Powder: -20°C for 3 years | In solvent: -80°C for 1 year
K-Ras G12C-IN-4 is a potent co-valent Inhibitor of KRAS G12C..
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 148.00 | |
2 mg | In stock | $ 218.00 | |
5 mg | In stock | $ 372.00 | |
10 mg | In stock | $ 556.00 | |
25 mg | In stock | $ 896.00 | |
50 mg | In stock | $ 1,220.00 | |
100 mg | In stock | $ 1,650.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 459.00 |
Description | K-Ras G12C-IN-4 is a potent co-valent Inhibitor of KRAS G12C.. |
Targets&IC50 | p-ERK:0.219 μM |
In vitro | Administration of K-Ras G12C-IN-4 for 4 hours inhibits MAPK signaling (p-ERK) in MIA PaCa-2 cells with IC50 of 0.219 μM[1]. In the CellTiter-Glo assay of MIA PaCa-2 cells, the use of K-Ras G12C-IN-4 for 72 hours inhibited its cell viability with IC50 of 0.067 μM[1]. |
Molecular Weight | 561.07 |
Formula | C31H33ClN4O4 |
CAS No. | 2376328-55-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (89.115 mM), ultrasonic and heat to 60°C
You can also refer to dose conversion for different animals. More
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K-Ras G12C-IN-4 2376328-55-9 GPCR/G Protein MAPK Ras Inhibitor K Ras G12C IN 4 inhibit K-Ras G-12C-IN-4 KRas G12CIN4 inhibitor