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Search Results for " cns "

20

Compounds

Cat No. Product Name Synonyms Targets
T10852 CNS-5161 hydrochloride CNS 5161A NMDAR
CNS-5161 hydrochloride (CNS 5161A) is a new antagonist of NMDA ion-channel. It interacts with the NMDA receptor/ion channel site to produce a noncompetitive blockade of the actions of glutamate.
T27055 CNS-5161 CNS 5161
CNS-5161 is an NMDA antagonist.
T26645 Aptiganel CNS 1102,CNS-1102,CNS1102 NMDAR
Aptiganel (CNS-1102) is a non-competitive NMDA antagonist, a peptide that may be used to study acute ischemic stroke.
T69411 CNS-5788
CNS-5788 is a potential ischemia-selective N-methyl-D-aspartate (NMDA) receptor ion-channel blocker
T0183L Pramiracetam Sulfate CNS-1879,CI879,CI-879,CI 879,Pramiracetam
Thurfyl salicylate is a reddening agent for the treatment of musculoskeletal, joint, periarticular, and soft tissue pain.
T9786 Lu AF27139 P2X Receptor
Lu AF27139 is an effective and selective antagonist of P2X7 receptor (IC50s of 12 and 2.4 nM for human and rat, Kis of 22, 54, and 13 nM for mouse, human, and rat, respectively). Lu AF27139 can be used in CNS diseases st...
T7626 Budipine Others
Budipine is a low affinity, N-methyl-D-aspartate receptor antagonist,is an antiparkinsonian agent.
T7688 4-Nonylphenylboronic acid FAAH
4-Nonylphenylboronic acid is a inhibitor of FAAH.
T9697 ASK1-IN-1 ASK
ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays.
T7946 AER-271 Aquaporin
AER-271 is an inhibitor of aquaporin-4.
T7388 GSK805 ROR
GSK805 is a potent, orally bioavailable retinoid-related orphan receptor gamma t (RORγt) inverse agonist that interacts with the receptor's putative ligand binding domain without exerting significant effects on DNA bindi...
T2625 MK-0752 Beta Amyloid , Gamma-secretase
MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM).
T11689 ITI-214 ITI214 PDE
ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = ...
T60003 AC1-IN-1 Adenylyl cyclase
AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).
T1787 Levobupivacaine Sodium Channel
Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZ...
T9070 ASP2905 ASP-2905 Potassium Channel
ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene. It can cross the blood-brain barrier and has antipsychotic activities
T5513 RO-3 P2X Receptor
RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor
T2086 ELN-441958 ELN 441958 Bradykinin Receptor
ELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM. ELN-441958(ELN 441958) is highly selective for B1 over B2 receptors.
T2026 CYM5442 S1P Receptor , LPL Receptor
CYM5442 is an S1P agonist, targeting to Sphingosine.
T3119 JNJ-63533054 JNJ 63533054 GPR
JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM.
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TargetMol