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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0875 | Acetylcysteine | N-Acetyl-L-cysteine,LNAC,NAC | Apoptosis , TNF , Ferroptosis , Influenza Virus , Reactive Oxygen Species , ROS , Endogenous Metabolite |
Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent. Acetylcysteine induces apoptosis, can be used to reduce mucus thickness, and has anti-influenza viral activity. | |||
T6090 | Belnacasan | VX-765 | Caspase |
Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor. | |||
T12282 | Benzyl-α-GalNAc | O-glycosylation-IN-1 | Others |
Benzyl-α-GalNAc (O-glycosylation-IN-1) is a potent inhibitor of O-glycosylation and is used to reduce mucin on cell surfaces. | |||
T1189 | Milnacipran hydrochloride | Milnacipran HCl,Savella,Dalcipran | Serotonin Transporter , Norepinephrine |
Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Milnacipran hydrochloride is an enantiomer of milnacipran, which is used to treat fibromy... | |||
T7940 | Milnacipran ((1S-cis) hydrochloride) | Levomilnacipran Hydrochloride | Serotonin Transporter |
Milnacipran (1S-cis) hydrochloride (Levomilnacipran Hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI), treatment of fibromyalgia. | |||
T7643 | Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH | Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH,Fmoc-Ser(Ac3AcNH-α-Gal)-OH,Fmoc-Ser[GalNAc(Ac)3-α-D]-OH | Others |
Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH (Fmoc-Ser(Ac3AcNH-α-Gal)-OH) is an anti-tumor drug | |||
T39370 | Tri-GalNAc-COOH | LYTACs | |
Tri-GalNAc-COOH is a ligand for the asialoglycoprotein receptor (ASGPR) commonly employed in Lysosome Targeting Chimera (LYTAC) investigations. | |||
T2594 | Dextromilnacipran | Levomilnacipran | Serotonin Transporter , Norepinephrine |
Dextromilnacipran (Levomilnacipran) is a selective serotonin and norepinephrine reuptake inhibitor. | |||
T77945 | TriGalNAc CBz | LYTACs | |
TriGalNAc CBz is a GalNAc derivative. As an ASGPR ligand, tri-GalNAc targets lysosomes in mRNA drug delivery and LYTAC studies.L-DABA hydrobromide. | |||
T24755 | Salnacedin | G-201,SCY,G-201,G201,SCY,G 201 | Others |
Salnacedin (G-201) is a small molecule compound used in the treatment of immune system disorders, skin and musculoskeletal disorders, and can be used in studies of acne vulgaris, dermatitis and psoriasis. | |||
T77941 | Tri-GalNAc biotin | LYTACs | |
Tri-GalNAc biotin, a small molecule lysosome targeting degrader, serves as a ligand for the asialoglycoprotein receptor (ASGPR). It promotes the uptake of NeutrAvidin (NA) into liver cells via ASGPR and directs NeutrAvid... | |||
T80946 | Tri-GalNAc-NHS ester | LYTACs | |
Tri-GalNAc-NHS ester, a LYsosome TArgeting Chimera (LYTAC) and ligand for the asialoglycoprotein receptor (ASGPR), facilitates the degradation of extracellular proteins, including membrane proteins, via the lysosomal tar... | |||
T80947 | Tri-GalNAc-COOH (acetylation) | LYTACs | |
Tri-GalNAc-COOH acetylation represents the acetylated derivative of tri-galactosamine (tri-GalNAc-COOH), utilized in the synthesis of lysosome targeting chimeras (LYTAC). | |||
T78452 | X-GalNAc | ||
X-GalNAc is a chromogenic substrate utilized for the detection of N-acetyl-β-galactosidase activity, facilitating the determination of cloned DNA insert presence in bacteria cultured on agar plates [1]. | |||
T74877 | GalNAc unconjugated/naked Fitusiran | ||
GalNAc unconjugated/naked Fitusiran, an small interfering RNA without GalNAc conjugation, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. GalNAc unconjugated/naked Fitusiran i... | |||
T74876 | GalNAc unconjugated/naked Inclisiran | ||
Inclisiran (unconjugated/naked) is a double-stranded small interfering RNA (siRNA) that lacks GalNAc conjugation. This compound selectively inhibits the transcription of PCSK-9, making it applicable in the research of hy... | |||
T35045 | Velnacrine | 1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate,1-hydroxytacrine,9-ATHCO,9-amino-1,2,3,4-tetrahydroacridin-1-ol | Others |
Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical. | |||
T7073 | Milnacipran | ||
Milnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Milnacipran is well absorbed after oral dosing and has a bioavailability of 85%. | |||
T16570 | Pralnacasan | VX-740,HMR 3480 | Others |
Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan is an effective, non-peptide, and orally active interleukin-1β converting enzyme inhibitor (Ki: 1.4 nM). Pralnacasan has the potential ... | |||
T73809 | UDP-GalNAc disodium | ||
UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium, a sugar nucleotide, serves as a substrate for EpsC115, an exopolymeric substances (EPS) N-terminal deletion mutant characterized by the absence of residues 1-115. Addit... |