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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10659 | Ca2+ channel agonist 1 | Calcium Channel , CDK | |
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction. | |||
T13047 | Synta66 | Calcium Channel | |
Synta66 is a store-operated calcium entry channel Orai inhibitor, and used for the research of neurological disease. | |||
T16873 | SERCA2a activator 1 | Calcium Channel | |
SERCA2a activator 1 is a sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a activator. SERCA2a activator 1 decreases phospholamban inhibition and enhances the systolic and diastolic functions of the heart. | |||
TN2322 | Yangambin | Calcium Channel , PAFR | |
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti... | |||
T10885 | CRAC intermediate 2 | Others , Calcium Channel | |
CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis. | |||
T8674 | SR33805 | Calcium Channel | |
SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively) | |||
TN1121 | Evocarpine | Apoptosis , cAMP , Anti-infection , Calcium Channel , Antibacterial | |
Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels. | |||
T12015 | Methyl homoveratrate | Others | |
Methyl homoveratrate, a McN5691 (RWJ-26240) metabolite detected in vivo in plasma, urine, and fecal extracts, functions as a voltage-sensitive calcium channel blocker. | |||
T24984 | 5J-4 | Calcium Channel | |
5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE). 5J-4 reduces the production of IL-17 and decreases the expression of RORα and RORγt. | |||
T7603 | Pinaverium bromide | Calcium Channel | |
Pinaverium bromide is an calcium channel blocker with Antispasmodic and effectively relieves pain, diarrhea and intestinal discomfort. | |||
T6S1418 | Praeruptorin C | Antioxidant , Calcium Channel | |
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ... | |||
T10884 | CRAC intermediate 1 | 5-(S)-Fluorowillardiine | Calcium Channel |
CRAC intermediate 1 (5-(S)-Fluorowillardiine) is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors. | |||
T4727 | Taurolithocholic acid sodium salt | Sodium taurolithocholate | Others , Calcium Channel |
Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but not to M2 or M3 receptors. | |||
T3651 | YM-58483 | YM 58483,BTP2 | Calcium Channel |
YM-58483 (BTP2) is a specific and effective inhibitor of CRAC channels and subsequent Ca2+ signals. | |||
T8787 | Drotaverine hydrochloride | PDE | |
Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor,and is an antispasmodic drug, used to enhance cervical dilation during childbirth. Drotaverine hydrochloride is structurally rela... | |||
T5457 | SN 6 | SN6 | Calcium Channel , Na+/Ca2+ Exchanger |
SN 6 (SN6) is a selective Na+/Ca2+ exchanger (NCX) inhibitor (IC50s of NCX1: 2.9 μM , NCX2: 16 μM ,NCX3: 8.6 μM) | |||
T15423 | GSK-7975A | Calcium Channel | |
GSK-7975A is a potent and orally available inhibitor of CRAC channel. | |||
T8863 | VK-II-36 | Others | |
VK-II-36, a carvedilol analog, suppresses sarcoplasmic reticulum (SR) Ca(2+) release but does not block the β-receptor. | |||
T0728 | Ethosuximide | Zarontin | Calcium Channel |
Ethosuximide (Zarontin) is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by other types of seizures. | |||
T2003 | ISX-9 | Isoxazole 9,Isoxazole 9 (ISX-9) | Calcium Channel , Wnt/beta-catenin |
ISX-9 (Isoxazole 9) is necessary to activate neuron-specific genes as neurogenesis inducer. |