Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Zanamivir-13C,15N2is intended for use as an internal standard for the quantification of zanamivir by GC- or LC-MS. Zanamivir is a sialic acid analog that inhibits neuraminidase release of newly replicated influenza virus particles.1It has been shown to selectively inhibit the growth of influenza A and B viruses in plaque reduction assays with IC50values ranging from 5 to 14 nM and to directly inhibit influenza A and B virus neuraminidases with IC50values ranging from 0.6 to 7.9 nMin vitro. Intranasal zanamivir administration at 0.4 mg/kg twice daily reduces mortality and viral titers in lung homogenates of mice infected with influenza.
Pack Size | Availability | Price/USD | Quantity |
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1 mg | Inquiry | $ 1,524.00 |
Description | Zanamivir-13C,15N2is intended for use as an internal standard for the quantification of zanamivir by GC- or LC-MS. Zanamivir is a sialic acid analog that inhibits neuraminidase release of newly replicated influenza virus particles.1It has been shown to selectively inhibit the growth of influenza A and B viruses in plaque reduction assays with IC50values ranging from 5 to 14 nM and to directly inhibit influenza A and B virus neuraminidases with IC50values ranging from 0.6 to 7.9 nMin vitro. Intranasal zanamivir administration at 0.4 mg/kg twice daily reduces mortality and viral titers in lung homogenates of mice infected with influenza. |
Synonyms | Zanamivir-13C,15N2 |
Molecular Weight | 335.292 |
Formula | C12H20N4O7 |
CAS No. | 1276528-62-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: Slightly soluble
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Zanamivir-13C,15N2 1276528-62-1 Zanamivir 13C,15N2 Zanamivir-13C,15N-2 Zanamivir13C,15N2 inhibitor inhibit