c-2-8 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3671	Vitexin-2"-O-rhamnoside	2''-O-Rhamnosylvitexin,Vitexin-2-O-rhaMnoside,Vitexin-2''-O-rhamnoside,Apigenin-8-C-glucoside	Others
	Vitexin-2"-O-rhamnoside (Apigenin-8-C-glucoside) is a compound contributes to the protection against H O -mediated oxidative stress damage.		Others
T77333L	(Iso)-BMT-124110 Formate	(R)-N-(8-((2-amino-2,4-dimethylpentyl)oxy)-5H-chromeno[3,4-c]pyridin-2-yl)acetamide Formate（1679370-98-9 Free base）	AAK1 (AP2 associated kinase 1)
	(Iso)-BMT-124110 Formate has an inhibitory effect on the protein serine/threonine kinase AAK, and is used in the treatment of Parkinson's disease, schizophrenia, neuropathic pain, and Alzheimer's disease.		AAK1 (AP2 associated kinase 1)
TN5698	8-Glucosyl-5,7-dihydroxy-2-isopropylchromone	5,7-Dihydroxy-2-isopropylchromone 8-C-glucoside
	8-Glucosyl-5,7-dihydroxy-2-isopropylchromone is a natural product for research related to life sciences. The catalog number is TN5698 and the CAS number is 188785-44-6.
T38279	C2-8	C2-8
	C2-8 is an inhibitor of polyglutamine (polyQ) aggregation (IC50s = 25 and 0.05 μM for recombinant HDQ51 and in PC12 cells, respectively). It also inhibits polyQ aggregation in organotypic hippocampal slice cultures isola...
TN5525	Orientin 2''-O-rhamnoside	2''-O-Rhamnosylorientin,Luteolin 8-C-neohesperidoside
	Orientin 2''-O-rhamnoside is a natural product for research related to life sciences. The catalog number is TN5525 and the CAS number is 81398-30-3.
TN3265	Yuehgesin C	8-(3-Ethoxy-2-hydroxy-3-methylbutyl)-7-methoxycoumarin	Others
	Yuehgesin C is a natural product for research related to life sciences. The catalog number is TN3265 and the CAS number is 125072-68-6.		Others
TNU0543	8-Aza-2’-beta-C-methylguanosine
	Nucleoside Derivatives - 2’-Modified nucleosides, 8-Modified purine nucleosides
T14511	BAY1082439		Apoptosis , PI3K
	BAY1082439, an orally bioavailable, selective inhibitor of PI3Kα/β/δ, demonstrates high efficacy in inhibiting the growth of Pten-null prostate cancer [1][2]. Additionally, BAY1082439 is effective against mutated forms o...		Apoptosis , PI3K
T126101	Apigenin 6-C-(2-O-feruloyl)glucoside 8-C-glucoside
	Apigenin 6-C-(2-O-feruloyl)glucoside 8-C-glucoside is a useful organic compound for research related to life sciences and the catalog number is T126101.
T123914	8-C-(2-Rhamnosyl-6-deoxyhexopyranosulyl)luteolin
	8-C-(2-Rhamnosyl-6-deoxyhexopyranosulyl)luteolin is a useful organic compound for research related to life sciences. The catalog number is T123914 and the CAS number is 933463-03-7.
TNU0553	8-Chloro-2’-beta-C-methyl inosine
	Nucleoside Derivatives - 2’-Modified nucleosides; 8-Modified purine nucleosides; Halo-nucleosides
T2235	Dactolisib	BEZ235,NVP-BEZ235	ATM/ATR , PI3K , mTOR , Autophagy
	Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).		ATM/ATR , PI3K , mTOR , Autophagy
T17819	Thalidomide-O-amido-C8-NH2	E3 Ligase Ligand-Linker Conjugates 20,Cereblon Ligand-Linker Conjugates 2	Others
	Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2) is a synthesized E3 ligase ligand-linker conjugate comprising a Thalidomide-based cereblon ligand and a linker. This compound is useful in the synthesis of...		Others
TN1487	Chrysin 6-C-arabinoside 8-C-glucoside		Others
	Chrysin 6-C-arabinoside 8-C-glucoside and chrysin-6-C-glucosyl-8-C-arabinoside are α±-glucosidase inhibitors, α±-glucosidase inhibitors are widely used in the treatment of type 2 diabetes.		Others
TN1488	Chrysin 6-C-glucoside 8-C-arabinoside		Others
	Chrysin 6-C-glucoside 8-C-arabinoside and Chrysin-6-C-arabinosyl-8-C-glucoside are α±-glucosidase inhibitors, α±-glucosidase inhibitors are widely used in the treatment of type 2 diabetes.		Others
T14363	AZ-23	AZ 23,AZ23	Trk receptor
	AZ-23 is an inhibitor of ATP-competitive and Trk kinase A/B/C. For TrkA, TrkB, FGFR1, Flt3, Ret, MuSk, Lck, the IC50s values are 2 nM, 8 nM, 24 nM, 52 nM, 55 nM, 84 nM, 99 nM, respectively.		Trk receptor
T2668	JNK-IN-8	JNK Inhibitor XVI	JNK , c-Kit
	JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM). The selectivity is higher 10-fold than MNK2, Fms and no inhibition of Met, c-Kit, PDGFRβ in A375 cell line.		JNK , c-Kit
T16748	Ridinilazole	SMT19969	Antibacterial
	Ridinilazole (SMT19969) is a novel narrow-spectrum nonabsorbable antibiotic. Ridinilazole showed potent inhibition of C. difficile (MIC90=0.125 mg/L) and was markedly more active than either metronidazole (MIC90 = 8 mg/L...		Antibacterial
T6479	Dovitinib lactate hydrate	Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258	VEGFR , FGFR , FLT , PDGFR , c-Kit
	Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) R...		VEGFR , FGFR , FLT , PDGFR , c-Kit
T6289	Dovitinib	TKI258,CHIR-258	VEGFR , FGFR , FLT , PDGFR , c-Kit
	Dovitinib (CHIR-258) (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to E...		VEGFR , FGFR , FLT , PDGFR , c-Kit