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IRAK4-IN-4

Catalog No. T11673 CAS 1850276-58-2

IRAK4-IN-4 inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.

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IRAK4-IN-4, CAS 1850276-58-2

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	IRAK4-IN-4 inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.
Targets&IC50	cGAS:2.1 nM (IC50), IRAK4:2.8 nM (IC50)

Molecular Weight	340.37
Formula	C22H16N2O2
CAS No.	1850276-58-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 24 mg/mL(70.51 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. One class has the naphthalene second dione compounds and its derivative of protease modification activities. CN107163044A.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Covalent Inhibitor Library Kinase Inhibitor Library Bioactive Compound Library

Related Products

Related compounds with same targets

G140 RU.521 PF-06928215 IRAK4-IN-4 G150

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

IRAK4-IN-4 1850276-58-2 NF-Kb信号通路免疫与炎症 cGAS IRAK inhibit Inhibitor IL-1R associated kinase IRAK4IN4 Cyclic GMP-AMP Synthase IRAK-4-IN-4 Interleukin-1 receptor associated kinase IRAK4 IN 4 inhibitor

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