Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-δ-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS. 5,6-DiHET potently induces vasodilation of isolated canine coronary arterioles, with 41 and 100% inhibition occurring at 0.01 and 100 pM, respectively. It also induces vasodilation in isolated human microvessels and increases intracellular calcium levels in a dose-dependent manner, an effect that can be blocked by the nitric oxide scavenger L-NAME .
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 μg | 35 days | $ 230.00 | |
50 μg | 35 days | $ 435.00 | |
100 μg | 35 days | $ 793.00 | |
250 μg | 35 days | $ 1,790.00 |
Description | 5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-δ-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS. 5,6-DiHET potently induces vasodilation of isolated canine coronary arterioles, with 41 and 100% inhibition occurring at 0.01 and 100 pM, respectively. It also induces vasodilation in isolated human microvessels and increases intracellular calcium levels in a dose-dependent manner, an effect that can be blocked by the nitric oxide scavenger L-NAME . |
Molecular Weight | 320.473 |
Formula | C20H32O3 |
CAS No. | 213126-92-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: >50 mg/mL (per Rao Maddipati)
Ethanol: >50 mg/mL (per Rao Maddipati)
PBS (pH 7.2): >1 mg/mL (from 13(S)-HODE)
DMSO: >50 mg/mL (per Rao Maddipati)
You can also refer to dose conversion for different animals. More
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(±)5(6)-DiHET lactone 213126-92-2 5(6)-DiHET lactone (±)5(6)DiHET lactone (±)5(6) DiHET lactone inhibitor inhibit