cho — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TQ0146	Ac-DEVD-CHO		Apoptosis , Caspase
	Ac-DEVD-CHO is a specific Caspase-3 inhibitor (Ki: 230 pM).Ac-DEVD-CHO has an inhibitory effect in SLNT-induced apoptosis.		Apoptosis , Caspase
TQ0146L	Ac-DEVD-CHO acetate	Caspase-3 Inhibitor I,N-acetyl-asp-glu-val-asp-al,Ac-DEVD-CHO acetate (169332-60-9 free base)	Caspase
	Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.		Caspase
T41069	CHO-C-PEG2-C-CHO	CHO-C-PEG2-C-CHO
	CHO-C-PEG2-C-CHO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system ...
T21617	MG-115	Z-LL-Nva-CHO	Proteasome
	MG-115 (Z-LL-Nva-CHO) is a potent and reversible inhibitor of proteasome , with K i s of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteas...		Proteasome
T78640	Z-LLF-CHO	Z-Leu-Leu-Phe-CHO	Proteasome
	Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) effectively inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex with a Ki value of 460 nM. Additionally, this compound serves as an inhibitor of NF-κB ...		Proteasome
T80531	Ac-AAVALLPAVLLALLAP-DEVD-CHO	DEVD-CHO-CPP 32	Caspase
	Ac-AAVALLPAVLLALLAP-DEVD-CHO (DEVD-CHO-CPP 32) serves as a potent and reversible inhibitor of caspase-3 [1].		Caspase
T39722	CHO-CH2-PEG1-CH2-Boc	CHO-CH2-PEG1-CH2-Boc
	CHO-CH2-PEG1-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys...
T80624	Ac-VAD-CHO	Ac-Val-Ala-Asp-CHO	Caspase
	Ac-Val-Ala-Asp-CHO (Ac-VAD-CHO) serves as a pan-caspase inhibitor and preserves mitochondrial membrane potential (MMP) while preventing the release of cytochrome c in cells subjected to hypoxia [1].		Caspase
T83205	Ac-DNLD-CHO	Ac-Asp-Asn-Leu-Asp-CHO	Caspase
	Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is an inhibitor of Caspase-3/7, exhibiting IC50 values of 9.89 nM and 245 nM, and approximate Ki values of 0.68 nM and 55.7 nM, respectively. This compound is utilized in the study of...		Caspase
T80735	Z-Gly-Pro-Phe-Leu-CHO	Z-GPFL-CHO	Proteasome
	Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde serving as a selective and potent proteasome inhibitor, demonstrating inhibition constants (Ki) of 1.5 µM, 2.3 µM, and 40.5 µM for branched-chain amino acid-p...		Proteasome
T78586L	Ac-IETD-CHO TFA	Ac-IETD-CHO TFA（191338-86-0 Free base )	Apoptosis , Caspase
	Ac-IETD-CHO TFA is a granzyme B and caspase-8 inhibitor that inhibits caspase8 activity by blocking caspase3 precursor cleavage.Ac-IETD-CHO TFA inhibits Fas-mediated apoptosis.		Apoptosis , Caspase
T41236	Z-FY-CHO
	Z-FY-CHO (Z-Phe-Tyr-CHO) is a specific and potent cathepsin L (CTSL) inhibitor [1] [2].
T2154	MG-132	Z-LLL-al,Z-Leu-Leu-Leu-CHO	Apoptosis , Proteasome , Autophagy
	MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor (IC50=100 nM) that is cell-permeable and reversible. MG-132 acts as an autophagy activator and also induces apoptosis.		Apoptosis , Proteasome , Autophagy
T36350	Cho-Arg (trifluoroacetate salt)
	Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assa...
T29233	Z-LLNle-CHO
	Z-LLNle-CHO is a cell permeable inhibitor of gamma-secretase. Z-LLNle-CHO induces apoptosis of human glioblastoma tumor-initiating cells by proteasome inhibition and mitotic arrest response.
T36368	2H-Cho-Arg (trifluoroacetate salt)
	2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. It forms a complex with plasmid DNA (pDNA) and dec...
T6583	MG-101	ALLN,Ac-LLnL-CHO,Calpain inhibitor I,Calpain inhibitor-1,MG101	Cysteine Protease , Proteasome
	MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.		Cysteine Protease , Proteasome
T19883	Ac-YVAD-CHO	L 709049,L-709049,L709049
	L 709049 is a biologically active compound that is a selective inhibitor of interleukin-1β converting enzyme (Caspase-1). Caspase inhibitors interfere with the initiation of apoptosis and have multiple clinical applicati...
T80513	YVAD-CHO
	YVAD-CHO is an inhibitor of interleukin-1β converting enzyme (ICE, caspase 1) that has been shown to partially mitigate motoneuron death in mice with lesioned facial nerves [1].
T80093	IETD-CHO TFA		Caspase
	IETD-CHO TFA (Caspase-8-IN-1) functions as a potent inhibitor of caspase-8 [1].		Caspase