Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Caspase-3 Inhibitor I is a specific inhibitor of Caspase-3.
Description | Caspase-3 Inhibitor I is a specific inhibitor of Caspase-3. |
In vitro | Pretreatment with the caspase-3 inhibitor Ac-DEVD-CHO or antioxidant NAC blocked SLNT-induced apoptosis[1]. The apoptosis of SP2/0 cells was blocked by a pan-caspase inhibitor Z-VAD-FMK and caspase-3 inhibitor Ac-DEVD-CHO[2]. |
In vivo | Compared with model group, in CI group, the concentrations of serum BUN were decreased significantly at all time points after operation and those of Cr were decreased significantly at 6 hours, then restored to those of the sham group at 12 hours and 24 hours; the concentrations of serum TNF-α, IL-6 were decreased and those of IL-10 elevated significantly at all time points[3]. |
Synonyms | Ac-DEVD-CHO acetate (169332-60-9 free base), 乙酰基-天冬氨酰-谷氨酰-缬氨酰-天冬氨醛, N-acetyl-asp-glu-val-asp-al |
Molecular Weight | 562.52 |
Formula | C22H34N4O13 |
CAS No. | TQ0146L |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
H2O: 40 mg/mL (79.61 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Caspase-3 Inhibitor I TQ0146L 蛋白酶体 凋亡 Caspase Ac-DEVD-CHO acetate (169332-60-9 free base) Caspase 3 Inhibitor I Caspase3 Inhibitor I N-acetyl-asp-glu-val-asp-al Inhibitor inhibitor inhibit