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Search Results for " larg "

20

Compounds

7

Natural Products

7

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T37053 Z-(L-Arg)-AMC (hydrochloride)
Z-(L-Arg)-AMC is a fluorogenic substrate for trypsin, cathepsin B, and cathepsin H.1,2Upon enzymatic cleavage by trypsin, cathepsin B, or cathepsin H, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can b...
T7510 Leucylarginylproline RAAS
Leucylarginylproline is an inhibitor of angiotensin-converting enzyme (ACE) (IC50 : 0.27μM).
TP1830 SV40 large T antigen NLS
SV40 large T antigen NLS is from Large T antigen residue 47 to 55, enables protein import into cell nucleus. This peptide is generated from Large T antigen residue 47 to 55.
T29669 ADP-Ribosylarginine alpha-ADP-ribosylarginine
ADP-Ribosylarginine can regulate cell proliferation and tumorigenesis.
T25630 Largazole
Largazole is a potent and selective histone deacetylase (HDAC) inhibitor and antiproliferative agent from Symploca.
T73688 Insulin glargine
Insulin glargine, a long-acting insulin analog, is utilized for the treatment of diabetes mellitus [1].
T73404 Dalargin
Dalargin, a potent δ-opioid receptor agonist, demonstrates efficacy in mitigating cell death induced by Gentamicin and exhibits nephroprotective effects against Gentamicin-induced kidney injury. Additionally, Dalargin po...
TP2183 Large T antigen - rhesus polyomavirus 560-568 Others
Large T antigen - rhesus polyomavirus 560-568 has a peptide sequence of Ser-Glu-Phe-Leu-Leu-Glu-Lys-Arg-Ile. T antigen is required for viral DNA replication, transcription, and virion assembly.
TP1830L SV40 large T antigen NLS acetate Others
SV40 large T antigen NLS acetate is from Large T antigen residue 47 to 55, enables protein import into cell nucleus.
T83194 Acetylarginyltryptophyl diphenylglycine
Acetylarginyltryptophyl diphenylglycine, a bioactive peptide, exhibits anti-aging properties and has been documented as a cosmetic ingredient [1].
T36079 Tripelargonin
Tripelargonin is a triacylglycerol that contains nonanoic acid at the sn-1, sn-2, and sn-3 positions. It has been found in Schizochytrium biomass.1 Tripelargonin increases blood levels of the ketone body D-(-)-3-hydroxyb...
T25684 Leucylarginine Leu-arg,Leucyl-arginine
Leucylarginine hinders antinociception induced by L-arginine.
T30411 Benzoylarginine leucinamide
Benzoylarginine leucinamide is a dipeptide.
T26277 Tilarginine omega-N-Methylarginine,N-Methylarginine,L-NMMA,546C88
Tilarginine is a nitric oxide synthetase competitive inhibitor.
T26277L Tilarginine citrate L-Ng-monomethyl arginine citrate
Tilarginine citrate is a competitive nitric oxide synthetase inhibitor.
T3553 Y16 Rho , Ras
Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated signaling functions.
T16745 Rhosin hydrochloride Apoptosis , Rho , Ras
Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin hydrochloride does not interact with Cdc42 o...
T16746 Rhosin Rho
Rhosin is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin does not interact with Cdc42 or Rac1, nor the GEF, LARG. R...
TP2327L Y16 acetate(429653-73-6 free base) Y16 acetate(53-73-6 free base),ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE acetate Rho
Y16 acetate(429653-73-6 free base) is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated signaling functions.
T32849 Loline
Loline is a natural insecticidal and deterrent to a broad range of insects, including species in the Hemiptera, Coleoptera, Hymenoptera, Lepidoptera, and Blattodea orders. Loline deters species such as the bird cherry-oa...
Cat No. Product Name Synonyms Targets
T7682 Asymmetric dimethylarginine Endogenous Metabolite , NO Synthase , NOD
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
TN1058 Pelargonidin chloride NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway.
TN2044 Pelargonidin-3,5-O-diglucoside chloride Others
Pelargonidin-3,5-O-diglucoside chloride has antioxidant activity.
TN2045 Pelargonidin-3-O-glucoside chloride Others , Estrogen/progestogen Receptor
Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. Pelargonidin-3-O-glucopyranoside has antioxidant, anti-inflammatory, anti-estrogenic, and angiotensin-converting enzyme ...
T81523 Pelargonidin 3-galactoside chloride
Pelargonidin 3-galactoside chloride, a predominant anthocyanin, exhibits anticancer properties and inhibits α-glucosidase [1].
TN6618 Pelargonidin-3-O-rutinosde chloride
Pelargonidin 3-Rutinoside exhibits antioxidant and anti-inflammatory properties.
T81939 Leucopelargonidin
Leucopelargonidin (compound IV), extracted from Connarus monocarpus [1], is an isolate.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-02041 ARHGEF12 Protein, Human, Recombinant (His) Human E. coli
ARHGEF12 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-00360 DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant Cenarchaeum symbiosum E. coli
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicativ...
TMPH-00773 RuBisCO large subunit Protein, Glycine max, Recombinant (His & SUMO) Glycine max E. coli
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration pro...
TMPH-01192 Human cytomegalovirus (HCMV) (strain AD169) Large structural phosphoprotein (Avi & His & MBP), Biotinylated HHV-5 E. coli
Human cytomegalovirus (HCMV) (strain AD169) Large structural phosphoprotein (Avi & His & MBP), Biotinylated is expressed in E. coli.
TMPH-00810 Hepatitis delta virus genotype I (HDV) Large delta antigen Protein (His & Myc) HDV P. pastoris (Yeast)
Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. Needs co-infection with hepatitis B virus to provide surface proteins, otherwise there is no packaging ...
TMPH-00816 HBV-A subtype adw2 (strain Rutter 1979) Large envelope protein (His) HBV-A E. coli
HBV-A subtype adw2 (strain Rutter 1979) Large envelope protein (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 45.1 kDa and the accession number is P03141.
TMPH-02697 GNA12 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF12/LARG). G...
TargetMol