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Search Results for " ca2 "

20

Compounds

Cat No. Product Name Synonyms Targets
T10659 Ca2+ channel agonist 1 Calcium Channel , CDK
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction.
T13047 Synta66 Calcium Channel
Synta66 is a store-operated calcium entry channel Orai inhibitor, and used for the research of neurological disease.
T16873 SERCA2a activator 1 Calcium Channel
SERCA2a activator 1 is a sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a activator. SERCA2a activator 1 decreases phospholamban inhibition and enhances the systolic and diastolic functions of the heart.
TN2322 Yangambin Calcium Channel , PAFR
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti...
T10885 CRAC intermediate 2 Others , Calcium Channel
CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis.
T8674 SR33805 Calcium Channel
SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)
TN1121 Evocarpine Apoptosis , cAMP , Anti-infection , Calcium Channel , Antibacterial
Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.
T12015 Methyl homoveratrate Others
Methyl homoveratrate, a McN5691 (RWJ-26240) metabolite detected in vivo in plasma, urine, and fecal extracts, functions as a voltage-sensitive calcium channel blocker.
T24984 5J-4 Calcium Channel
5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE). 5J-4 reduces the production of IL-17 and decreases the expression of RORα and RORγt.
T7603 Pinaverium bromide Calcium Channel
Pinaverium bromide is an calcium channel blocker with Antispasmodic and effectively relieves pain, diarrhea and intestinal discomfort.
T6S1418 Praeruptorin C Antioxidant , Calcium Channel
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ...
T10884 CRAC intermediate 1 5-(S)-Fluorowillardiine Calcium Channel
CRAC intermediate 1 (5-(S)-Fluorowillardiine) is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors.
T4727 Taurolithocholic acid sodium salt Sodium taurolithocholate Others , Calcium Channel
Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but not to M2 or M3 receptors.
T3651 YM-58483 YM 58483,BTP2 Calcium Channel
YM-58483 (BTP2) is a specific and effective inhibitor of CRAC channels and subsequent Ca2+ signals.
T8787 Drotaverine hydrochloride PDE
Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor,and is an antispasmodic drug, used to enhance cervical dilation during childbirth. Drotaverine hydrochloride is structurally rela...
T5457 SN 6 SN6 Calcium Channel , Na+/Ca2+ Exchanger
SN 6 (SN6) is a selective Na+/Ca2+ exchanger (NCX) inhibitor (IC50s of NCX1: 2.9 μM , NCX2: 16 μM ,NCX3: 8.6 μM)
T15423 GSK-7975A Calcium Channel
GSK-7975A is a potent and orally available inhibitor of CRAC channel.
T8863 VK-II-36 Others
VK-II-36, a carvedilol analog, suppresses sarcoplasmic reticulum (SR) Ca(2+) release but does not block the β-receptor.
T0728 Ethosuximide Zarontin Calcium Channel
Ethosuximide (Zarontin) is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by other types of seizures.
T2003 ISX-9 Isoxazole 9,Isoxazole 9 (ISX-9) Calcium Channel , Wnt/beta-catenin
ISX-9 (Isoxazole 9) is necessary to activate neuron-specific genes as neurogenesis inducer.
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TargetMol