il-1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T11635	IL-17A antagonist 1		IL Receptor
	IL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.		IL Receptor
T36527	IL-4-inhibitor-1		IL Receptor
	IL-4 inhibitor is an inhibitor of IL-4.1It binds to IL-4 with a Kdvalue of 1.8 μM and inhibits IL-4 activity in a cell-based reporter assay (EC50= 1.81 μM). It is selective for IL-4 over IL-13 (EC50= 18.2 μM). IL-4 inhib...		IL Receptor
T9448	IL-17A inhibitor 1		IL Receptor
	IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.		IL Receptor
T11634	IL-15-IN-1		IL Receptor , Interleukin
	IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).		IL Receptor , Interleukin
T40354	IL-17A modulator-1
	IL-17A modulator-1 is an effective inhibitor of IL-17A activity, exhibiting a pIC 50 value of 8.2. This compound holds great promise for studying diseases and disorders that involve the modulation of IL-17A, such as immu...
T36525	IL-17 modulator 1 disodium
	IL-17 Modulator 1 (disodium) is a potent, orally active compound, known for its high efficacy in modulating IL-17. This compound is extensively utilized for researching various diseases such as psoriasis, ankylosing spon...
T62183	IL-2-IN-1
	IL-2-IN-1 is a potent inhibitor of IL-2 (IC50: 1978 nM) and exhibits anti-proliferative effects.
T5094	IRAK inhibitor 1		IRAK , JNK
	IRAK inhibitor 1 is an effective IRAK-4 inhibitor (IC50: 216 nM), is poorly active against JNK-1 (IC50: 3.801 μM) and JNK-2 (IC50>10 μM).		IRAK , JNK
T4140	IRAK4-IN-1		IRAK
	IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.		IRAK
T9631	IRAK-4 protein kinase inhibitor 2		IRAK
	IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).		IRAK
T4050	GSK2981278	ROR gama modulator 1	ROR
	GSK2981278 (ROR gama modulator 1) is a highly potent and selective inverse agonist of retinoic acid receptor-related orphan receptor gamma (ROR gamma).		ROR
T2457	IRAK-1-4 Inhibitor I	IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor	IRAK
	IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.		IRAK
T5110	IRAK inhibitor 6		IRAK
	IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).		IRAK
T9027	CA-4948	Emavusertib	IRAK , FLT
	CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.		IRAK , FLT
T22698	TLR3-IN-1	CU CPT 4a	TLR
	TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor (IC50: 3.44 μM in RAW 264.7 cells). It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-α and IL-1β in whole cell...		TLR
T14367	AZ1495		IRAK , CDK , Haspin Kinase
	AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffu...		IRAK , CDK , Haspin Kinase
T4299	AS-2444697		IRAK
	AS-2444697 is an inhibitor of IRAK-4 (C50 = 21 nM). AS-2444697 exhibits renoprotective effects through anti-inflammatory action. AS-2444697 potently inhibits human and rat IRAK-4 activity.		IRAK
TQ0167	Zimlovisertib	PF-06650833,PF06650833	IRAK
	Zimlovisertib (PF-06650833) is an effective, selective and orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) (IC50s: 0.2 and 2.4 nM in the cell and PBMC assay).		IRAK
T11673	IRAK4-IN-4		IRAK , cGAS
	IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.		IRAK , cGAS
T9203	JH-X-119-01		IRAK
	JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1.		IRAK