Search Result

Search Results for " defensin "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T40470	Human β-defensin-2	Human β-defensin-2,HβD-2
	Human β-defensin-2 (HβD-2) is a cationic skin-antimicrobial peptide (SAP) characterized by its small size and rich cysteine content. It is produced by various epithelial cells and exhibits potent antimicrobial properties...
T40550	Human β-defensin-1	Human β-defensin-1,HβD-1
	Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by epithelial surfaces, circulatory cells, and cells of the reproductive tract. It exhibits antimicrobial activity against ...
T39683	Human β-defensin-3	Human β-defensin-3,HβD-3
	Human β-defensin-3 (HβD-3) is an antibiotic antimicrobial peptide synthesized by epithelial cells. It exhibits potent antimicrobial properties and mitigates inflammatory cytokine responses. HβD-3 efficiently targets vari...
T41134	Defensin HNP-2 human
	Defensin HNP-2 is a naturally occurring antibiotic and monocyte chemotactic peptide synthesized by human neutrophils.
T41135	Defensin HNP-1 human
	Defensin HNP-1 human is a Human neutrophil peptides (HNPs), involved in endothelial cell dysfunction at the time of early atherosclerotic development.Defensin HNP-1 human can regulate the growth of atherosclerosis.
T35451	β-Defensin-2 (human) (trifluoroacetate salt)
	β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cari...
T35453	β-Defensin-4 (human) (trifluoroacetate salt)
	β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It induces migration of monocytes in vitro when used at...
T38103	Defensin HNP-3 (human) (trifluoroacetate salt)
	Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It induces lysis of mammalian cells when used at a concentration of 25 μg/mL. It also inhibits growth o...
T35426	β-Defensin-1 (human) (trifluoroacetate salt)
	β-Defensin-1 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth ofB. adolescentis,L. acidophilus...
T35452	β-Defensin-3 (human) (trifluoroacetate salt)
	β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of the periodontopathogenic and ...
T76501	Defensin HNP 4
	Defensin HNP 4 (HNP 4), an 11-amino acid segment derived from HNP-41-11, exhibits inhibitory effects against both multidrug-resistant and non-resistant strains [1].
T76503	Defensin NP-3A
	Defensin NP-3A (NP-3A; Corticostatin 1), a human granulocyte peptide, exhibits anti-ACTH activity. It belongs to the defensins, a group of antimicrobial peptides known for their antimicrobial and cytotoxic activities [1]...
T80375	Human α-defensin 5		Parasite
	Human α-defensin 5 is an antiviral peptide that inhibits the infection of non-enveloped viruses such as AdV, HPV, and polyomaviruses, with an IC50 range of 0.6-1.25 μM specifically for HPV16. It functions by binding to t...		Parasite
T80362	Human α-Defensin 6
	Human α-Defensin 6, a 32-residue, cysteine-rich peptide, plays a crucial role in mucosal immunity by inhibiting bacterial invasion. It achieves this through the formation of ordered self-assembly fibrils and nanonets, wh...
T80045	Defensin HNP-3 human		Antibiotic
	Defensin HNP-3 human, a cytotoxic antibiotic peptide referred to as "defensin," exhibits inhibitory effects on Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. This compound is first synthesized as a ...		Antibiotic
T76063	Beta-defensin 1, pig
	Beta-defensin 1, pig, is an antimicrobial peptide predominantly located in the tongue mucosa of pigs. It exhibits activity against a variety of bacteria including Escherichia coli, Salmonella typhimurium, Listeria monocy...
T76063L	Beta-defensin 1, pig TFA
	Beta-defensin 1, pig TFA, an antimicrobial peptide predominantly located in the tongue mucosa of pigs, exhibits activity against a diverse range of bacteria including Escherichia coli, Salmonella typhimurium, Listeria mo...
T80323	Bovine neutrophil beta-defensin 12	BNBD-12
	Bovine neutrophil beta-defensin 12, an antimicrobial peptide originating from bovine neutrophils, exhibits antibacterial properties against Escherichia coli and Staphylococcus aureus [1].
T76070	Defensin HNP-1 human TFA
	Defensin HNP-1 Human TFA, a human neutrophil peptide (HNP), plays a role in the early development of atherosclerosis by contributing to endothelial cell dysfunction. Additionally, it has demonstrated broad-spectrum antim...
T76064	Beta-defensin 103 isoform X1, pig
	Beta-defensin 103 isoform X1, pig, is an antimicrobial peptide prevalent in various organisms, playing a crucial role in the initial defense strategy of their innate immune system against pathogens [1].
T76064L	Beta-defensin 103 isoform X1, pig TFA
	Beta-defensin 103 isoform X1, pig TFA, is an antimicrobial peptide present in various living organisms, playing a crucial role in the initial defense of their innate immune system against pathogens [1].
T14781	Brilacidin	PMX 30063	Others
	Brilacidin is a nonpeptidic anti-infective in a new class of defensin mimetics used for the research of eye infections.		Others
T80340	ROAD-1
	ROAD-1, a Rhesus Macaque oral mucosal α-defensin, exhibits antimicrobial activity against S. aureus, E. coli, and C. albicans [1].
T38608	Brilacidin tetrahydrochloride	PMX 30063 tetrahydrochloride
	Brilacidin tetrahydrochloride (PMX 30063 tetrahydrochloride) is a defensin mimetic antibiotic compound, exhibiting potent anti-infective antimicrobial activity against a range of bacteria. It demonstrates MIC90 values of...
T81295	Retrocyclin-1
	Retrocyclin-1, a Theta-defensin, selectively binds to carbohydrate-rich surface molecules such as fetuin, gp120 (K d =35.4 nM), CD4 (K d =31 nM), and galactosylceramide (K d =24.1 nM) [1], thereby shielding cells from HI...
T80255	CHRG01
	CHRG01, a biologically active peptide, originates from the C-terminal amino acids 54 to 67 of human β-defensin 3 (hBD-3), with a modified structure wherein all cysteine (Cys) residues are replaced by serine (Ser) to elim...

