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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60005 | CK1-IN-3 | Casein Kinase | |
CK1-IN-3 is casein kinase 1 (CK1) inhibitor and can be used for research on the treatment or prevention of diseases associated with circadiantiazol rhythm, inflammation diseases. | |||
T5393 | CK1-IN-1 | PUN51207 | p38 MAPK , Casein Kinase |
CK1-IN-1 (PUN51207) is a casein kinase 1 (CK1) inhibitor. CK1-IN-1 has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively. | |||
T79145 | CK1-IN-2 | Casein Kinase | |
CK1-IN-2 (compound Nr.4) is a potent inhibitor of CK1, exhibiting IC50 values of 123 nM for CK1a, 19.8 nM for CK1d, 26.8 nM for CK1e, and 74.3 nM for p38a [1]. | |||
T8987 | Epiblastin A | Casein Kinase | |
Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs). | |||
T22884 | JW 67 | Wnt/beta-catenin | |
JW 67 is an inhibitor of canonical Wnt pathway signaling. JW 67 rapidly reduced active β-catenin with a subsequent downregulation of Wnt target genes, including AXIN2, SP5, and NKD1. | |||
T19913 | CKI-7 | CKI 7 2HCl,CKI-7 dihydrochloride,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl | ROCK , SGK , Casein Kinase , CDK , S6 Kinase |
CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1. | |||
T61843 | CK156 | ||
CK156 is a potent inhibitor of death-associated protein kinase (DAPK), demonstrating high selectivity. In the DRAK1 NanoBRET assay, CK156 exhibits IC50 values of 182 nM, 34 μM, and 39 μM for DRAK1, CK2a1, and CK2a2, resp... | |||
TP1971 | Pseudo RACK1 | ||
Activator of protein kinase C; attached to cell permeabilization Antennapedia domain vector peptide. Consists of peptide derived from the C2 domain of PKC β linked by a disulfide bridge to the Antennapedia domain vector ... | |||
T71654 | APcK110 | ||
APcK110 is a novel Kit inhibitor . APcK110 inhibits proliferation of the mastocytosis cell line HMC1.2 and the SCF-responsive cell line OCI/AML3 in a dose-dependent manner . APcK110 is a more potent inhibitor of OCI/AML3... | |||
T27030 | CK176 | HIV-1 inhibitor-34,HIV-1 inhibitor 34,CK 176,CK-176,HIV-1 inhibitor34 | |
CK176 is a capsid targeted inhibitor of HIV-1 replication. CK176 shows an 11-fold improvement over I-XW-053 in blocking HIV-1 replication in primary human peripheral blood mononuclear cells (PBMCs). | |||
T2440 | IC261 | SU-5607 | Apoptosis , Casein Kinase , CDK |
IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM. | |||
T2449 | D4476 | D 4476,Casein Kinase I Inhibitor | Apoptosis , Casein Kinase , ALK , Autophagy |
D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay). | |||
T6745 | 5-Iodotubercidin | 5-ITu,NSC 113939 | Adenosine Receptor |
5-Iodotubercidin (NSC-113939) is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibits nucleoside transporter, CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC. | |||
T4645 | TA-01 | p38 MAPK , Casein Kinase , Autophagy | |
TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively. | |||
T21915 | TBCA | Casein Kinase II Inhibitor III, TBCA | Casein Kinase |
TBCA (Casein Kinase II Inhibitor III, TBCA) is a highly selective CK2 (casein kinase II) inhibitor, IC50 = 110 nM, Ki = 77 nM. TBCA shows selectivity for CK2 over CK1, DYRK1A and a panel of 27 other kinases. | |||
T2695 | TBB | Casein Kinase II Inhibitor I,NSC 231634,4,5,6,7-tetrabromobenzotriazole | GSK-3 , Casein Kinase , CDK |
TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2). | |||
T10829 | CKI-7 free base | CKI-7 | Casein Kinase |
CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1. | |||
T23224 | (R)-DRF053 dihydrochloride | Others | |
cdk/CK1 inhibitor,potent and ATP-competitive | |||
T16141 | MRT00033659 | Others | |
MRT00033659 is an effective broad-spectrum kinase inhibitor of CK1 (IC50=0.9 µM for CK1δ) and CHK1 (IC50=0.23 µM). MRT00033659 is a pyrazolo-pyridine analogue. It also induces p53 pathway activation and E2F-1 destabiliza... | |||
T83684 | Myelin Basic Protein Peptide (mouse, bovine) TFA | Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu,MBP Peptide | |
Myelin basic protein (MBP) peptide, a selective substrate for protein kinase C (PKC) over protein kinase A (PKA), casein kinase 1 (CK1), CK2, phosphorylase kinase, and calcium/calmodulin-dependent protein kinase (CaMKII)... |