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Search Results for " ags "

Targets

11

Compounds

4

Natural Products

6

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T2693 AG1024 Tyrphostin AG 1024,Tyrphostin,AGS 200 Apoptosis , IGF-1R
AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).
T3144 BML-284 Wnt agonist 1 Wnt/beta-catenin
BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.
T1562 Rebamipide Proamipide,OPC12759 Free radical scavengers , COX , Prostaglandin Receptor
Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis ...
T6540 Ibuprofen Lysine Neoprofen COX
Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.
T1394 Ibuprofen Brufen,(±)-Ibuprofe,Motrin,Advil COX
Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resu...
T8820 BML-284 hydrochloride BML-284 HCL,Wnt agonist 1 HCL Wnt/beta-catenin
BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.
T5858 Sertindole Lu 23-174 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Autophagy
Sertindole (Lu 23-174) is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C (Kds = 2.7, 20, 0.14, and 6 nM, respectively)
T14775 Bragsin2 6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one,Bragsin 2 Others
Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of Afr guanine nucleotide exchange factor BRAG2 that inhibits Arf GTPase acti...
T71081 Nagstatin
Nagstatin is an inhibitor of N-acetyl-beta-D-glucosaminidase and is produced by Streptomyces amakusaensis MG846-fF3.
T14774 Bragsin1 Others
Bragsin1 is a potent and selective and noncompetitive ArfGEF BRAG2 inhibitor, inhibits Arf GTPase activation(IC50 : 3 μM),and with anti-cancer activity.
T79072 KRAS G12D modulator-1 Ras
KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging from 1-10 μM against NEA-G12D, PPI-G12D, and p ERK-AGS, and is utilized in cancer research [1].
Cat No. Product Name Synonyms Targets
TN4629 Nemoralisin C Others
Nemoralisin C shows antiproliferative activity against HepG2, AGS, MCF-7, and A-549 cancer cell lines.
TN4630 Nemoralisin Others
Nemoralisin exhibits weak cytotoxicities (IC50>10 uM) against HepG2, AGS, MCF-7, and A-549 cancer cell lines.
TN4866 Pyracrenic acid Others
Pyracrenic acid is a potent elastase inhibitor with an IC50 value of 1.5 mg/mL. Pyracrenic acid shows DPPH radical scavenging activity. It also shows significant cytotoxic activities against human cancer cells COLO 205 a...
T3930 Taraxerol acetate Taraxeryl acetate Phosphatase , HSV
Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol. A. roxburghiana has antidiabetic activ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01475 Jagged 1 Protein, Human, Recombinant (His) Human HEK293 Cells
Jagged 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 112 kDa and the accession number is P78504-1.
TMPY-02857 GLA/alpha-Galactosidase A Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
GLA/alpha-Galactosidase A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.6 kDa and the accession number is Q8BGZ6.
TMPY-01470 Jagged 1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Jagged 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 137 kDa and the accession number is P78504-1.
TMPY-04930 Notch 2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
NOTCH2 (Notch Receptor 2) is a Protein Coding gene. This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics and play a role in a variety of dev...
TMPK-00466 Notch 2 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Human Notch-2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of ...
TMPK-00465 Notch 2 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Human Notch 2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of ...
TargetMol