: Ms-PEG4-t-butyl ester
Target: Others
Ozanimod
T6923
Synonym: RPC-1063
Target: S1P Receptor, LPL Receptor
MS 245 oxalate
T23029
Synonym:
Target: Others
S1P1 agonist 5
T62732
Synonym:
Target:
5-Fluorouracil-13C,15N2
T36895
Synonym: 5-Fluorouracil-13C,15N2
Target:
MS 39
T41156
Synonym:
Target:
Caffeic Acid-13C3
T38037
Synonym: Caffeic Acid-13C3
Target:
Rizatriptan-d6 benzoate salt
T71211
Synonym:
Target:
(±)5(6)-DiHET lactone
T36556
Synonym:
Target:
Norfluoxetine-d5 HCl
T71302
Synonym:
Target:
Clobetasol Propionate-d5
T71893
Synonym:
Target:
N-desmethyl Rosuvastatin (sodium salt hydrate)
T35718
Synonym:
Target:
13C15-Nivalenol
T35513
Synonym: 13C15-Nivalenol
Target:
Pentoxifylline-d6
T71300
Synonym:
Target:
Olsalazine-13C6
T36660
Synonym: Olsalazine-13C6
Target:
(±)5(6)-EET
T36070
Synonym:
Target:
Maprotiline-d3 hydrochloride
T70960
Synonym:
Target:
Gliclazide-d4
T71981
Synonym:
Target:
Rhein-13C4
T36408
Synonym: Rhein-13C4
Target:
Zanamivir-13C,15N2
T38118
Synonym: Zanamivir-13C,15N2
Target:
Zearalenone-13C18
T35783
Synonym: Zearalenone-13C18
Target:
Oxaliplatin-d10
T71401
Synonym:
Target:
Oleic Acid-13C
T35695
Synonym:
Target:
4-deoxy Nivalenol-13C15
T35517
Synonym: 4-deoxy Nivalenol-13C15
Target:
Theobromine-d6
T71328
Synonym:
Target:
Inostamycin A
T36844
Synonym:
Target:
Roxadustat-d5
T69966
Synonym:
Target:
Indoxyl Sulfate-d5 potassium salt
T70313
Synonym:
Target:
Guanfacine-13C,15N3
T35591
Synonym: Guanfacine-13C,15N3
Target:
HT-2 Toxin-13C22
T35775
Synonym: HT-2 Toxin-13C22
Target:
Palmitic acid-1-13C
T35789
Synonym:
Target:
2-deoxy-D-Glucose-13C6
T35683
Synonym: 2-deoxy-D-Glucose-13C6
Target:
Palmitic acid-13C
T35791
Synonym:
Target:
NHC-diphosphate triammonium
T36881
Synonym:
Target:
Rasagiline-13C3 (mesylate)
T36903
Synonym: Rasagiline-13C3 (mesylate)
Target:
Ribavirin-13C5
T38297
Synonym: Ribavirin-13C5
Target:
O-Demethyl Apremilast
T35929
Synonym:
Target:
Zonisamide-13C2,15N
T37847
Synonym: Zonisamide-13C2,15N
Target:
Cat No. Product Name Synonyms Targets
T5888 5-Methoxysalicylic acid 5-MeOSA Others
5-Methoxysalicylic acid (5-MeOSA), a natural product, serves as an effective matrix for oligonucleotide analysis in MALDI MS when used alongside spermine.
TN3135 5-O-Methylnaringenin Others
5-O-Methylnaringenin is a marker, reduced MS detection of 5-O-methylnaringenin indicated that nifedipine may preferably remove a proton from the 5-position OH group in the A ring of the flavonoid skeleton.
T36791 Lysophosphatidylcholine 18:2
1-Linoleoyl-2-hydroxy-sn-glycero-3-PC (LGPC) is a lysophospholipid containing linoleic acid at thesn-1 position that has been found in mouse heart, lung, liver, spleen, kidney, plasma, and serum.1Serum levels of LGPC dec...

Natural Products

5-Methoxysalicylic acid
T5888
Synonym: 5-MeOSA
Target: Others
5-O-Methylnaringenin
TN3135
Synonym:
Target: Others
Lysophosphatidylcholine 18:2
T36791
Synonym:
Target:

Recombinant Proteins

Species：
Human (10)
Cynomolgus (1)
Expression System：
HEK293 Cells (10)
E. coli (1)
Tag：
C-hFc (5)
C-His (2)
C-His-Avi (2)
His (1)
N-6xHis (1)
Cat No. Product Name Species Expression System
TMPY-01459 TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) Human HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P19438-1.
TMPK-00564 TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of...
TMPY-05475 TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc) Human HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P19438-1.
TMPY-05308 CD45 Protein, Human, Recombinant (aa 1-529, His) Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPJ-00854 ETS1 Protein, Human, Recombinant (His) Human E. coli
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or ...
TMPY-05498 SR-BI/SCARB1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
TMPY-05387 SLAMF7 Protein, Human, Recombinant (hFc) Human HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-05547 SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated Human HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-04318 GRIK2 Protein, Human, Recombinant (hFc) Human HEK293 Cells
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar...
TMPK-01363 SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
TMPK-01357 SIRP alpha V5 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
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