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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T39099 | G12 | Ras 5-17 | |
G12 (Ras 5-17) is a wild-type Ras peptide composed of amino acids 5-17, specifically KLVVVGAGGVGKS. It can serve as a control in studies focused on mutant Ras peptides, like V12. | |||
T17408 | Amino-PEG12-Boc | Others , PROTAC Linker | |
Amino-PEG12-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis. | |||
T17955 | Fmoc-NH-PEG12-CH2CH2COOH | Others , PROTAC Linker | |
Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker. Fmoc-NH-PEG12-CH2CH2COOH can be used in the synthesis of PROTAC. | |||
T17561 | Biotin-PEG12-NHS ester | Others , PROTAC Linker | |
Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis. | |||
T6711 | Tyrphostin AG1296 | Tyrphostin AG 1296,AG 1296 | Apoptosis , FGFR , FLT , PDGFR , c-Kit |
Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR. | |||
T11411 | GLPG1205 | GPR , Others | |
GLPG1205 is a potent, orally active GPR84 (G protein-coupled receptor) antagonist with anti-inflammatory activity. GLPG1205 shows good PK/PD characteristics and can be used to study pulmonary fibrosis. | |||
T18143 | M-PEG12-OH | Dodecaethylene Glycol Monomethyl Ether | Others , PROTAC Linker |
m-PEG12-OH (Dodecaethylene Glycol Monomethyl Ether) is a PEG-based PROTAC linker. m-PEG12-OH can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of ant... | |||
T17978 | Fmoc-PEG12-NHS ester | Others , PROTAC Linker | |
Fmoc-PEG12-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys... | |||
T6555 | K-Ras(G12C) inhibitor 12 | Apoptosis , Raf , Ras | |
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C). | |||
T17407 | Amino-PEG12-amine | H2N-PEG12-CH2CH2NH2,PEODA13 | Others , PROTAC Linker |
Amino-PEG12-amine (H2N-PEG12-CH2CH2NH2) is a PEG-based PROTAC linker that can be used in PROTAC synthesis. | |||
T17667 | Boc-NH-PEG12-CH2CH2COOH | Others , PROTAC Linker | |
Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis. | |||
T17668 | Boc-NH-PEG12-NH2 | NHBoc-PEG12-amine | Others , PROTAC Linker |
Boc-NH-PEG12-NH2 (NHBoc-PEG12-amine) is a PEG-based PROTAC linker that can be used in PROTAC synthesis. | |||
T17719 | Cbz-NH-PEG12-C2-acid | Others , PROTAC Linker | |
Cbz-NH-PEG12-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys... | |||
T11738 | K-Ras G12C-IN-4 | Ras | |
K-Ras G12C-IN-4, is a potent Covalent Inhibitor of KRASG12C.. | |||
T78170 | Kras4B G12D-IN-1 | Ras | |
Kras4B G12D-IN-1 is an anticancer agent that functions as an inhibitor of the Kras4B G12D protein. It effectively reduces the expression of Kras protein in mouse embryonic fibroblasts (MEFs) harboring the Kras4B G12D mut... | |||
T17464 | Azide-PEG12-alcohol | Others , PROTAC Linker | |
Azide-PEG12-alcohol is a PEG-based PROTAC linker that can be used in PROTAC synthesis. | |||
T15839 | M-PEG12-amine | Others | |
m-PEG12-amine is a PEG-based PROTAC linker and a non-cleavable 12 unit PEG ADC linker employed in the synthesis of PROTACs[1] and antibody-drug conjugates (ADCs)[2]. | |||
T18566 | Propargyl-PEG12-bromide | Others , PROTAC Linker | |
Propargyl-PEG12-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | |||
T3725 | K-Ras(G12C) Inhibitor 6 | Raf | |
K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro. | |||
T6556 | K-Ras(G12C) inhibitor 9 | Raf | |
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C). |