Powder: -20°C for 3 years | In solvent: -80°C for 1 year
m-PEG12-OH (Dodecaethylene Glycol Monomethyl Ether) is a PEG-based PROTAC linker. m-PEG12-OH can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 29.00 |
Description | m-PEG12-OH (Dodecaethylene Glycol Monomethyl Ether) is a PEG-based PROTAC linker. m-PEG12-OH can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
In vitro | PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | Dodecaethylene Glycol Monomethyl Ether |
Molecular Weight | 560.67 |
Formula | C25H52O13 |
CAS No. | 2050595-03-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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m-PEG12-OH 2050595-03-2 Others PROTAC PROTAC Linker Antibody-drug conjugates linkers m-PEG-12-OH Inhibitor PEG linker ADC Linkers ADC inhibit non-cleavable PROTAC Linkers m PEG12 OH Dodecaethylene Glycol Monomethyl Ether mPEG12OH inhibitor