Compounds

Human β-defensin-2

T40470

Synonym: Human β-defensin-2,HβD-2

Target:

Human β-defensin-1

T40550

Synonym: Human β-defensin-1,HβD-1

Target:

Human β-defensin-3

T39683

Synonym: Human β-defensin-3,HβD-3

Target:

Defensin HNP-2 human

T41134

Synonym:

Target:

Defensin HNP-1 human

T41135

Synonym:

Target:

β-Defensin-2 (human) (trifluoroacetate salt)

T35451

Synonym:

Target:

β-Defensin-4 (human) (trifluoroacetate salt)

T35453

Synonym:

Target:

Defensin HNP-3 (human) (trifluoroacetate salt)

T38103

Synonym:

Target:

β-Defensin-1 (human) (trifluoroacetate salt)

T35426

Synonym:

Target:

β-Defensin-3 (human) (trifluoroacetate salt)

Defensin HNP-3 human

T80045

Synonym:

Target: Antibiotic

Beta-defensin 1, pig

T76063

Synonym:

Target:

Beta-defensin 1, pig TFA

T76063L

Synonym:

Target:

Bovine neutrophil beta-defensin 12

T80323

Synonym: BNBD-12

Target:

Defensin HNP-1 human TFA

T76070

Synonym:

Target:

Beta-defensin 103 isoform X1, pig

T76064

Synonym:

Target:

Beta-defensin 103 isoform X1, pig TFA

Brilacidin tetrahydrochloride

T38608

Synonym: PMX 30063 tetrahydrochloride

Cat No.	Product Name	Synonyms	Targets
T80344	Aeschna defensin
	Aeschna defensin is an antimicrobial peptide sourced from the hemolymph of aquatic dragonfly larvae, exhibiting potent activity against Gram-positive bacteria [1].
TQ0216	Ercalcitriol	1α,25-Dihydroxy Vitamin D2	Others
	Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2. Ercalcitriol, as the physiological activated form of vitamin D, can strengthen immunity via regulation of cathelicidin antimicrobial peptid...		Others

