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Search Results for " ct1 "

12

Compounds

Cat No. Product Name Synonyms Targets
T62822 CT1-3
CT1-3 is a potent anti-cancer agent. CT1-3 regulates the JNK/Bcl-2/Bax/XIAP pathway, which induces mitochondria-mediated apoptosis. CT1-3 regulates the E-cadherin/Snail axis to inhibit epithelial mesenchymal transition (...
T27093 CT-1 CT 1 p53
CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.
T6435 CCT129202 Aurora Kinase
CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively. It is less potent to FGFR3, GSK3β, PDGFRβ, etc.
T6303 CCT128930 Akt , PKA , S6 Kinase , Autophagy
CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase.
T6303L CCT128930 hydrochloride CCT128930 hydrochloride(885499-61-6 Free base) Apoptosis , Akt , PKA , mTOR , Autophagy
CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28...
T14903 CCT129957 Calcium Channel , Phospholipase
CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells.
T67727 MCT1-IN-3 Monocarboxylate transporter
MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor. The solute carrier (SLC) monocarboxylate transporter 1 (MCT1; SLC16A1) represents a promising target for the treatment of cancer. MCT1-IN-3 (compound 24) sho...
T4133 CCT196969 Raf , Src
CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It also inhibits SRC, LCK, and the p38 MAPKs.
T79904 PROTAC CDK9/CycT1 Degrader-2 CDK
PROTAC CDK9/CycT1 Degrader-2 inhibits CDK9 with an IC50 of 45 nM [1].
T79187 CT1113
CT1113, a potent inhibitor of both USP28 and USP25, effectively reduces MYC levels in vivo and demonstrates anti-tumor efficacy in a mouse pancreatic cancer CDX model [1].
T26221 MCT1-IN-2 SR13800,SR-13800,SR 13800
SR13800 is a monocarboxylate transporter 1 (MCT1) inhibitor with cell-permeable.
T70400 CDK9/CycT1-IN-93
CDK9/CycT1-IN-93 is a highly specific, ATP-competitive inhibitor of CDK9/CycT1 with antiviral activity.
TargetMol