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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21897L | MPP hydrochloride | MPP hydrochloride (289726-02-9 Free base) | Estrogen Receptor/ERR |
MPP hydrochloride is a selective estrogen receptor (ERR) modulator. | |||
T9169 | MPP+ iodide | Mitochondrial Metabolism , Autophagy | |
MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) ex... | |||
T12101 | MPP dihydrochloride (289726-02-9 Free base) | Others | |
MPP dihydrochloride is a highly selective antagonist of estrogen receptor alpha (ERα). | |||
T16421 | P-MPPI hydrochloride | 5-HT Receptor | |
p-MPPI hydrochloride is a selective antagonist of 5-HT1A receptor, and has antidepressant and anxiolytic-like effects. | |||
T4058 | R-IMPP | Others , Serine/threonin kinase | |
R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin. | |||
T14280 | AMPPD | Lumigen PPD,3-(2'-Spiroadamantane)-4-methoxy-4-(3''-phosphoryloxy)phenyl-1,2-dioxetane,PPD,Lumi-Phos Plus | Others |
AMPPD (Lumi-Phos Plus) is a 1,2-dioxo-cyclohexane derivative and a substrate for hypersensitive alkaline phosphatase. | |||
T28077 | MMPP | VEGFR , STAT | |
MMPP is a novel VEGFR2 inhibitor with anti-inflammatory and potential anticancer activity, inhibits STAT3, inhibits angiogenesis via VEGFR2/AKT/ERK/NF-kappaB pathway, and can be used to alleviate myocardial injury. | |||
T23043 | N-MPPP Hydrochloride | Others | |
High affinity κ agonist | |||
T37893 | 3-MPPI | ||
3-MPPI was a high-affinity nonselective α1-antagonist. | |||
T38212 | MPPG | ||
MPPG is a selective L-AP4-sensitive receptor antagonist (kD=9.2 μM). | |||
T22497 | 2-MPPA | Others | |
glutamate carboxypeptidase II (GCP II) inhibitor | |||
T69750 | P-MPPF dihydrochloride | ||
p-MPPF dihydrochloride is a selective 5-ht1a serotonin receptor antagonist | |||
T28986 | TMPPAA | ||
TMPPAA is an allosteric agonist of 5-HT3 receptor. | |||
T33493 | Mppf F-18 | J1.050.795B,P-18FMPPF,(18F) Mppf,(18F)Mppf,(18F)-Mppf | |
Mppf F-18, which has been used as a radioactive ligand for positron emission tomography, is a compound that binds to the serotonin-1A receptor. | |||
T26766 | BemPPOX | ||
BemPPOX is a potent inhibitor of DGL. | |||
T40063 | CBR-470-1 | Nrf2 | |
CBR-470-1 is a potent inhibitor of glycolytic phosphoglycerate kinase 1 (PGK1) that activates NRF2 by increasing methylglyoxal levels. CBR-470-1 is a non-covalent Nrf2 activator with neuroprotective activity that protect... | |||
T4081 | MPTP hydrochloride | MPTP-hydrochloride | Apoptosis , Dopamine Receptor |
MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability. MPTP hydrochloride is toxic to dopaminergic neurons, which can lead to Parkinson's disease, and is widely used in th... | |||
T3570 | SU4312 | SU 4312,NSC 86429 | VEGFR , PDGFR |
SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). SU4312 (SU 4312) unexpectedly protects against MPP(+) -induced neurotox... | |||
T2860 | Vanillyl Alcohol | 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,Vanillin alcohol,Vanillic alcohol | Apoptosis , Others |
Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant, neuroprotective, and anti-nociceptive activities. Vanillyl alcohol can effectively inhibit ... | |||
TN1038 | Galgravin | Apoptosis | |
Galgravin has anti-inflammatory, and neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloid beta peptide (Abeta25-35)-induced cytotoxicity, and protec... |