doxorubicin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1456	Doxorubicin	Hydroxydaunorubicin,Adriamycin	Topoisomerase , AMPK
	Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.		Topoisomerase , AMPK
T1020	Doxorubicin hydrochloride	Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127	Apoptosis , Mitophagy , HBV , HIV Protease , Topoisomerase , Antibacterial , Antibiotic , AMPK , Autophagy
	Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitum...
T31567	Doxorubicin-MVCP	MC-Val-Cit-PAB-Doxorubicin,MC-Val-Cit-PAB-Dox
	Doxorubicin-MVCP (MC-Val-Cit-PAB-Doxorubicin) is a Doxorubicin derivative with an MC-Val-Cit-PAB linker.
T18418	N-(Iodoacetamido)-Doxorubicin		Others
	N-(Iodoacetamido)-Doxorubicin is an ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].		Others
T70775	Zoptarelin doxorubicin
	Zoptarelin doxorubicin, also known as AEZS-108, is an LHRH agonist. Zoptarelin doxorubicin is a peptide agonist of the gonadotropin releasing hormone-1 receptor (GnRH-1R) that is conjugated to the anthracycline antibio...
T15161	Doxorubicin-SMCC		Others
	Doxorubicin-SMCC is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].		Others
T29673	Doxorubicinone	Adriamycinone,Adriamycin Aglycone,Doxorubicin Aglycone
	Adriamycin Aglycone, also known as Doxorubicinone, is an oncolytic agent. It is a metabolite of Doxorubicin which binds to the DNA minor-groove.
T77832	Azide-PEG4-VC-PAB-Doxorubicin
	Azide-PEG4-VC-PAB-Doxorubicin is an agent-linker conjugate for antibody-drug conjugate (ADC) applications, consisting of the cytotoxic anthracycline antibiotic Doxorubicin attached via the Azide-PEG4-VC-PAB linker [1].
T27200	DOX−NOP1 HCl	doxorubicin-NOP1 conjugate,doxorubicin-NOP1 HCl,DOX−NOP1 Hydrochloride
	DOX−NOP1 is a molecular hybrid covalently joining doxorubicin (DOX) and NOP1. DOX−NOP1 showed similar increased toxicity toward resistant cancer cells and, in addition, lower cardiotoxicity than DOX.
T11090	MC-DOXHZN	Doxorubicin(6-maleimidocaproyl)hydrazone	Others
	Mc-doxhzn is a protein-binding prodrug of DOXUbicin (DNA topoisomerase II inhibitor) with acid sensitivity.		Others
TQ0049	MC-DOXHZN hydrochloride	Doxorubicin(6-maleimidocaproyl)hydrazone hydrochloride	Topoisomerase
	MC-DOXHZN hydrochloride is an albumin-binding prodrug of Doxorubicin. Doxorubicin is a DNA topoisomerase II inhibitor.		Topoisomerase
T4469	Nemorubicin	Methoxymorpholinyldoxorubicin,PNU-152243A,PNU 152243	Others
	Nemorubicin (PNU 152243) is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to ...		Others
T6909	NSC348884		Apoptosis , p53
	NSC348884 is a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis, inhibits cell proliferation at an IC50 of 1.7-4.0 μM in distinct cancer cell lines.		Apoptosis , p53
T6928	Pantoprazole	SKF96022,BY1023	Apoptosis , Proton pump , Autophagy
	Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Proton pump , Autophagy
T0161	Pantoprazole Sodium Hydrate	SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate)	Apoptosis , Potassium Channel , Proton pump , Autophagy
	Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Potassium Channel , Proton pump , Autophagy
T6929	Pantoprazole sodium	Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc	Apoptosis , Others , Proton pump , HIF , Autophagy
	Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters...		Apoptosis , Others , Proton pump , HIF , Autophagy
T11090L1	Aldoxorubicin hydrochloride	Aldoxorubicin hydrochloride (1361644-26-9 Free base）	Topoisomerase
	Aldoxorubicin hydrochloride is an albumin-binding prodrug of Doxorubicin, a DNA topoisomerase II inhibitor. Aldoxorubicin hydrochloride is released from albumin under acidic conditions. Aldoxorubicin hydrochloride exhibi...		Topoisomerase
T40736	Doxorubicinol hydrochloride	13-Dihydroadriamycin hydrochloride
	Doxorubicinol hydrochloride, also known as 13-Dihydroadriamycin hydrochloride, is a secondary alcohol metabolite derived from Doxorubicin.
T25349	Doxorubicinol	RP-27706,Antibiotic 27706RP,13-Dihydrodoxorubicin,Adriamycinol,RP 27706
	Doxorubicinol is the major circulating metabolite of doxorubicin with antineoplastic acitivity.
T11090L	Aldoxorubicin	DOXO-EMCH,INNO-206	Topoisomerase
	Aldoxorubicin has effective antitumor activities in various cancer cell lines and in murine tumor models. Aldoxorubicin is an albumin-binding prodrug of Doxorubicin (DNA topoisomerase II inhibitors).		Topoisomerase