Natural Products

Synonym: 1α,25-Dihydroxy Vitamin D2

Target: Others

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-02541	Beta Defensin 1/DEFB1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization i...
TMPH-00460	Defensin-like protein 1 Protein, Dahlia merckii, Recombinant (B2M & His)	Dahlia merckii	E. coli
	Defensin-like protein 1 Protein, Dahlia merckii, Recombinant (B2M & His) is expressed in E. coli.
TMPJ-01243	DEFB4 Protein, Human, Recombinant	Human	E. coli
	Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1,...
TMPH-01005	DEFB128 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Has antibacterial activity. DEFB128 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 16.0 kDa and the accession number is Q7...
TMPH-01006	DEFB129 Protein, Human, Recombinant (His & Myc)	Human	P. pastoris (Yeast)
	Has antibacterial activity. DEFB129 Protein, Human, Recombinant (His & Myc) is expressed in yeast with C-6xHis-Myc tag. The predicted molecular weight is 21.8 kDa and the accession number is Q9H1M3.
TMPJ-00003	DEFB1 Protein, Human, Recombinant	Human	E. coli
	β-Defensin 1 (DEFB1) is a member of the β-defensin family, which is highly expressed by epithelial cells. β-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a si...
TMPH-03148	DEFB126 Protein, Pongo pygmaeus, Recombinant (GST)	Pongo pygmaeus	P. pastoris (Yeast)
	DEFB126 Protein, Pongo pygmaeus, Recombinant (GST) is expressed in yeast with N-GST tag. The predicted molecular weight is 31.9 kDa and the accession number is A4H244.
TMPH-03082	DEFB106A Protein, Pan troglodytes, Recombinant (His & KSI)	Chimpanzee	E. coli
	Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. DEFB106A Protein, Pan troglodytes, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molec...
TMPY-00346	DEFA3 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	DEFA3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.8 kDa and the accession number is P59666.
TMPY-04170	DEFB1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	The DEFB1 gene, encoding for the constitutively expressed human beta-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been rep...
TMPJ-00667	DEFB4A Protein, Human, Recombinant	Human	E. coli
	β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of t...
TMPH-02504	DEFA5 Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	Probably contributes to the antimicrobial barrier function of the small bowel mucosa. DEFA5 Protein, Mouse, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31...
TMPH-03101	DEFB1 Protein, Pig, Recombinant (GST)	Sus scrofa (Pig)	E. coli
	Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization i...
TMPH-02543	DEFB33 Protein, Mouse, Recombinant (His & Myc & SUMO)	Mouse	E. coli
	Has antibacterial activity.
TMPH-02545	DEFB6 Protein, Mouse, Recombinant (His & KSI)	Mouse	E. coli
	Has potent antibacterial activity against E.coli (ATCC 25922). DEFB6 Protein, Mouse, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 19.8 kDa and ...
TMPH-02542	DEFB19 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Has antibacterial activity.
TMPY-02835	DEFB103A Protein, Human, Recombinant (His)	Human	E. coli
	Beta-defensin 3 is a member of the defensin family. Defensin family is comprised by microbicidal and cytotoxic peptides made by neutrophils. Members of the beta-defensin 3 family are highly similar in protein sequence. B...
TMPY-05525	Art v 1 Protein, Artemisia vulgaris, Recombinant (His)	Artemisia vulgaris	HEK293 Cells
	Art v 1 Protein, Artemisia vulgaris, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.2 kDa and the accession number is Q84ZX5.1.
TMPH-02544	DEFB4 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CC...
TMPH-00063	Defensin-1 Protein, Apis mellifera, Recombinant (His)	Apis mellifera	E. coli
	Found in royal jelly and in hemolymph, potent antibacterial protein against Gram-positive bacteria at low concentration. Defensin-1 Protein, Apis mellifera, Recombinant (His) is expressed in E. coli expression system wit...
TMPH-01772	DEFA1 Protein, Human, Recombinant (GST)	Human	E. coli
	Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing thei...
TMPY-00542	DEFB127 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	DEFB127 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 31.8 kDa and the accession number is A0A2J8MRU9.
TMPH-02503	DEFA1 Protein, Mouse, Recombinant (GST & His)	Mouse	E. coli
	Probably contributes to the antimicrobial barrier function of the small bowel mucosa. Has antibacterial activity against attenuated mutants of S.typhimurium. DEFA1 Protein, Mouse, Recombinant (GST & His) is expressed in ...
TMPY-01115	DEFB119 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	DEFB119 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 33.9 kDa and the accession number is Q8N690-1.
TMPH-00061	Defensin-1 Protein, Apis mellifera carnica, Recombinant (His & KSI)	Apis mellifera carnica	E. coli
	Found in royal jelly and in hemolymph, potent antibacterial protein against Gram-positive bacteria at low concentration. Defensin-1 Protein, Apis mellifera carnica, Recombinant (His & KSI) is expressed in E. coli express...
TMPH-03231	AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO)	Raphanus sativus	E. coli
	Possesses antifungal activity sensitive to inorganic cations. Induces potential changes in fungal membranes and increased K(+) efflux and Ca(2+) uptake. AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO) is express...
TMPH-02255	Trypsin-2 Protein, Human, Recombinant (K23Q & S167G, His)	Human	E. coli
	In the ileum, may be involved in defensin processing, including DEFA5.
TMPH-01607	LCE3A Protein, Human, Recombinant (His)	Human	E. coli
	A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and G...