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Tilarginine citrate

Catalog No. T26277L CAS 209913-88-2

Synonyms: L-Ng-monomethyl arginine citrate

Tilarginine citrate is a competitive nitric oxide synthetase inhibitor.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Tilarginine citrate, CAS 209913-88-2

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Tilarginine citrate is a competitive nitric oxide synthetase inhibitor.

Synonyms	L-Ng-monomethyl arginine citrate
Molecular Weight	380.354
Formula	C13H24N4O9
CAS No.	209913-88-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Ricciardolo FL, Rado V, Fabbri LM, Sterk PJ, Di Maria GU, Geppetti P. Bronchoconstriction induced by citric acid inhalation in guinea pigs: role of tachykinins, bradykinin, and nitric oxide. Am J Respir Crit Care Med. 1999 Feb;159(2):557-62. PubMed PMID: 9927373. 2. Kimura M, Higashi Y, Hara K, Noma K, Sasaki S, Nakagawa K, Goto C, Oshima T, Yoshizumi M, Chayama K. PDE5 inhibitor sildenafil citrate augments endothelium-dependent vasodilation in smokers. Hypertension. 2003 May;41(5):1106-10. Epub 2003 Apr 14. PubMed PMID: 12695418. 3. Kaluski E, Uriel N, Milo-Cotter O, Klapholz M. Nitric oxide synthase inhibitors in cardiogenic shock: present and future. Future Cardiol. 2008 Mar;4(2):183-9. doi: 10.2217/14796678.4.2.183. PubMed PMID: 19804295. 4. Clancy RM, Gomez PF, Abramson SB. Nitric oxide sustains nuclear factor kappaB activation in cytokine-stimulated chondrocytes. Osteoarthritis Cartilage. 2004 Jul;12(7):552-8. PubMed PMID: 15219570.

Dose Conversion

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Tilarginine citrate 209913-88-2 Tilarginine Citrate L-Ng-monomethyl arginine Citrate L-Ng-monomethyl arginine citrate inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.