glut1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T74962	GLUT1-IN-1
	GLUT1-IN-1, a glucose transporter 1 (GLUT1) inhibitor, possesses specific inactivation capability for GLUT1. This compound demonstrates concentration-dependent cytotoxicity towards HeLa, A549, and HepG2 cells, with IC50 ...
T82294	GLUT1-IN-3
	GLUT1-IN-3 (Compd 4b), a compound under investigation for type 1 glucose transporter deficiency syndrome, effectively inhibits seizures [1].
T9558	KL-11743		transporter
	KL-11743 specifically blocks glucose metabolism, triggering an acute collapse in NADH pools and a striking accumulation of aspartate, indicating a dramatic shift toward oxidative phosphorylation in the mitochondria.		transporter
T2363	STF-31		transporter , Autophagy
	STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.		transporter , Autophagy
T4182	Lavendustin B		Tyrosinase , transporter , HIV Protease
	Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75).		Tyrosinase , transporter , HIV Protease
TN1911	Marein		transporter , Akt , HDAC , AMPK
	Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for ...		transporter , Akt , HDAC , AMPK
T9352	Hydrocotarnine		Others
	hydrocotarnine is an inhibitor of Cbl.		Others
T3713	BAY-876		transporter
	BAY-876 is an orally active and selective inhibitor of glucose transporter 1 (GLUT1, IC50= 2 nM). BAY-876 exhibits >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 also inhibits glycolytic metabol...		transporter
T7018	WZB117		transporter
	WZB117 is a Glucose Transporter 1 (GLUT1) inhibitor. when IC50 of WZB117 approximate 10 μM, it inhibits lung cancer A549 cells and breast cancer MCF7 cells proliferation.		transporter
T14327	AS1949490		Phosphatase
	AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM.		Phosphatase
T8616	Fasentin	N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide	transporter
	Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1.		transporter
T19663	Triheptanoin	UX 007,IND106011,UX007,UX-007,IND 106011,IND-106011	Others
	Triheptanoin (IND 106011) is a fatty acid metabolic modulator. It potentially for the treatment of fatty acid oxidation disorders and GLUT1.		Others
T61695	GLUT4-IN-2
	GLUT4-IN-2, a selective inhibitor specifically targeting GLUT4, demonstrates potent antitumor activity with IC50 values of 6.8 μM for GLUT4 and 11.4 μM for GLUT1. It effectively induces cell apoptosis and arrests the cel...
T40083	GLUT inhibitor-1		transporter
	GLUT inhibitor-1 is an orally active GLUT inhibitor with IC50 s of 242 nM and 179 nM for GLUT1 and GLUT3. GLUT inhibitor-1 can be used in studies about cancers and autoimmune diseases.		transporter
T26743	BAY-588	BAY 588	Others
	BAY-588 is an inactive control probe of BAY-876 which is an inhibitor of GLUT1.		Others
T69767	NV-5440
	NV-5440 is a novel cell penetrant, potent and selective class I glucose transporters (GLUT1) inhibitor, selectively inhibiting mTORC1
T25111	AS1938909	AS 1938909,AS-1938909
	AS1938909 is a SHIP2 inhibitor that works by increasing Akt phosphorylation, glucose consumption, and glucose uptake in L6 myotubes, specifically upregulating the GLUT1 gene.
T72172	4,6-O-Ethylidene-α-D-glucose	Ethylidene-glucose
	4,6-O-Ethylidene-α-D-glucose (Ethylidene-glucose), a derivative of glucose, serves as a competitive inhibitor for the exofacial binding site of glucose transporter 1 (GLUT1), exhibiting a Ki of 12 mM against wild-type 2-...
T68511	KRH102140
	KRH102140 is a potent activator of PHD2. KRH102140, which has a structure similar to KRH102053. KRH102140 more efficiently suppressed HIF-1α than KRH102053 in human osteosarcoma cells under hypoxia. Furthermore, KRH10214...