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Search Results for " g12 "

20

Compounds

Cat No. Product Name Synonyms Targets
T39099 G12 Ras 5-17
G12 (Ras 5-17) is a wild-type Ras peptide composed of amino acids 5-17, specifically KLVVVGAGGVGKS. It can serve as a control in studies focused on mutant Ras peptides, like V12.
T17408 Amino-PEG12-Boc Others , PROTAC Linker
Amino-PEG12-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
T17955 Fmoc-NH-PEG12-CH2CH2COOH Others , PROTAC Linker
Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker. Fmoc-NH-PEG12-CH2CH2COOH can be used in the synthesis of PROTAC.
T17561 Biotin-PEG12-NHS ester Others , PROTAC Linker
Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
T6711 Tyrphostin AG1296 Tyrphostin AG 1296,AG 1296 Apoptosis , FGFR , FLT , PDGFR , c-Kit
Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.
T11411 GLPG1205 GPR , Others
GLPG1205 is a potent, orally active GPR84 (G protein-coupled receptor) antagonist with anti-inflammatory activity. GLPG1205 shows good PK/PD characteristics and can be used to study pulmonary fibrosis.
T18143 M-PEG12-OH Dodecaethylene Glycol Monomethyl Ether Others , PROTAC Linker
m-PEG12-OH (Dodecaethylene Glycol Monomethyl Ether) is a PEG-based PROTAC linker. m-PEG12-OH can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of ant...
T17978 Fmoc-PEG12-NHS ester Others , PROTAC Linker
Fmoc-PEG12-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys...
T6555 K-Ras(G12C) inhibitor 12 Apoptosis , Raf , Ras
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).
T17407 Amino-PEG12-amine H2N-PEG12-CH2CH2NH2,PEODA13 Others , PROTAC Linker
Amino-PEG12-amine (H2N-PEG12-CH2CH2NH2) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
T17667 Boc-NH-PEG12-CH2CH2COOH Others , PROTAC Linker
Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
T17668 Boc-NH-PEG12-NH2 NHBoc-PEG12-amine Others , PROTAC Linker
Boc-NH-PEG12-NH2 (NHBoc-PEG12-amine) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
T17719 Cbz-NH-PEG12-C2-acid Others , PROTAC Linker
Cbz-NH-PEG12-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys...
T11738 K-Ras G12C-IN-4 Ras
K-Ras G12C-IN-4, is a potent Covalent Inhibitor of KRASG12C..
T78170 Kras4B G12D-IN-1 Ras
Kras4B G12D-IN-1 is an anticancer agent that functions as an inhibitor of the Kras4B G12D protein. It effectively reduces the expression of Kras protein in mouse embryonic fibroblasts (MEFs) harboring the Kras4B G12D mut...
T17464 Azide-PEG12-alcohol Others , PROTAC Linker
Azide-PEG12-alcohol is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
T15839 M-PEG12-amine Others
m-PEG12-amine is a PEG-based PROTAC linker and a non-cleavable 12 unit PEG ADC linker employed in the synthesis of PROTACs[1] and antibody-drug conjugates (ADCs)[2].
T18566 Propargyl-PEG12-bromide Others , PROTAC Linker
Propargyl-PEG12-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
T3725 K-Ras(G12C) Inhibitor 6 Raf
K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro.
T6556 K-Ras(G12C) inhibitor 9 Raf
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).
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TargetMol